Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment

Protein Engineering, Design and Selection - Tập 10 Số 4 - Trang 435-444 - 1997
Lars Nieba1, Annemarie Honegger, Claus Krebber, Andreas Plückthun
1Biochemisches Institut, Universität Zürich, Switzerland

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