Differential Participation of Central L-Glutamate Receptors of non-NMDA-Subtype in Associative Learning of the Honeybee Apis mellifera
Tóm tắt
Participation of non-NMDA-receptors in associative learning in the honeybee was analyzed using a complex approach. There were studied effects of systemic and intracerebral AMPA injections on retention of the elaborated conditional reflex in short-term memory, on dynamics of the bioelectrical activity of neurons of calyx of the mushroom bodies, and on the limb locomotor activity. It has been shown that the systemic and intracerebral AMPA injections stimulate processes of short-term memory and activate bioelectrical activity of neurons of the mushroom body medial calyx. Antagonist of AMPA-receptors NS-257 HCl suppressed spontaneous activity of these neurons. The observed processes did not depend on the character of locomotor activity. These results confirm the hypothesis proposed earlier about involvement of non-NMDA-receptors in the process of associative learning.
Tài liệu tham khảo
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