Diphosphonates: History and mechanisms of action
Tài liệu tham khảo
Anbar, 1973, Fate and toxicity of orally administered polyethylene polyphosphonates, Fed. Cosmet Toxicol, 11, 1001, 10.1016/0015-6264(73)90227-7
Baxter, 1974, Inhibition of vitamin D metabolism by ethane-1-hydroxy-1,1-diphosphonate, Arch. Biochem. Biophys., 164, 655, 10.1016/0003-9861(74)90077-0
Baxter, 1979, Effect of ethane-1-hydroxy-1,1-diphosphonate and vitamin D on bone mineralization, Calcif. Tissue Int., 28, 73, 10.1007/BF02441220
Bijvoet, 1980, APD in Paget's disease of bone: role of the mononuclear phagocyte system?, Arthritis Rheum., 23, 1193, 10.1002/art.1780231018
Bisaz, 1978, Uptake by bone of pyrophosphate, diphosphates and their technetium derivatives, Clin. Sci. Mol. Med., 54, 265
Bisaz, 1976, Disaggregation of hydroxyapatite crystals, Biochim. Biophys. Acta., 451, 560, 10.1016/0304-4165(76)90151-3
Bisaz, 1975, The comparative effects of vitamin D deficiency and ethane-1-hydroxy-1,1-diphosphonate administration on the histology and glycolysis of chick epiphyseal and articular cartilage, Calcif. Tissue Res., 19, 139, 10.1007/BF02563998
Black, 1977, A histomorphometric and biochemical evaluation of the effects of a diphosphonate in corticosteroid-treated rabbits. Bone Histomorphometry, 157
Bonjour, 1973, Influence of a diphosphonate on serum calcium homeostasis, 143, 404
Bonjour, 1973, Intestinal calcium absorption, Ca-binding protein, and Ca-ATPase in diphosphonate-treated rats, Am. J. Physiol., 224, 1011, 10.1152/ajplegacy.1973.224.5.1011
Bonjour, 1973, Reversal of the EHDP inhibition of calcium absorption by 1,25-dihydroxycholecalciferol, Eur. J. Clin. Invest., 3, 44, 10.1111/j.1365-2362.1973.tb00328.x
Bonjour, 1975, Action of 1,25-dihydroxyvitamin D3 and a diphosphonate on calcium metabolism in rats, Am. J. Physiol., 229, 402, 10.1152/ajplegacy.1975.229.2.402
Bonjour, 1978, Parathyroid hormone and renal handling of Pi: effect of dietary Pi and diphosphonates, Am. J. Physiol., 234, F487
Boris, 1979, Inhibition of diphosphonate-blocked bone mineralization. Evidence that calcitonin promotes mineralization, Acta Endocrinol., 91, 351, 10.1530/acta.0.0910351
Boris, 1978, Evidence for the promotion of bone mineralization by 1,25-dihydroxycholecalciferol in the rat unrelated to the correction of deficiencies in serum calcium and phosphorus, J. Nutr., 108, 1899, 10.1093/jn/108.12.1899
Boskey, 1979, Effect of diphosphonates on hydroxyapatite formation induced by calcium-phospholipid-phosphate complexes, Calcif. Tissue Int., 27, 83, 10.1007/BF02441165
Briner, 1971, The control of dental calculus in experimental animals, Int. Dent. J., 21, 61
Bührer, 1940, The inhibiting action of minute amounts of sodium hexametaphosphate on the precipitation of calcium carbonate from ammoniacal solutions, J. Phys. Chem., 44, 552, 10.1021/j150401a002
Cabanela, 1971, The effects of phosphonates on experimental osteoporosis, Calcif. Tissue Int., 8, 114, 10.1007/BF02010128
Caniggia, 1977, Effect of ethane hydroxy diphosphonate (etidronate) on plasma cholesterol and total lipids in man, Artery, 3, 188
Caniggia, 1979, Effect of diphosphonate (sodium etidronate) on kinetics of 131I-cholesterol in man, Artery, 6, 157
Casey, 1972, The effect of polyphloretin phosphate, polyoestradiol phosphate, a diphosphonate and a polyphosphate on calcification induced by dihydrotachysterol in skin, aorta and kidney of rats, Experientia, 28, 137, 10.1007/BF01935714
