Delivery of a Healthy Baby After First-Trimester Maternal Exposure to Lapatinib

Burris, 2005, Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas, J Clin Oncol, 23, 5305, 10.1200/JCO.2005.16.584 Romond Perez Piccart-Gebhart Watson, 2005, Herceptin (trastuzumab) therapy during pregnancy: association with reversible anhydramnios, Obstet Gynecol, 105, 642, 10.1097/01.AOG.0000141570.31218.2b Gywn Berry, 1999, Management of breast cancer during pregnancy using a standardized protocol, J Clin Oncol, 17, 855, 10.1200/JCO.1999.17.3.855 Gywn, 2001, Breast cancer during pregnancy, Oncology, 15, 39 Ebert, 1997, Cytotoxic therapy and pregnancy, Pharmacol Ther, 74, 207, 10.1016/S0163-7258(97)82004-9 Gonzalez-Angulo, 2004, Paclitaxel chemotherapy in a pregnant patient with bilateral breast cancer, Clin Breast Cancer, 5, 317, 10.3816/CBC.2004.n.037 De Santis, 2000, Metastatic breast cancer in pregnancy: first case of chemotherapy with docetaxel, Eur J Cancer Care (Engl), 9, 235, 10.1046/j.1365-2354.2000.00231.x Miettinen, 1999, Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure, Nat Genet, 22, 69, 10.1038/8773 Miettinen, 1995, Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor, Nature, 376, 337, 10.1038/376337a0 Yoshimura, 2000, Effect of epidermal growth factor on lung growth in experimental fetal pulmonary hypoplasia, Early Hum Dev, 57, 61, 10.1016/S0378-3782(99)00052-3 Burrows, 1997, Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex, Neuron, 19, 251, 10.1016/S0896-6273(00)80937-X Kee, 1997, Receptor protein tyrosine kinases in perinatal developing rat kidney, Kidney Int, 52, 309, 10.1038/ki.1997.336 Evian-Brion, 1994, Epidermal growth factor receptor and human fetoplacental development, J Pediatr Endocrinol, 7, 295 Lee, 1995, Requirement for neuregulin receptor erbB2 in neural and cardiac development, Nature, 378, 394, 10.1038/378394a0 Trussell, 2004, Contraceptive failure in the United States, Contraception, 74, 89, 10.1016/j.contraception.2004.03.009 Park, 2004, EGF-like growth factors as mediators of LH action in the ovulatory follicle, Science, 303, 682, 10.1126/science.1092463 Ashkenazi, 2005, Epidermal growth factor family members: endogenous mediators of the ovulatory response, Endocrinology, 146, 77, 10.1210/en.2004-0588 Conti, 2006, Role of the epidermal growth factor network in ovarian follicles, Mol Endocrinol, 20, 715, 10.1210/me.2005-0185 Ni, 2004, Application of a gene vaccine targeting HER-2/neu in immunocontraception, DNA Cell Biol, 23, 807, 10.1089/dna.2004.23.807