Depressed PPD and tetanus toxoid presentation by monocytes to T lymphocytes in patients with rheumatoid arthritis: restoration by interferon gamma

Smiley J, Sachs C, Ziff M (1968) In vitro synthesis of immunoglobulin by rheumatoid synovial membrane. J Clin Invest 47:624?629

Munthe E, Natvig JB (1972) Immunoglobulin classes, subclasses and complexes of IgG rheumatoid factor in rheumatoid plasma cells. Clin Exp Immunol 12:55?63

Meijer CJAM, van de Putte LBA, Eulderink F, Kleinjan R, Lafeber G, Bots GTAM (1977) Characteristics of mononuclear cell populations in chronically inflamed synovial membranes. J Pathol 12:1?7

Janossy G, Duke O, Poulter LW, Panayi G, Bofill M, Goldstein G (1981) Rheumatoid arthritis: a disease of T-lymphocyte/macrophage immunoregulation. Lancet II:839?842

Duke, O, Panayi S, Janossy G, Poulter LW (1982) An immunohistological analysis of lymphocyte subpopulations and their microenvironment in the synovial membranes of patients with rheumatoid arthritis using monoclonal antibodies. Clin Exp Immunol 49:22?30

Klareskog L, Forsum U, Malmnös Tjernlund U, Kabelitz D, Wigren A (1981) Appearance of anti-HLA-DR reactive cells in normal and rheumatoid synovial tissue. Scand J Immunol 14:183?189

Burmester GR, Dimitriu-Bona A, Waters SJ, Winchester R (1983) Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens associated with monocytes/macrophages and fibroblasts. Scand J Immunol 17:69?82

Steinman RM, Kaplan G, Witmer MD, Cohn ZA (1979) Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers and maintenance in vitro. J Exp Med 149:1

Seitz M, Vogt P, Müller W, Hunstein W, Gemsa D (1983) Characterization of blood mononuclear cells of rheumatoid arthritis patients. II. Depressed PPD presentation by monocytes to T lymphocytes. Clin Immunol Immunopathol 29:242?253

Seitz M, Deimann W, Gram N, Hunstein W, Gemsa D (1982) Characterization of blood mononuclear cells of rheumatoid arthritis patients. I. Depressed lymphocyte proliferation and enhanced prostanoid release from monocytes. Clin Immunol Immunopathol 25:405?416

Koski JR, Poplak DG, Blease RMA (1976) Nonspecific esterase stain for the identification of monocytes and macrophages. In: Bloom CBR, David JR (eds) In vitro methods in cell mediated and tumor immunity. Academic Press, New York, p 359

Deimann W, Seitz M, Gemsa D, Fahimi HD (1984) Endogenous peroxidase in the nuclear envelope and endoplasmic reticulum of monocytes in vitro: association with arachidonic acid metabolism. Blood 64:491?498

Gemsa D, Woo DH, Fudenberg HH, Schmid R (1973) Erythrocyte catabolism by macrophages in vitro. The effect of hydrocortisone in erythrophagocytosis and the induction of hemeoxygenase. J Clin Invest 52:812?822

Papamichail M, Holborow EJ, Ketz HJ, Currey HLF (1972) Subpopulations of human peripheral blood lymphocytes distinguished by combined rosette formation and membrane immunofluorescence. Lancet II:64?65

Gillis S, Watson J (1980) Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin-2 producing human leukemia T cell line. J Exp Med 152:1709?1719

Basham TY, Merigan TC (1983) Recombinant interferon gamma increases HLA-DR synthesis and expression. J Immunol 130:1492?1498

Winchester RJ, Burmester GR (1981) Demonstration of Ia antigens on certain dendritic cells and on a novel elongate cell found in human synovial tissues. Scand J Immunol 14:441?446

Seitz M, Napierski J, Augustin R, Hunstein W, Kirchner H (1987) Reduced production of interferon alpha and interferon gamma in leukocyte cultures from patients with active rheumatoid arthritis. Scand J Rheumatol 16:257?262

Hasler F, Bluestein H-G, Zvaifler N, Epstein LB (1983) Analysis of the defects responsible for impaired regulation of the EBV-induced B-cell proliferation by rheumatoid arthritis lymphocytes. I. Diminshed gamma interferon production in response to autologous stimulation. J Exp Med 157:173?188

Lemmel EM, Franke M, Gaus W, Hartl PW, Hofschneider PH, Miehlke K, Machalke K, Obert HJ (1987) Results of a phase II clinical trial on treatment of rheumatoid arthritis with recombinant interferon gamma. Rheumatol Int 7:127?132

Obert HJ, Hofschneider PH (1985) Interferon bei chronischer Polyarthritis. Dtsch Med Wochenschr 46:1766?1769

Seitz M, Manz G, Frank M (1986) Einsatz von rekombinantem human-Interferon gamma bei Patienten mit rheumatoider Arthritis. Z Rheumatol 45:93?99