Diverse functions of matrix metalloproteinases during fibrosis
Tóm tắt
Từ khóa
Tài liệu tham khảo
Abraham, 2012, Macrophage infiltration and renal damage are independent of matrix metalloproteinase 12 in the obstructed kidney, Nephrology (Carlton), 17, 322, 10.1111/j.1440-1797.2012.01567.x
Aimes, 1995, Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments, J. Biol. Chem., 270, 5872, 10.1074/jbc.270.11.5872
Balbín, 2001, Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation, J. Biol. Chem., 276, 10253, 10.1074/jbc.M007674200
Balbín, 2003, Loss of collagenase-2 confers increased skin tumor susceptibility to male mice, Nat. Genet., 35, 252, 10.1038/ng1249
Benyon, 1999, Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation, Hepatology, 30, 977, 10.1002/hep.510300431
Betsuyaku, 2000, Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin, Am. J. Pathol., 157, 525, 10.1016/S0002-9440(10)64563-4
Cabrera, 2007, Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin, Int. J. Biochem. Cell Biol., 39, 2324, 10.1016/j.biocel.2007.06.022
Carew, 2012, The role of EMT in renal fibrosis, Cell Tissue Res., 347, 103, 10.1007/s00441-011-1227-1
Chen, 2009, Role of matrix metalloproteinases in epithelial migration, J. Cell. Biochem., 108, 1233, 10.1002/jcb.22363
Chen, 2008, Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity, Am. J. Pathol., 172, 1256, 10.2353/ajpath.2008.070891
Chen, 2009, MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation, PLoS ONE, 4, e6565, 10.1371/journal.pone.0006565
Chevalier, 2006, Obstructive nephropathy: towards biomarker discovery and gene therapy, Nat. Clin. Pract. Nephrol., 2, 157, 10.1038/ncpneph0098
Chiaramonte, 2001, Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis, Hepatology, 34, 273, 10.1053/jhep.2001.26376
Chow, 2004, Macrophages in streptozotocin-induced diabetic nephropathy: potential role in renal fibrosis, Nephrol. Dial. Transplant., 19, 2987, 10.1093/ndt/gfh441
Chu, 2011, Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis, Hepatology, 53, 1685, 10.1002/hep.24206
Corry, 2004, Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines, FASEB J., 18, 995, 10.1096/fj.03-1412fje
Craig, 2013, Profibrotic activities for matrix metalloproteinase-8 during bleomycin-mediated lung injury, J. Immunol., 190, 4283, 10.4049/jimmunol.1201043
Datta, 2011, Novel therapeutic approaches for pulmonary fibrosis, Br. J. Pharmacol., 163, 141, 10.1111/j.1476-5381.2011.01247.x
Degryse, 2010, Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis, Am. J. Physiol., 299, L442
Duffield, 2005, Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells, J. Clin. Invest., 115, 1743, 10.1172/JCI22593
Duffield, 2013, Host responses in tissue repair and fibrosis, Annu. Rev. Pathol., 8, 241, 10.1146/annurev-pathol-020712-163930
Dunsmore, 1998, Matrilysin expression and function in airway epithelium, J. Clin. Invest., 102, 1321, 10.1172/JCI1516
Eddy, 2000, Interstitial fibrosis in mice with overload proteinuria: deficiency of TIMP-1 is not protective, Kidney Int., 58, 618, 10.1046/j.1523-1755.2000.00208.x
Egeblad, 2002, New functions for the matrix metalloproteinases in cancer progression, Nat. Rev. Cancer, 2, 161, 10.1038/nrc745
Endo, 2011, Matrix metalloproteinase-13 promotes recovery from experimental liver cirrhosis in rats, Pathobiology, 78, 239, 10.1159/000328841
England, 2011, Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12, Am. J. Physiol., 301, L519
Fallowfield, 2007, Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis, J. Immunol., 178, 5288, 10.4049/jimmunol.178.8.5288
Flechsig, 2010, Loss of matrix metalloproteinase-13 attenuates murine radiation-induced pulmonary fibrosis, Int. J. Radiat. Oncol. Biol. Phys., 77, 582, 10.1016/j.ijrobp.2009.12.043