Chambers, 1980, The cellular basis of bone resorption, Clin. Orthop., 151, 282
Doty, 1972, Diphosphonate influence on bone cell structure and lysosomal activity, J. Bone Joint Surg., 54, 1128
Eisman, 1974, Influence of pyrophosphate and diphosphonates on rat liver adenylate cyclase, Clin. Exp. Pharmacol. Physiol., 1, 13, 10.1111/j.1440-1681.1974.tb00522.x
Ende, 1979, Effects of some diphosphonates on the metabolism of bone in vivo and vitro, Thesis
Eriksson, 1980, Pyrophosphate analogues as inhibition of herpes simplex virus type 1 DNA polymerase, Biochim. Biophys. Acta, 607, 53, 10.1016/0005-2787(80)90220-8
Evans, 1979, The effects of two diphosphonates on bone metabolism in the rat, Metab. Bone Dis. and Rel. Res., 2, 39, 10.1016/0221-8747(79)90017-1
Evans, 1980, Effects of pyrophosphate and diphosphonates on the dissolution of hydroxyapatites using a flow system, Calcif. Tissue Int., 31, 153, 10.1007/BF02407176
Fast, 1978, The effects of diphosphonates on the growth and glycolysis of connective-tissue cells in culture, Biochem. J., 172, 97, 10.1042/bj1720097
Felix, 1976, The effect of several diphosphonates on acid phosphohydrolases and other lysosomal enzymes, Biochim. Biophys. Acta., 429, 429, 10.1016/0005-2744(76)90291-6
Felix, 1977, Aggregation of calcium oxalate crystals: effect of urin and various inhibitors, Urol. Res., 5, 21, 10.1007/BF00257112
Felix, 1979, Increase in alkaline phosphatase activity in calvaria cells cultured with diphosphonates, Biochem. J., 183, 73, 10.1042/bj1830073
Felix, 1980, Effect of diphosphonate on glycogen content of rabbit ear cartilage cells in culture, Calcif. Tissue Int., 30, 163, 10.1007/BF02408621
Felix, 1981, Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates, Biochem. J., 196, 237, 10.1042/bj1960237
Felix R., Bettex J.D. and Fleisch H. :Effect of diphosphonates on the synthesis of Prostaglandins in cultured calvaria cells. Calc. Tiss. Int., in press.
Fleisch, 1961, Mechanisms of calcification role of collagen, polyphosphates, and phosphatase, Am. J. Physiol., 200, 1296, 10.1152/ajplegacy.1961.200.6.1296
Fleisch, 1962, Isolation from urine of pyrophosphate, a calcification inhibitor, Am. J. Physiol., 203, 671, 10.1152/ajplegacy.1962.203.4.671
Fleisch, 1962, Mechanism of calcification : inhibitory role of pyrophosphate, Nature, 195, 911, 10.1038/195911a0
Fleisch, 1963, Die Pyrophosphatausscheidung im Harn beim gesunden Menschen, Helv. Physiol. Pharmacol. Acta, 21, 88
Fleisch, 1964, Role of nucleation and inhibition in calcification, Clin. Orthop., 32, 170
Fleisch, 1964, The inhibitory effect of pyrophosphate on calcium oxalate precipitation and its relation to urolithiasis, Experientia, 20, 276, 10.1007/BF02151805
Fleisch, 1964, Effect of orthophosphate on urinary pyrophosphate excretion and the prevention of urolithiasis, Lancet, i, 1065, 10.1016/S0140-6736(64)91267-X
Fleisch, 1965, Inhibition of aortic calcification by means of pyrophosphate and polyphosphates, Nature, 207, 1300, 10.1038/2071300b0
Fleisch, 1966, Effect of pyrophosphate on dissolution of hydroxyapatite and its possible importance in calcium homeostasis, 122, 317
Fleisch, 1966, Effect of condensed phosphates on calcification of chick embryo femurs in tissue culture, Am. J. Physiol., 211, 821, 10.1152/ajplegacy.1966.211.3.821
