Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies

Clinical Pharmacology and Therapeutics - Tập 89 Số 1 - Trang 65-74 - 2011
Dominick J. Angiolillo1, C. Michael Gibson2, Shuk Han Cheng3, Céline Ollier4, Olivier Nicolas4, L. Bergougnan5, Laurent Perrin6, Frank LaCreta7, Fabrice Hurbin4, M. Dubar5
1Division of Cardiology, University of Florida College of Medicine, Jacksonville, Florida, USA
2Division of Cardiology, Beth Israel–Deaconess Medical Center, Boston, Massachusetts, USA;
3Clinical and Exploratory Pharmacology sanofi‐aventis Bridgewater New Jersey USA
4Global Metabolism and Pharmacokinetic Department sanofi‐aventis Recherche Développement Montpellier France
5Clinical Pharmacology and Exploratory Department sanofi‐aventis Recherche Développement Chilly Mazarin France
6Biostatistics Department Sanofi‐aventis Recherche Développement Montpellier France
7Discovery Medicine and Clinical Pharmacology Bristol-Myers Squibb Princeton New Jersey USA

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