Determination versus differentiation and the MyoD family of transcription factors

Biochemistry and Cell Biology - Tập 73 Số 9-10 - Trang 723-732 - 1995
Lynn A. Megeney1, Michael A. Rudnicki
1Institute for Molecular Biology and Biotechnology, McMaster University, Hamilton, ON, Canada.

Tóm tắt

The myogenic regulatory factors (MRFs) form a family of basic helix–loop–helix transcription factors consisting of Myf-5, MyoD, myogenin, and MRF4. The MRFs play key regulatory roles in the development of skeletal muscle during embryogenesis. Sequence homology, expression patterns, and genetargeting experiments have revealed a two-tiered subclassification within the MRF family. Myf-5 and MyoD are more homologous to one another than to the others, are expressed in myoblasts before differentiation, and are required for the determination or survival of muscle progenitor cells. By contrast, myogenin and MRF4 are more homologous to one another than to the others and are expressed upon differentiation, and myogenin is required in vivo as a differentiation factor while the role of MRF4 remains unclear. On this basis, MyoD and Myf-5 are classified as primary MRFs, as they are required for the determination of myoblasts, and myogenin and MRF4 are classified as secondary MRFs, as they likely function during terminal differentiation.Key words: MyoD, Myf-5, myogenin, MRF4, skeletal muscle.

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Tài liệu tham khảo

Atchley W.R., 1994, Proc. Natl. Acad. Sci. U.S.A., 91, 11522, 10.1073/pnas.91.24.11522