Fleisch, 1966, Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis, Nature, 212, 901, 10.1038/212901a0
Fleisch, 1968, Influence of pyrophosphate on the transformation of amorphous to crystalline calcium phosphate, Calcif. Tissue Res., 2, 49, 10.1007/BF02279193
Fleisch, 1968, The influence of pyrophosphate analogues (diphosphonates) on the precipitation and dissolution of calcium phosphate in vitro and in vivo, Calcif. Tissue Res., 2
Fleisch, 1969, Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo, Science, 165, 1262, 10.1126/science.165.3899.1262
Fleisch, 1970, The inhibitory effect of phosphonates on the formation of calcium phosphate crystals in vitro and on aortic and kidney calcification in vivo, Eur. J. Clin. Invest., 1, 12, 10.1111/j.1365-2362.1970.tb00591.x
Flora, 1979, Comparative antiinflammatory and bone protective effects of two diphosphonates in adjuvant arthritis, Arthritis Rheum., 22, 340, 10.1002/art.1780220405
Francis, 1969, The inhibition of calcium hydroxyapatite crystal growth by polyphosphates, Calcit. Tissue Res., 3, 151, 10.1007/BF02058658
Francis, 1969, Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo, Science, 165, 1264, 10.1126/science.165.3899.1264
Francis, 1972, The effects of disodium ethane-1-hydroxy-1,1-diphosphonate on adjuvant induced arthritis in rats, Calcif. Tissue Res., 9, 109, 10.1007/BF02061949
Fraser, 1972, The influence of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) on the development of experimentally induced urinary stones In rats, Clin. Sci., 42, 197, 10.1042/cs0420197
Gabbiani, 1966, Effect of phosphates upon experimental skin calcinosis, Can. J. Physiol. Pharmacol., 44, 203, 10.1139/y66-024
Galasko, 1980, The effect of prostaglandin synthesis inhibitors and diphosphonates on tumour-mediated osteolysis, Br. J. Surg., 67, 493, 10.1002/bjs.1800670714
Gasser, 1972, The influence of two diphosphonates on calcium metabolism in the rat, Clin. Sci., 43, 31, 10.1042/cs0430031
Gebauer, 1976, Effect of diphosphonates on adenosine 3′:5′ cyclic monophosphate in mouse calvaria after stimulation by parathyroid hormone in vitro, Clin. Sci. Mol. Med., 50, 473
Gebauer, 1980, The effect of two diphosphonates on the resorption of mouse calvaria induced by 1,25-dihydroxycholecalciferol and prostaglandin E1, in culture, Min. Electrol. Metab., 4, 172
Glimcher, 1959, Molecular biology of mineralized tissues with particular reference to bone, Rev. modern Physics, 31, 359, 10.1103/RevModPhys.31.359
Goulding, 1975, Diminished urinary excretion of cyclic AMP by rats given disodium ethane1-hydroxy-1,1-diphosphonate, J. Endocrinol., 65, 145, 10.1677/joe.0.0650145
Goulding, 1977, Comparison of effects of parathyroidectomy and ethane-l-hydroxy-1,1-diphosphonate (EHDP) administration upon bone synthesis of hydroxypro line and urinary excretion of hydroxyproline in rats, Cacif. Tissue Res., 23, 115, 10.1007/BF02012775
Guilland, 1974, The effect of two diphosphonates on the handling of calcium by rat kidney mitochondria in vitro, Calcif. Tissue Res., 15, 303, 10.1007/BF02059065
Guilland, 1974, The effect of in vivo treatment with EHDP and/or 1,25-DHCC on calcium uptake and release in isolated kidney mitochondria, Biochem. Biophys. Res. Commun., 61, 906, 10.1016/0006-291X(74)90241-1
