Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease

Younossi, 2019, Non-alcoholic fatty liver disease — a global public health perspective, J Hepatol, 70, 531, 10.1016/j.jhep.2018.10.033

Bellentani, 2017, Is it time to change NAFLD and NASH nomenclature?, Lancet Gastroenterol Hepatol, 2, 547, 10.1016/S2468-1253(17)30146-2

Wong, 2015, Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States, Gastroenterology, 148, 547, 10.1053/j.gastro.2014.11.039

Italian Association for the Study of the L, 2017, AISF position paper on nonalcoholic fatty liver disease (NAFLD): updates and future directions, Dig Liver Dis, 49, 471, 10.1016/j.dld.2017.01.147

Bellanti, 2017, Lipid oxidation products in the pathogenesis of non-alcoholic steatohepatitis, Free Radic Biol Med, 111, 173, 10.1016/j.freeradbiomed.2017.01.023

Weiskirchen, 2018, Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts, F1000Research, 7, 10.12688/f1000research.14841.1

Marra, 2018, Lipotoxicity and the gut-liver axis in NASH pathogenesis, J Hepatol, 68, 280, 10.1016/j.jhep.2017.11.014

Salomone, 2013, Unconjugated bilirubin, a potent endogenous antioxidant, is decreased in patients with non-alcoholic steatohepatitis and advanced fibrosis, J Gastroenterol Hepatol, 28, 1202, 10.1111/jgh.12155

Mansouri, 2018, Mitochondrial dysfunction and signaling in chronic liver diseases, Gastroenterology, 155, 629, 10.1053/j.gastro.2018.06.083

Romero-Gomez, 2017, Treatment of NAFLD with diet, physical activity and exercise, J Hepatol, 67, 829, 10.1016/j.jhep.2017.05.016

Lirussi, 2007, Antioxidant supplements for non-alcoholic fatty liver disease and/or steatohepatitis, Cochrane Database Syst Rev, CD004996

El Hadi, 2018, Vitamin E as a treatment for nonalcoholic fatty liver disease: reality or myth?, Antioxidants, 7

Gee, 2011, Unleashing the untold and misunderstood observations on vitamin E, Genes Nutr, 6, 5, 10.1007/s12263-010-0180-z

Chen, 2016, Micronutrient antioxidants and nonalcoholic fatty liver disease, Int J Mol Sci, 17, 10.3390/ijms17091379

Phung, 2009, Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis, Int J Mol Med, 24, 171

Nan, 2009, Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice, Scand J Gastroenterol, 44, 1121, 10.1080/00365520903114912

Sanyal, 2010, Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis, N Engl J Med, 362, 1675, 10.1056/NEJMoa0907929

Lavine, 2011, Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial, JAMA, 305, 1659, 10.1001/jama.2011.520

Pietu, 2012, Ursodeoxycholic acid with vitamin E in patients with nonalcoholic steatohepatitis: long-term results, Clin Res Hepatol Gastroenterol, 36, 146, 10.1016/j.clinre.2011.10.011

Foster, 2011, Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial, Am J Gastroenterol, 106, 71, 10.1038/ajg.2010.299

Dufour, 2006, Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis, Clin Gastroenterol Hepatol, 4, 1537, 10.1016/j.cgh.2006.09.025

Nobili, 2008, Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease: a randomized, controlled trial, Hepatology, 48, 119, 10.1002/hep.22336

National Academy of Sciences, 2011

Wei, 2016, Association between dietary vitamin C intake and non-alcoholic fatty liver disease: a cross-sectional study among middle-aged and older adults, PLoS One, 11

Han, 2014, Associations between intakes of individual nutrients or whole food groups and non-alcoholic fatty liver disease among Korean adults, J Gastroenterol Hepatol, 29, 1265, 10.1111/jgh.12520

Da Silva, 2014, A cross-sectional study assessing dietary intake and physical activity in Canadian patients with nonalcoholic fatty liver disease vs healthy controls, J Acad Nutr Diet, 114, 1181, 10.1016/j.jand.2014.01.009