Benezra R., 1990, Cell, 61, 49, 10.1016/0092-8674(90)90214-Y

Blanar M.A., 1994, J. Cell. Biochem., 104, 475

Bober E., 1991, J. Cell Biol., 113, 1255, 10.1083/jcb.113.6.1255

Bober E., 1994, Development (Cambridge), 120, 603, 10.1242/dev.120.3.603

Brand-Saberi B., 1993, Anat. Embryol., 188, 239, 10.1007/BF00188215

Braun T., 1994, Dev. Biol., 164, 24, 10.1006/dbio.1994.1177

Braun T., 1995, EMBO J., 14, 11761186, 10.1002/j.1460-2075.1995.tb07101.x

Braun T., 1990, EMBO J., 9, 821, 10.1002/j.1460-2075.1990.tb08179.x

Braun T., 1992, Cell, 71, 369, 10.1016/0092-8674(92)90507-9

Braun T., 1994, Development (Cambridge), 120, 3083, 10.1242/dev.120.11.3083

Buckingham M., 1994, Cum Biol., 4, 61, 10.1016/S0960-9822(00)00014-2

Buffinger N., 1994, Development (Cambridge), 120, 1443, 10.1242/dev.120.6.1443

Burgess R., 1995, Dev. Biol., 168, 296, 10.1006/dbio.1995.1081

Caruso M., 1993, Oncogene, 8, 267

Christ B., 1992, Anat. Embryol., 186, 505, 10.1007/BF00185464

Corneliussen B., 1991, J. Virol., 65, 6084, 10.1128/JVI.65.11.6084-6093.1991

Cossu G., 1987, Cum Top. Dev. Biol., 23, 185, 10.1016/S0070-2153(08)60625-0

Cossu G., 1995, Proc. Natl. Acad. Sci. U.S.A., 92, 2254, 10.1073/pnas.92.6.2254

Crow M.T., 1986, Dev. Biol., 113, 238, 10.1016/0012-1606(86)90126-0

Davies R.L., 1987, Cell, 51, 987, 10.1016/0092-8674(87)90585-X

Dimario J.X., 1993, Nature (London), 362, 165, 10.1038/362165a0

Echelard Y., 1993, Cell, 75, 1417, 10.1016/0092-8674(93)90627-3

Edmondson D.G., 1994, Development (Cambridge), 120, 1251, 10.1242/dev.120.5.1251

Emerson C.P., 1993, Curr. Opin. Gen. Dev., 3, 265, 10.1016/0959-437X(93)90033-L

Falcone G., 1991, Mol. Cell. Biol., 11, 3331, 10.1128/MCB.11.6.3331

Fan C.-M., 1994, Cell, 79, 1, 10.1016/0092-8674(94)90393-X

Franz T., 1993, Anat. Embryol., 187, 153

Fuchtbauer E.-M., 1992, Dev. Dyn., 193, 34, 10.1002/aja.1001930106

Goldhammer D.J., 1995, Development (Cambridge), 121, 637, 10.1242/dev.121.3.637

Goulding M.D., 1991, EMBO J., 10, 1135, 10.1002/j.1460-2075.1991.tb08054.x

Griesharnrner U., 1992, Cell, 69, 79, 10.1016/0092-8674(92)90120-2

Gruss P., 1992, Cell, 69, 719, 10.1016/0092-8674(92)90281-G

Gurdon J.B., 1992, Semin. Dev. Biol., 3, 255

Hasty P., 1993, Nature (London), 364, 501, 10.1038/364501a0

Henthorn P., 1990, Nucleic Acids Res., 18, 677, 10.1093/nar/18.3.677

Holtzer H., 1953, J. Exp. Zool., 123, 335, 10.1002/jez.1401230206

Hughes S.M., 1993, Development (Cambridge), 118, 1137, 10.1242/dev.118.4.1137

Johnson R.L., 1994, Cell, 79, 1165, 10.1016/0092-8674(94)90008-6

Kenny-Mobbs T., 1987, Development (Cambridge), 100, 449, 10.1242/dev.100.3.449

Kopan R., 1994, Development (Cambridge), 120, 2385, 10.1242/dev.120.9.2385

Krumlauf R., 1994, Cell, 78, 191, 10.1016/0092-8674(94)90290-9

Langman J., 1968, J. Embryol. Exp. Morphol., 19, 217

Lassar A.B., 1986, Cell, 47, 649, 10.1016/0092-8674(86)90507-6

Li L., 1992, Cell, 71, 1181, 10.1016/S0092-8674(05)80066-2

Martelli F., 1994, Oncogene, 9, 3579

Miller J.B., 1986, J. Cell. Biol., 103, 2197, 10.1083/jcb.103.6.2197

Miner J.H., 1991, Mol. Cell. Biol., 11, 2842, 10.1128/MCB.11.5.2842

Montarras D., 1991, New Biol., 3, 592

Munsterberg A.E., 1995, Development (Cambridge), 121, 651, 10.1242/dev.121.3.651

Murre C., 1989, Cell, 56, 777, 10.1016/0092-8674(89)90682-X

Murre C., 1989, Cell, 58, 537, 10.1016/0092-8674(89)90434-0

Muskavitch M.A., 1994, Dev. Biol., 166, 415430, 10.1006/dbio.1994.1326

Nabeshima Y., 1993, Nature (London), 364, 532, 10.1038/364532a0

Naidu P.S., 1995, Mol. Cell. Biol., 15, 2707, 10.1128/MCB.15.5.2707

Olson E.N., 1992, Dev. Biol., 154, 261, 10.1016/0012-1606(92)90066-P

Olson E.N., 1994, Genes & Dev., 8, 1, 10.1101/gad.8.1.1

Olson E.N., 1994, Cell, 79, 9, 10.1016/0092-8674(94)90395-6

Olson E.N., 1987, Mol. Cell. Biol., 7, 2104, 10.1128/MCB.7.6.2104

Ordahl C.P., 1992, Development (Cambridge), 114, 339, 10.1242/dev.114.2.339

Patapoutian A., 1993, Development (Cambridge), 118, 61, 10.1242/dev.118.1.61

Pette D., 1990, Rev. Physiol. Biochem. Pharmacol., 116, 1

Pette D., 1985, Muscle & Nerve, 8, 676, 10.1002/mus.880080810

Pourquie O., 1993, Proc. Natl. Acad. Sci. U.S.A., 90, 5242, 10.1073/pnas.90.11.5242

Pownall M.E., 1992, Semin. Dev. Biol., 3, 229

Riddle R.D., 1993, Cell, 75, 1401, 10.1016/0092-8674(93)90626-2

Roelink H., 1994, Cell, 76, 761, 10.1016/0092-8674(94)90514-2

Rong P.M., 1992, Development (Cambridge), 115, 657, 10.1242/dev.115.3.657

Rudnicki M.A., 1995, BioEssays, 17, 203, 10.1002/bies.950170306

Rudnicki M.A., 1990, Dev. Biol., 138, 348, 10.1016/0012-1606(90)90202-T

Rudnicki M.A., 1992, Cell, 71, 383, 10.1016/0092-8674(92)90508-A

Rudnicki M.A., 1993, Cell, 75, 1351, 10.1016/0092-8674(93)90621-V

Skerjanc I.S., 1994, Mol. Cell. Biol., 14, 8451, 10.1128/MCB.14.12.8451

Smith C.K., 1994, J. Cell. Physiol., 159, 379, 10.1002/jcp.1041590222

Smith T.H., 1994, J. Cell Biol., 127, 95, 10.1083/jcb.127.1.95

Stockdale F.E., 1992, Dev. Biol., 154, 284, 10.1016/0012-1606(92)90068-R

Tapscott S.J., 1992, Mol. Cell. Biol., 12, 4994, 10.1128/MCB.12.11.4994

Taylor L.D., 1989, J. Cell Biol., 108, 533, 10.1083/jcb.108.2.533

Venuti J.M., 1995, J. Cell Biol., 128, 563, 10.1083/jcb.128.4.563

Vivarelli E., 1986, Dev. Biol., 117, 319, 10.1016/0012-1606(86)90374-X

Weintraub H., 1993, Cell, 75, 1241, 10.1016/0092-8674(93)90610-3

Williams B.A., 1994, Development (Cambridge), 120, 785, 10.1242/dev.120.4.785

Yablonka-Reuveni Z., 1994, Dev. Biol., 164, 588, 10.1006/dbio.1994.1226

Zhang W., 1995, Genes & Dev., 9, 1388, 10.1101/gad.9.11.1388

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Biochemistry and Cell Biology

Tập 73 Số 9-10

723-732

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