Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial

The Lancet - Tập 388 Số 10055 - Trang 2004-2014 - 2016
P. Mulvenna1, Matthew Nankivell2, Rachael Barton3, C. Faivre‐Finn4, P. Wilson5, Elaine McColl6, Barbara Moore7, I. Brisbane8, David Ardron9, Tanya Holt10,11, S. Morgan12, Caroline Lee13, Kathryn Waite14, N. Bayman4, Cheryl Pugh2, Benjamin Sydes2, Richard Stephens2, Mahesh Parmar2, Ruth E. Langley2
1Northern Centre for Cancer Care, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
2Medical Research Council Clinical Trials Unit at University College London, London, UK
3Queen’s Centre for Oncology and Haematology, Castle Hill Hospital, Hull, UK
4Institute of Cancer Sciences, The University of Manchester, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, UK
5Bristol Haematology and Oncology Centre, Bristol, UK
6Newcastle Clinical Trials Unit and Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
7Wales Cancer Research Network, Cardiff UK
8The Beatson West of Scotland Cancer Centre, Greater Glasgow Health Board and Clyde, Glasgow, UK
9Patient representative, Manchester, UK
10Trans Tasman Radiation Oncology Group, Waratah, NSW, Australia
11University of Queensland, QLD, Australia
12Nottingham University Hospital, Nottingham, UK
13Weston Park Hospital, Sheffield, UK
14Queen Elizabeth Hospital, Kings Lynn, UK

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