Foronjy, 2008, Transgenic expression of matrix metalloproteinase-1 inhibits myocardial fibrosis and prevents the transition to heart failure in a pressure overload mouse model, Hypertens. Res., 31, 725, 10.1291/hypres.31.725
Garbacki, 2009, Matrix metalloproteinase 12 silencing: a therapeutic approach to treat pathological lung tissue remodeling?, Pulm. Pharmacol. Ther., 22, 267, 10.1016/j.pupt.2009.03.001
García-Prieto, 2010, Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10, PLoS ONE, 5, e13242, 10.1371/journal.pone.0013242
Gill, 2008, Metalloproteinases and their inhibitors: regulators of wound healing, Int. J. Biochem. Cell Biol., 40, 1334, 10.1016/j.biocel.2007.10.024
Gill, 2010, Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury, Am. J. Pathol., 176, 64, 10.2353/ajpath.2010.090158
Gill, 2010, Mouse models of MMP and TIMP function, Methods Mol. Biol., 622, 31, 10.1007/978-1-60327-299-5_2
Gough, 2006, Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice, J. Clin. Invest., 116, 59, 10.1172/JCI25074
Greenlee, 2006, Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation, J. Immunol., 177, 7312, 10.4049/jimmunol.177.10.7312
Hadler-Olsen, 2011, Regulation of matrix metalloproteinase activity in health and disease, FEBS J., 278, 28, 10.1111/j.1742-4658.2010.07920.x
Hernandez-Barrantes, 2000, Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation, J. Biol. Chem., 275, 12080, 10.1074/jbc.275.16.12080
Hu, 2007, Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats, J. Gene Med., 9, 217, 10.1002/jgm.1009
Hu, 2010, Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null mice, Circulation, 121, 1637, 10.1161/CIRCULATIONAHA.109.914945
Huang, 2009, Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways, FASEB J., 23, 4317, 10.1096/fj.08-128801
Hung, 2013, Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis, Am. J. Respir. Crit. Care Med., 188, 820, 10.1164/rccm.201212-2297OC
Iimuro, 2008, Matrix metalloproteinase gene delivery for liver fibrosis, Pharm. Res., 25, 249, 10.1007/s11095-007-9311-7
Iimuro, 2003, Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat, Gastroenterology, 124, 445, 10.1053/gast.2003.50063
Iwano, 2002, Evidence that fibroblasts derive from epithelium during tissue fibrosis, J. Clin. Invest., 110, 341, 10.1172/JCI0215518
Jirouskova, 2012, Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis, PLoS ONE, 7, e46271, 10.1371/journal.pone.0046271
Kaar, 2008, Matrix metalloproteinase-1 treatment of muscle fibrosis, Acta Biomater, 4, 1411, 10.1016/j.actbio.2008.03.010
Kang, 2007, Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12, J. Biol. Chem., 282, 7723, 10.1074/jbc.M610764200
Kassiri, 2009, Loss of TIMP3 enhances interstitial nephritis and fibrosis, J. Am. Soc. Nephrol., 20, 1223, 10.1681/ASN.2008050492
Kaviratne, 2004, IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent, J. Immunol., 173, 4020, 10.4049/jimmunol.173.6.4020
Kawamoto, 2006, Tissue inhibitor of metalloproteinase-3 plays important roles in the kidney following unilateral ureteral obstruction, Hypertens. Res., 29, 285, 10.1291/hypres.29.285
Kim, 2001, TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy, J. Am. Soc. Nephrol., 12, 736, 10.1681/ASN.V124736
Kim, 2005, Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice, Am. J. Respir. Cell Mol. Biol., 33, 271, 10.1165/rcmb.2005-0111OC
Kim, 2006, Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix, Proc. Natl. Acad. Sci. USA, 103, 13180, 10.1073/pnas.0605669103
Kim, 2011, Antifibrotic effect of MMP13-encoding plasmid DNA delivered using polyethylenimine shielded with hyaluronic acid, Mol. Ther., 19, 355, 10.1038/mt.2010.262
Kisseleva, 2007, Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis, J. Gastroenterol. Hepatol., 22, S73, 10.1111/j.1440-1746.2006.04658.x
Kolodsick, 2003, Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation, Am. J. Respir. Cell Mol. Biol., 29, 537, 10.1165/rcmb.2002-0243OC
