Diverse Roles of the Nuclear Orphan Receptor CAR in Regulating Hepatic Genes in Response to Phenobarbital
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Aynaci, 2001, Effect of antiepileptic drugs on plasm lipoproteins (s) and other lipid levels in childhood., J Child Neurol, 16, 367, 10.1177/088307380101600511
Buehel, 2001, MAPS: a microarray project system for gene expression experiment information and data validation., Bioinformatic, 17, 564, 10.1093/bioinformatics/17.6.564
Chen, 1997, Ratio-based decisions and the quantitative analysis of cDNA microarray microarray images., J Biomed Optics, 2, 364, 10.1117/12.281504
DeRisi, 1997, Exploring the metabolic and genetic control of gene expression on a genomic scale., Science (Wash DC), 278, 680, 10.1126/science.278.5338.680
Eiris, 1995, Effects of long-term treatment with antiepileptic drugs on serum lipid levels in children with epilepsy., Neurology, 45, 1155, 10.1212/WNL.45.6.1155
Eisen, 1998, Cluster analysis and display of genome-wide expression patterns., Proc Natl Acad Sci USA, 95, 14863, 10.1073/pnas.95.25.14863
Frueh, 1997, Extent and character of phenobarbital-mediated changes in gene expression in the liver., Mol Pharmacol, 51, 363, 10.1016/S0026-895X(24)13475-X
Garcia-Allan, 2000, Identification of phenobarbitone-modulated genes in mouse liver by differential display., J Biochem Mol Toxicol, 14, 65, 10.1002/(SICI)1099-0461(2000)14:2<65::AID-JBT1>3.0.CO;2-#
Heng, 1997, A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans., Biochem J, 325, 741, 10.1042/bj3250741
Honkakoski, 1998, Activation by diverse xenochemicals of the 51-base pair phenobarbital- responsive enhancer module in the CYP2B10 gene., Mol Pharmacol, 53, 597, 10.1124/mol.53.4.597
Honkakoski, 1998, Regulatory DNA elements of phenobarbital-response cytochrome CYP2B genes., J Biochem Mol Toxicol, 12, 3, 10.1002/(SICI)1099-0461(1998)12:1<3::AID-JBT2>3.0.CO;2-P
Honkakoski, 1998, The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene., Mol Cell Biol, 18, 5652, 10.1128/MCB.18.10.5652
Kawamoto, 1999, Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene., Mol Cell Biol, 19, 6318, 10.1128/MCB.19.9.6318
Koneru, 1995, Studies of hepatic warm ischemia in the obese Zucker rat., Transplantation, 59, 942, 10.1097/00007890-199504150-00003
Leclercq, 2000, CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis., J Clin Invest, 105, 1067, 10.1172/JCI8814
Park, 1996, Phenobarbital induction mediated by a distal CYP2B2 sequence in rat liver transiently transfected in situ., J Biol Chem, 271, 23725, 10.1074/jbc.271.39.23725
Ramsden, 1999, Phenobarbital responsiveness conferred by the 5′-flanking region of the rat CYP2B2 gene in transgenic mice., Gene, 228, 169, 10.1016/S0378-1119(98)00612-X
Smirlis, 2001, Orphan receptor promiscuity in the induction of cytochrome P450 by xenobiotics., J Biol Chem, 276, 12822, 10.1074/jbc.M005930200
Sueyoshi, 1999, The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene., J Biol Chem, 274, 6043, 10.1074/jbc.274.10.6043
Sueyoshi, 2001, Phenobarbital response elements of cytochrome p450 genes and nuclear receptors., Annu Rev Pharmacol Toxicol, 41, 123, 10.1146/annurev.pharmtox.41.1.123
Sugatani, 2001, The phenobarbital response enhancer module in the human bilirubin UDP- glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR., Hepatology, 33, 1232, 10.1053/jhep.2001.24172
Trottier, 1995, Localization of a phenobarbital-responsive element (PBRE) in the 5′-flanking region of the rat CYP2B2 gene., Gene, 158, 263, 10.1016/0378-1119(94)00916-G
Waxman, 1992, Phenobarbital induction of cytochrome P-450 gene expression., Biochem J, 281, 577, 10.1042/bj2810577
Webb HK, Schneider M, Escaron P, Tchaparian E, Weins T, Schwendner SW, Lehmann J, Shiao A (2001) The role of the nuclear receptor CAR in the expression and regulation of murine drug-metabolizing enzymes. in preparation 2001
Wei, 2000, The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism., Nature (Lond), 407, 920, 10.1038/35038112
Zelko, 2000, Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes., Biochem Biophys Res Commun, 277, 1, 10.1006/bbrc.2000.3557