Madan, 2006, Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD), J Clin Gastroenterol, 40, 930, 10.1097/01.mcg.0000212608.59090.08

Chan, 2015, Diet-quality scores and prevalence of nonalcoholic fatty liver disease: a population study using proton-magnetic resonance spectroscopy, PLoS One, 10, 10.1371/journal.pone.0139310

Zelber-Sagi, 2018, High red and processed meat consumption is associated with non-alcoholic fatty liver disease and insulin resistance, J Hepatol, 68, 1239, 10.1016/j.jhep.2018.01.015

2016, EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease, J Hepatol, 64, 1388, 10.1016/j.jhep.2015.11.004

Wilett, 1998

Keinan-Boker, 2005, Overweight and obesity prevalence in Israel: findings of the first national health and nutrition survey (MABAT), Isr Med Assoc J, 7, 219

Zelber-Sagi, 2007, Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): a population based study, J Hepatol, 47, 711, 10.1016/j.jhep.2007.06.020

Munteanu, 2016, Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference, Aliment Pharmacol Ther, 44, 877, 10.1111/apt.13770

Poynard, 2018, Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference, Eur J Gastroenterol Hepatol, 30, 569, 10.1097/MEG.0000000000001064

Poynard, 2011, Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age, BMC Gastroenterol, 11, 39, 10.1186/1471-230X-11-39

Morra, 2009, FibroMAX™: towards a new universal biomarker of liver disease?, Future Drugs Ltd, 7, 481

U.S. Department of health and human services, 2003

Ahuja, 2004, Current status of vitamin E nutriture, Ann N Y Acad Sci, 1031, 387, 10.1196/annals.1331.052

Oddy, 2013, The Western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescence, Am J Gastroenterol, 108, 778, 10.1038/ajg.2013.95

Zelber-Sagi, 2017, The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: evidence and plausible mechanisms, Liver Int, 37, 936, 10.1111/liv.13435

Vos, 2012, Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD, J Pediatr Gastroenterol Nutr, 54, 90, 10.1097/MPG.0b013e318229da1a

Vilar-Gomez, 2018, Vitamin E improves transplant-free survival and hepatic decompensation among patients with nonalcoholic steatohepatitis and advanced fibrosis, Hepatology

Fernando Bril, 2019, Role of Vitamin E for Nonalcoholic Steatohepatitis in Patients with Type 2 Diabetes: a randomized controlled trial, Diabetes Care

Miller, 2005, Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality, Ann Intern Med, 142, 37, 10.7326/0003-4819-142-1-200501040-00110

Schurks, 2010, Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials, BMJ, 341, 10.1136/bmj.c5702

Klein, 2011, Vitamin e and the risk of prostate cancer: the selenium and vitamin e Cancer prevention trial (SELECT), JAMA, 306, 1549, 10.1001/jama.2011.1437

Harrison, 2003, Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis, Am J Gastroenterol, 98, 2485, 10.1111/j.1572-0241.2003.08699.x

Guy, 2015, Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity, Hepatology, 61, 98, 10.1002/hep.27235

Salamone, 2012, Moro orange juice prevents fatty liver in mice, World J Gastroenterol, 18, 3862, 10.3748/wjg.v18.i29.3862

Bedogni, 2014, Epidemiology of fatty liver: an update, World J Gastroenterol, 20, 9050

Ballestri, 2017, Ultrasonographic fatty liver indicator detects mild steatosis and correlates with metabolic/histological parameters in various liver diseases, Metab Clin Exp, 72, 57, 10.1016/j.metabol.2017.04.003

Ballestri, 2017, NAFLD as a sexual dimorphic disease: role of gender and reproductive status in the development and progression of nonalcoholic fatty liver disease and inherent cardiovascular risk, Adv Ther, 34, 1291, 10.1007/s12325-017-0556-1