Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015

Eurosurveillance - Tập 20 Số 49 - 2015
Henrik Hasman1, Anette M. Hammerum1, Frank Hansen1, René S. Hendriksen2, Bente Olesen3, Yvonne Agersø2, Ea Zankari2, Pimlapas Leekitcharoenphon2, Marc Stegger1,4, Rolf Sommer Kaas2, Lina Cavaco2, Dennis Schrøder Hansen3, Frank M. Aarestrup2, Robert Skov1
1Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark
2National Food Institute, Technical University of Denmark, Lyngby, Denmark
3Department of Clinical Microbiology, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark
4Pathogen Genomics Division, Translational Genomics Research Institute (TGen), Flagstaff, Arizona, USA

Tóm tắt

The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat. One isolate from chicken meat belonged to the epidemic spreading sequence type ST131. In addition to IncI2*, an incX4 replicon was found to be linked to mcr-1. This report follows a recent detection of mcr-1 in E. coli from animals, food and humans in China.

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Tài liệu tham khảo

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Tập 20 Số 49

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