Guilland, 1975, Stimulation of calcium absorption and apparent increased intestinal 1,25-dihydroxycholecalciferol in rats treated with low doses of ethane-l-hydroxy-1,1-diphosphonate, Clin. Sci. Mol. Med., 48, 157
Guenther, 1979, Effects of 1-hydroxyethane-1,1-diphosphonate and dichloromethane-diphosphonate on rabbit articular chondrocytes in culture, Biochem. J., 184, 203, 10.1042/bj1840203
Guenther, 1981, The effects of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on collagen synthesis by rabbit articular chondrocytes and rat bone cells, Biochem. J., 196, 293, 10.1042/bj1960293
Guenther, 1981, The influence of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on lysine hydroxylation and cross-link for mation in rat bone, cartilage and skin collagen, Biochem. J., 196, 303, 10.1042/bj1960303
Hähnel, 1973, Zum Einfluss von Diphosphonat auf die experimentelle Heparinosteopathie, Z. Alternsforsch., 27, 289
Hähnel, 1976, Anti koagulantienosteopathie durch Kumarin and deren Beeinflussung mit Diphosphonat : eine tierexperimentelle Studie, Dtsch. Gesundheitswesen, 31, 856
Hansen, 1976, Aggregation of hydroxyapatite crystals, Biochim. Biophys. Acta, 451, 549, 10.1016/0304-4165(76)90150-1
Hausmann, 1970, The concentration of inorganic pyrophosphate in human saliva and dental calculus, Arch. Oral Biol., 15, 1389, 10.1016/0003-9969(70)90029-4
Hausmann, 1972, Lipopolysaccharide-diphosphonate interaction on bone in tissue culture, Arch. Oral Biol., 17, 1381, 10.1016/0003-9969(72)90172-0
Hill, 1973, Indirect inhibition of the biosynthesis of 1,25-dihydroxycholecalciferol in rats treated with a diphosphonate, Clin. Sci., 44, 335, 10.1042/cs0440335
Hollander, 1974, Influence of the anti-calcifying agent, ethane-1hydroxy-1,1-diphosphonate (EHDP) on pre-established atheromata in rabbits, Circulation, 49, 50
Hollander, 1978, Comparative effects of cetaben (PHB) and dichloromethylene diphosphonate (Cl2MDP) on the development of atherosclerosis in the cynomolgus monkey, Atherosclerosis, 31, 307, 10.1016/0021-9150(78)90066-7
Hollander, 1979, Effects of anticalcifying and antifibrobrotic drugs on pre-established atherosclerosis in the rabbit, Atherosclerosis, 33, 111, 10.1016/0021-9150(79)90202-8
Howell, 1977, Role of proteoglycans in calcification of cartilage, Upsala J. Med. Sci., 82, 97, 10.3109/03009737709179080
Jung, 1973, The binding of pyrophosphate and two diphosphonates on hydroxyapatite crystals, Calcif. Tissue Res., 11, 269, 10.1007/BF02547227
Jowsey, 1970, Effect of sodium etidronate in adult cats, J. Lab. Clin. Med., 76, 126
Jowsey, 1973, Influence of diphosphonates on progress of experimentally induced osteoporosis, J. Lab. Clin. Med., 82, 567
King, 1971, Effect of disodium ethane-l-hydroxy-1,1-diphosphonate on bone formation, Clin. Orthop., 78, 251, 10.1097/00003086-197107000-00021
Komissarenko, 1977, Inhibition of hypersensitivity of delayed and immediate types in guinea pigs by methylenediphosphonic acid, Byull. Eksp. Biol. Med., 84, 1322, 10.1007/BF00805896
Kramsch, 1978, The effect of agents interfering with soft tissue calcification and cell proliferation on calcific fibrous fatty plaques in rabbits, Circ. Res., 42, 562, 10.1161/01.RES.42.4.562
Lane, 1973, The role diphosphonates in osteoporosis of disuse, J. Trauma, 13, 863, 10.1097/00005373-197310000-00004
Larsson, 1974, The short-term effects of high doses of ethylene-1hydroxy-1,1-diphosphonates upon early dentin formation, Calcif. Tissue Res., 16, 109, 10.1007/BF02008217
