Dermatofibrosarcoma Protuberans of the Breast

Tumori - Tập 94 Số 6 - Trang 861-863 - 2008
Jong-Yueh Lin1, Shyr‐Ming Sheen‐Chen1, Wayne Hsu1, Tsao-Cheng Huang2, Sheung-Fat Ko3, Hock-Liew Eng3
1Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center College of Medicine, Chang Gung University, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan.
2Department of Pathology, Chang Gung Memorial Hospital, Kaohsiung Medical Center College of Medicine, Chang Gung University, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan
3Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center College of Medicine, Chang Gung University, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan

Tóm tắt

BackgroundDermatofibrosarcoma protuberans is an uncommon, locally aggressive but rarely metastasizing tumor of the deep dermis and subcutaneous tissue. It may occur at almost any site but is most common in the trunk and extremities. Dermatofibrosarcoma protuberans of the breast has been rarely reported.Case PresentationA 49-year-old woman without a significant medical history presented with a right breast mass that had been present for more than 10 years. Recently, progressive enlargement of the mass was noted. Physical examination showed a firm, well-defined, non-tender, mobile, erythematous 2 × 2 cm mass in the upper outer part of the right breast. Breast sonography showed a 2.3 × 1 cm slightly heteroechoic nodule with uneven anterior contours located in the dermal layer, highly suggestive of a dermal lesion. Wide excision of the mass was performed. Microscopically, the hypercellular tumor was composed of relatively monomorphic spindle cells forming a storiform pattern around the sweat glands of the deep dermis and the subcutaneous fat vacuoles. The tumor cells showed strong immunoreactivity for CD34. The final histological diagnosis was dermatofibrosarcoma protuberans.ConclusionsDermatofibrosarcoma protuberans of the breast, though uncommon, does exist. With the awareness of this entity can a prompt diagnosis be made and the disease be properly managed.

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Thông tin
Thông tin xuất bản

Tumori

Tập 94 Số 6

861-863

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