Kriz, 2011, Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?, J. Clin. Invest., 121, 468, 10.1172/JCI44595
Lanone, 2002, Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling, J. Clin. Invest., 110, 463, 10.1172/JCI0214136
LeBleu, 2013, Origin and function of myofibroblasts in kidney fibrosis, Nat. Med., 19, 1047, 10.1038/nm.3218
Lee, 2001, Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1), J. Exp. Med., 194, 809, 10.1084/jem.194.6.809
Leeming, 2011, A novel marker for assessment of liver matrix remodeling: an enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M), Biomarkers, 16, 616, 10.3109/1354750X.2011.620628
Li, 2002, Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury, Cell, 111, 635, 10.1016/S0092-8674(02)01079-6
Lin, 2008, Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney, Am. J. Pathol., 173, 1617, 10.2353/ajpath.2008.080433
Liu, 2010, New insights into epithelial-mesenchymal transition in kidney fibrosis, J. Am. Soc. Nephrol., 21, 212, 10.1681/ASN.2008121226
Liu, 2011, Cellular and molecular mechanisms of renal fibrosis, Nat. Rev. Nephrol., 7, 684, 10.1038/nrneph.2011.149
Lozano, 2012, Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010, Lancet, 380, 2095, 10.1016/S0140-6736(12)61728-0
Madala, 2010, Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis, J. Immunol., 184, 3955, 10.4049/jimmunol.0903008
Manicone, 2008, Matrix metalloproteinases as modulators of inflammation, Semin. Cell Dev. Biol., 19, 34, 10.1016/j.semcdb.2007.07.003
Manicone, 2009, Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin), Am. J. Pathol., 175, 2319, 10.2353/ajpath.2009.090101
Manoury, 2006, Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice, J. Inflamm. (Lond), 3, 2, 10.1186/1476-9255-3-2
Matute-Bello, 2007, Essential role of MMP-12 in Fas-induced lung fibrosis, Am. J. Respir. Cell Mol. Biol., 37, 210, 10.1165/rcmb.2006-0471OC
McCawley, 2001, Matrix metalloproteinases: they’re not just for matrix anymore!, Curr. Opin. Cell Biol., 13, 534, 10.1016/S0955-0674(00)00248-9
McGuire, 2003, Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium, Am. J. Pathol., 162, 1831, 10.1016/S0002-9440(10)64318-0
McQuibban, 2000, Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3, Science, 289, 1202, 10.1126/science.289.5482.1202
McQuibban, 2001, Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1, J. Biol. Chem., 276, 43503, 10.1074/jbc.M107736200
McQuibban, 2002, Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo, Blood, 100, 1160, 10.1182/blood.V100.4.1160.h81602001160_1160_1167
Menghini, 2009, Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice, Gastroenterology, 136, 663, 10.1053/j.gastro.2008.10.079
Mouratis, 2011, Modeling pulmonary fibrosis with bleomycin, Curr. Opin. Pulm. Med., 17, 355, 10.1097/MCP.0b013e328349ac2b
Murphy, 2011, Localizing matrix metalloproteinase activities in the pericellular environment, FEBS J., 278, 2, 10.1111/j.1742-4658.2010.07918.x
Murthy, 2010, Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1, J. Biol. Chem., 285, 25062, 10.1074/jbc.M109.099655
Onozuka, 2011, Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice, Biochem. Biophys. Res. Commun., 406, 134, 10.1016/j.bbrc.2011.02.012
Parks, 2004, Matrix metalloproteinases as modulators of inflammation and innate immunity, Nat. Rev. Immunol., 4, 617, 10.1038/nri1418
Ra, 2007, Control of matrix metalloproteinase catalytic activity, Matrix Biol., 26, 587, 10.1016/j.matbio.2007.07.001
Radbill, 2011, Loss of matrix metalloproteinase-2 amplifies murine toxin-induced liver fibrosis by upregulating collagen I expression, Dig. Dis. Sci., 56, 406, 10.1007/s10620-010-1296-0
Raghu, 2006, Incidence and prevalence of idiopathic pulmonary fibrosis, Am. J. Respir. Crit. Care Med., 174, 810, 10.1164/rccm.200602-163OC