Larsson, 1976, Light microscopic and ultrastructural observations on the short-term effects of ethyiene-1-hydroxy-1,1-diphosphonate (EHDP) on rat tibia epiphysis, Acts Path. Mlcrobiof. Scand., 84, 17
Larsson, 1976, The metabolic heterogeneity of glycosaminoglycans of the different zones of the epiphyseal growth plate and the effect of ethane-l-hydroxy-1,1-diphosphonate (EHDP) upon glycosaminoglycan synthesis in vivo, Calcif. Tissue Res., 21, 67, 10.1007/BF02547384
Larsson, 1978, The effects of ethane-l-hydroxy-1, 1-diphosphonate on cellular transformation and organic matrix of the epiphyseal growth plate of the rat : a light microscopic and ultrastructural study, Acta Pathol. Microbiol. Scand., 86, 211
Larsson, 1980, In vivo distribution of 14C-labelled ethylene-1-hydroxy-1,1-diphosphonate in normal and treated young rats. An autoradiographic and ultrastructural study, Toxical. Appl. Pharmacol., 52, 391, 10.1016/0041-008X(80)90333-6
Lemkes, 1978, A new diphosphonate : dissociation between effects on cells and mineral in rats and a preliminary trial in Paget's disease, Adv. exp. Med. Biol., 103, 459, 10.1007/978-1-4684-7758-0_47
Leonard, 1979, Comparison of the effects of ethane-l-hydroxy-1,1-diphosphonate and dichloromethane diphosphonate upon periodontal bone resorption in rice rats, Arch. Oral Biol., 24, 707, 10.1016/0003-9969(79)90122-5
Matthews, 1978, Ultrastructure of calciphylaxis in skin, Metab. Bone Dis. and Rat. Res., 1, 219, 10.1016/0221-8747(78)90006-1
Mellies, 1979, Effects of etidronate disodium (EHDP) on plasma lipids and lipoproteins in familial endogenous hype rtriglyceridemia, Artery, 6, 38
Meyer, 1973, The influence of multidentate organic phosphonates on the crystal growth of hydroxyapatite, Calcif. Tissue Res., 13, 295, 10.1007/BF02015419
Meyer, 1977, The inhibition of calcium oxalate crystal growth by multidentate organic phosphonates, Calcif. Tissue Res., 23, 83, 10.1007/BF02012770
Michael, 1971, Effectiveness of diphosphonates in preventing ⪡ osteoporosis ⪢ of disuse in the rat, Clin. Orthop. Rel. Res., 78, 271, 10.1097/00003086-197107000-00022
Michael, 1972, Metabolism of disc dium ethane-l-hydroxy-1,1-diphosphonate (disodium etidronate) in the rat, rabbit, dog and monkey, Toxic Appl. Pharmacol., 21, 503, 10.1016/0041-008X(72)90007-5
Miller, 1975, Ethane-1-hydroxy-1,1-diphospho-nate (EHDP) : Effects on growth and modeling of the rat tibia, Calcif. Tissue Res., 18, 215, 10.1007/BF02546241
Miller, 1977, Ethane1-hydroxy-1,1-diphosphonate (EHDP) effects on incorporation and accumulation of osteoclast nuclei, Calcif. Tissue Res., 22, 243, 10.1007/BF02010363
Miller, 1979, The effect of dichloromethylene diphosphonate, a pyrophosphate analog, on bone and bone cell structure in the growing rat, Anat. Rec., 193, 439, 10.1002/ar.1091930309
Minkin, 1974, Bone remodelling in vitro : the effect of two diphosphonates in osteoid synthesis and bone resorption in mouse calvaria, Calcif. Tissue Res., 14, 161, 10.1007/BF02060292
Morgan, 1973, Influence of dichloromethylene diphosphonate (CI2MDP) and calcitonin on bone resorption, lactate production and phos phatase and pyrophosphatase content of mouse calvaria treated with parathyroid hormone in vitro, Calcit. Tissue Res., 13, 287, 10.1007/BF02015418
