Detection of KPC in Acinetobacter spp. in Puerto Rico

Antimicrobial Agents and Chemotherapy - Tập 54 Số 3 - Trang 1354-1357 - 2010
Iraida E. Robledo1,2, Edna E. Aquino1,2, María I. Santé1,3, Jorge Santana1, Diana M. Otero1, Carlos F. León1, Guillermo J. Vázquez1,2
1Puerto Rico Antibiotic Resistance Study Group, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico
2University of Puerto Rico, School of Medicine, Department of Microbiology and Medical Zoology
3University of Puerto Rico, School of Medicine, Department of Pathology and Laboratory Medicine

Tóm tắt

ABSTRACT During an island-wide PCR-based surveillance study of beta-lactam resistance in multidrug-resistant (MDR) Escherichia coli , Klebsiella pneumoniae , Pseudomonas aeruginosa , and Acinetobacter calcoaceticus-baumannii complex isolates obtained from 17 different hospitals, 10 KPC-positive Acinetobacter isolates were identified. DNA sequencing of the bla KPC gene identified KPC-2, -3, and -4 and a novel variant, KPC-10. This is the first report of a KPC-type beta-lactamase identified in Acinetobacter species.

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