Rock, 2011, Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition, Proc. Natl. Acad. Sci. USA, 108, E1475, 10.1073/pnas.1117988108
Rosas, 2008, MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis, PLoS Med., 5, e93, 10.1371/journal.pmed.0050093
Rowe, 2011, Hepatocyte-derived Snail1 propagates liver fibrosis progression, Mol. Cell. Biol., 31, 2392, 10.1128/MCB.01218-10
Sela-Passwell, 2010, Structural and functional bases for allosteric control of MMP activities: can it pave the path for selective inhibition?, Biochim. Biophys. Acta, 1803, 29, 10.1016/j.bbamcr.2009.04.010
Seltzre, 1999, Native type I collagen is not a substrate for MMP2 (gelatinase A), J. Invest. Dermatol., 112, 993, 10.1046/j.1523-1747.1999.00616.x
Sen, 2010, Deficiency of matrix metalloproteinase-13 increases inflammation after acute lung injury, Exp. Lung Res., 36, 615, 10.3109/01902148.2010.497201
Siller-López, 2004, Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis, Gastroenterology, 126, 1122, 10.1053/j.gastro.2003.12.045
Sun, 2011, New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis, Am. J. Physiol., 300, L341
Takamiya, 2013, Experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice, Nephrol. Dial. Transplant., 28, 55, 10.1093/ndt/gfs387
Tam, 2004, Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities, J. Biol. Chem., 279, 43336, 10.1074/jbc.M407186200
Tocchi, 2013, Functional interactions between matrix metalloproteinases and glycosaminoglycans, FEBS J., 280, 2332, 10.1111/febs.12198
Uchinami, 2006, Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis, Hepatology, 44, 420, 10.1002/hep.21268
Vaillant, 2001, Regulation of hepatic fibrosis and extracellular matrix genes by the th response: new insight into the role of tissue inhibitors of matrix metalloproteinases, J. Immunol., 167, 7017, 10.4049/jimmunol.167.12.7017
Van den Steen, 2000, Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact, Blood, 96, 2673, 10.1182/blood.V96.8.2673
Van den Steen, 2003, Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities, Eur. J. Biochem., 270, 3739, 10.1046/j.1432-1033.2003.03760.x
Van Lint, 2007, Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation, J. Leukoc. Biol., 82, 1375, 10.1189/jlb.0607338
Veidal, 2011, MMP mediated degradation of type VI collagen is highly associated with liver fibrosis—identification and validation of a novel biochemical marker assay, PLoS ONE, 6, e24753, 10.1371/journal.pone.0024753
Wang, 2010, Mice lacking the matrix metalloproteinase-9 gene reduce renal interstitial fibrosis in obstructive nephropathy, Am. J. Physiol., 299, F973
Wang, 2011, Tissue inhibitor of metalloproteinase 1 (TIMP-1) deficiency exacerbates carbon tetrachloride-induced liver injury and fibrosis in mice: involvement of hepatocyte STAT3 in TIMP-1 production, Cell Biosci, 1, 14, 10.1186/2045-3701-1-14
White, 2005, Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity, Am. J. Respir. Cell Mol. Biol., 32, 135, 10.1165/rcmb.2004-0126OC
Wynn, 2004, Fibrotic disease and the T(H)1/T(H)2 paradigm, Nat. Rev. Immunol., 4, 583, 10.1038/nri1412
Wynn, 2011, Integrating mechanisms of pulmonary fibrosis, J. Exp. Med., 208, 1339, 10.1084/jem.20110551
Wynn, 2012, Mechanisms of fibrosis: therapeutic translation for fibrotic disease, Nat. Med., 18, 1028, 10.1038/nm.2807
Yamashita, 2011, Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis, Am. J. Pathol., 179, 1733, 10.1016/j.ajpath.2011.06.041
Yoshiji, 2000, Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model, Hepatology, 32, 1248, 10.1053/jhep.2000.20521
Yoshiji, 2002, Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse, Hepatology, 36, 850
Yu, 2000, Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis, Genes Dev., 14, 163, 10.1101/gad.14.2.163
Yu, 2012, Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans, Am. J. Respir. Crit. Care Med., 186, 752, 10.1164/rccm.201202-0302OC