Morgan, 1975, Effects of a diphosphonate on calcium metabolism in calcium-deprived rats, Am. J. Physiol., 228, 1750, 10.1152/ajplegacy.1975.228.6.1750
Mühlbauer, 1971, The effects of diphosphonates, polyphosphates, and calcitonin on ⪡ immobilisation osteoporosis ⪢ in rats, Eur. J. Clin. Invest., 1, 336, 10.1111/j.1365-2362.1971.tb00640.x
Mühlemann, 1970, Effect of diphosphonate on human supragingival calculus, Helv. Odont. Acts, 14, 31
Neuman, 1958
Pilczyk, 1972, Effects of pyrophosphate and diphosphonates on parathyroid hormone- and fluoride-stimulated adenylate cyclase activity, FEBS Letters, 24, 225, 10.1016/0014-5793(72)80772-5
Plasmans, 1980, Influence of diphosphonate on the cellular aspect of young bone tissue, Calcif. Tissue Int., 32, 247, 10.1007/BF02408548
Potokar, 1978, The inhibitory effect of new diphosphonic acids on aortic kidney calcification in vivo, Atherosclerosis, 30, 313, 10.1016/0021-9150(78)90124-7
Rayssiguier, 1973, Etude de l'influence d'un phosphonate de sodium sur ie taux rénal de calcium chez le rat carencé en magnésium, C.R. Acad. Sci. Paris, 276, 2035
Recker, 1973, The hyperphosphatemic effect of disodium ethane-1-hydroxy-1,1-di-phosphonates (EHDPTM) : renal handling of phosphorus and the renal response to parathyroid hormone, J. Lab. Clin. Med., 81, 258
Recker, 1973, Intestinal absorption of disodium ethane-l-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique, Toxic Appl. Pharmacol., 24, 580, 10.1016/0041-008X(73)90219-6
Reitemeyer, 1940, The inhibiting action of minute amounts of sodium hexametaphosphate on the precipitation of calcium carbonate from ammoniacal solutions, J. Phys. Chem., 44, 535, 10.1021/j150401a001
Reitsma, 1980, Kinetic studies of bone and mineral metabolism during treatment with (3-amino-l-hydroxypropyl idene)-1,1-bisphosphonate (APD) in rats, Calcif. Tissue Int., 32, 145, 10.1007/BF02408534
Reynolds, 1972, The effect of two diphosphonates on the resorption of mouse calvaria in vitro, Calcif. Tissue Res., 10, 302, 10.1007/BF02012561
Reynolds, 1973, Inhibition by diphosphonates of bone resorption in mice and comparison with grey lethal osteopetrosis, Calcif. Tissue Res., 12, 59, 10.1007/BF02013722
Robertson, 1972, The effects of diphosphonates on the exchangeable and nonexchangeable calcium and phosphate of hydroxyapatite, Biochim. Biophys. Acta, 261, 517, 10.1016/0304-4165(72)90076-1
Robertson, 1973, Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro, Clin. Chim. Acts, 43, 31, 10.1016/0009-8981(73)90114-9
Rosenblum, 1974, The effects of disodium ethane-1-hydroxy-1, 1-diphosphonate (EHDP) on bone and serum chemistry in rabbits, Calcif. Tissue Res., 16, 145, 10.1007/BF02008220
Rosenblum, 1975, The effect of disodium ethane-l-hydroxy-1,1-diphosphonate (EHDP) on a rabbit model of athero-arteriosclerosis, Atherosclerosis, 22, 411, 10.1016/0021-9150(75)90021-0
Rosenblum, 1977, The effects of various diphosphonates on a rat model of cardia calciphylaxis, Calcif. Tissue Res., 23, 151, 10.1007/BF02012781
Rosenquist, 1978, Resorption of bone implants, Int. J. Oral Surg., 7, 7, 10.1016/S0300-9785(78)80003-9
Rowe, 1976, The alteration of osteoclast morphology by diphosphonate in bone organ culture, Calcit. Tissue Res., 20, 53, 10.1007/BF02546397
Russell, 1964, Urinary pyrophosphate and urolithiasis, Lancet, i, 1446, 10.1016/S0140-6736(64)92014-8
