Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade glioma

Abhishek D. Garg1, Lien Vandenberk2, Carolien Koks2, Tina Verschuere3, Louis Boon4, Stefaan Van Gool2, Patrizia Agostinis1
1Cell Death Research and Therapy Laboratory, Department of Cellular and Molecular Medicine, Katholieke Universiteit (KU) Leuven, Leuven 3000, Belgium.
2Laboratory of Pediatric Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven 3000, Belgium.
3Department of Neurosciences, Research Group—Neuroanatomy and Neurosurgery, KU Leuven, Leuven 3000, Belgium.
4EPIRUS Biopharmaceuticals Netherlands BV, 3584 Utrecht, Netherlands.

Tóm tắt

Combining an immunogenic cell death inducer with dendritic cell immunotherapy treats high-grade glioma in a preclinical model.

Từ khóa


Tài liệu tham khảo

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