Russell, 1965, Excretion of inorganic pyrophosphate in hypophosphatasia, Lancet, ii, 461, 10.1016/S0140-6736(65)91422-4
Russell, 1970, Inorganic pyrophosphate in the plasma, urine and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout), Lancet, ii, 899, 10.1016/S0140-6736(70)92070-2
Russell, 1970, The influence of pyrophosphate, condensed phosphates, phosphonates and other phosphate compounds on the dissolution of hydroxyapatite in vitro and on bone resorption Induced by parathyroid hormone in tissue culture and in thyroparathyroidectomised rats, Calcif. Tissue Res., 6, 183, 10.1007/BF02196199
Russell, 1971, Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta and other disorders of bone, J. Clin. Invest., 50, 961, 10.1172/JCI106589
Russell, 1973, Effect of diphosphonates on calcitonin on the chemistry and quantitative histology of rat bone, Calcif. Tissue Res., 11, 179, 10.1007/BF02547218
Russell, 1975, Experimental renal osteodystrophy : the response to 25-hydroxycholecalciferol and dichloromethylene diphosphate therapy, J. Clin. Invest., 56, 548, 10.1172/JCI108123
Schibler, 1966, Inhibition of skin calcification (calciphylaxis) by polyphosphates, Experientia, 22, 367, 10.1007/BF01901138
Schibler, 1968, inhibition of pyrophosphate and polyphosphate of aortic calcification induced by vitamin D3 in rats, Clin. Sci., 35, 363
Schenk, 1973, Effect of ethane-l-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (CI2MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats, Calcif. Tissue. Res., 11, 196, 10.1007/BF02547219
Shinoda, 1979, Structure-activity relationship of diphosphonates with alkyl groups of various length, Min. Electrol. Metab., 2, 268
Trechsel, 1977, Relation between bone mineralization, Ca absorption, and plasma Ca in phosphonate-treated rats, Am. J. Physiol., 232, E298
Trechsel, 1979, Regulation of the metabolism of 25-hydroxyvitamin D3 in primary cultures of chick kidney cells, J. Clin. Invest., 64, 206, 10.1172/JCI109441
Trechsel U., Taylor C.M., Eisman J.A., Bonjour J.-P., Fleisch H. : Plasma levels of vitamin D metabolites in diphosphonate-treated rats. Clin. Sci., in press.
Troehler, 1975, Renal secretion of diphosphonates in rats, Kidney Int., 8, 6, 10.1038/ki.1975.70
Veltischev, 1978, Antlmutagenic effect of a hydroxyethylidendiphosphonic acid derivative, Genetika, 14, 1276
Wasserman, 1973, Ileal absorption of disodium ethane-l-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethylene diphosphonate (CI2MDP) in the chick, Experientia, 29, 1110, 10.1007/BF01946749
Weisbrode, 1978, Effect of dichloromethylene diphosphonate on morphology, enzyme activity, and ash content of bones of thyroparathyroidectomized rats, Calcit. Tissue Res., 25, 119, 10.1007/BF02010760
Yarrington, 1976, Experimental parturient hypocalcemia in cows following prepartal chemical inhibition of bone resorption, Am. J. Pathol., 83, 569
Yarrington, 1977, Effect of dichloromethane diphosphonate on calcium homeostasis mechanisms in pregnant cows, Am. J. Pathol., 87, 615
Yarrington, 1977, Effect of ethane-l-hydroxy-1,1-diphisphonate (EHDP) on the ultrastructure of parathyroid glands and plasma immunoreactive parathyroid hormone in pregnant cows fed a low calcium diet, Lab. Invest., 36, 402
Zemskov, 1979, Intensification of antibacterial, antiviral insusceptibility and immune response by the oficinal RNA preparation, Byull. Eksp. Blot. Med., 6, 259