Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer
Tài liệu tham khảo
Bishop, 1991, Molecular themes in oncogenesis, Cell, 64, 235, 10.1016/0092-8674(91)90636-D
Bromberg, 1999, Stat3 as an oncogene, Cell, 98, 295, 10.1016/S0092-8674(00)81959-5
Karin, 2006, Nuclear factor-kappaB in cancer development and progression, Nature, 441, 431, 10.1038/nature04870
Karin, 2006, NF-kB and cancer: mechanisms and targets, Mol Carcinog, 45, 355, 10.1002/mc.20217
Yu, 2007, Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment, Nat Rev Immunol, 7, 41, 10.1038/nri1995
Karin, 2002, NF-kB in cancer: from innocent bystander to major culprit, Nat Rev Cancer, 2, 301, 10.1038/nrc780
Karin, 2002, NF-kB at the crossroads of life and death, Nat Immunol, 3, 221, 10.1038/ni0302-221
Haura, 2005, Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer, Nat Clin Pract Oncol, 2, 315, 10.1038/ncponc0195
Karin, 2006, Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer, Cell, 124, 823, 10.1016/j.cell.2006.02.016
Darnell, 1994, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science, 264, 1415, 10.1126/science.8197455
Greten, 2005, NF-kB: linking inflammation and immunity to cancer development and progression, Nat Rev Immunol, 5, 749, 10.1038/nri1703
Balkwill, 2001, Inflammation and cancer: back to Virchow?, Lancet, 357, 539, 10.1016/S0140-6736(00)04046-0
Coussens, 2002, Inflammation and cancer, Nature, 420, 860, 10.1038/nature01322
Ghosh, 2002, Missing pieces in the NF-kB puzzle, Cell, 109, S81, 10.1016/S0092-8674(02)00703-1
Gilmore, 2003, The Re1/NF-kappa B/I kappa B signal transduction pathway and cancer, Cancer Treat Res, 115, 241, 10.1007/0-306-48158-8_10
Vallabhapurapu, 2009, Regulation and function of NF-kappaB transcription factors in the immune system, Annu Rev Immunol, 27, 693, 10.1146/annurev.immunol.021908.132641
Bezbradica, 2009, Integration of cytokine and heterologous receptor signaling pathways, Nat Immunol, 10, 333, 10.1038/ni.1713
Dinarello, 1994, The interleukin-1 family: 10 years of discovery, FASEB J., 8, 1314, 10.1096/fasebj.8.15.8001745
Karin, 2009, TNFR signaling: ubiquitin-conjugated TRAFfic signals control stop-and-go for MAPK signaling complexes, Immunol Rev, 228, 225, 10.1111/j.1600-065X.2008.00755.x
Kruglov, 2008, Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade: mouse models, Cytokine Growth Factor Rev, 19, 231, 10.1016/j.cytogfr.2008.04.010
Karin, 2008, The IkappaB kinase—a bridge between inflammation and cancer, Cell Res, 18, 334, 10.1038/cr.2008.30
DiDonato, 1997, A cytokine-responsive IkB kinase that activates the transcription factor NF-kB, Nature, 388, 548, 10.1038/41493
Chen, 2001, Duration of nuclear NF-kappaB action regulated by reversible acetylation, Science, 293, 1653, 10.1126/science.1062374
Beg, 1996, An essential role for NF-kB in preventing TNF-a induced cell death, Science, 274, 782, 10.1126/science.274.5288.782
Liu, 1996, Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis, while NF-kB activation prevents cell death, Cell, 87, 565, 10.1016/S0092-8674(00)81375-6
Van Antwerp, 1996, Suppression of TNFa-induced apoptosis by NF-kB, Science, 274, 787, 10.1126/science.274.5288.787
Wang, 1996, TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kB, Science, 274, 784, 10.1126/science.274.5288.784
Joyce, 2001, NF-kappaB and cell-cycle regulation: the cyclin connection, Cytokine Growth Factor Rev, 12, 73, 10.1016/S1359-6101(00)00018-6
Mantovani, 2008, Cancer-related inflammation, Nature, 454, 436, 10.1038/nature07205
Huang, 2001, Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha, Mol Cell Biol, 21, 4737, 10.1128/MCB.21.14.4737-4747.2001
Luo, 2004, Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression, Cancer Cell, 6, 297, 10.1016/j.ccr.2004.08.012
Yu, 2004, The STATs of cancer--new molecular targets come of age, Nat Rev Cancer, 4, 97, 10.1038/nrc1275
Yoshimura, 2007, SOCS proteins, cytokine signalling and immune regulation, Nat Rev Immunol, 7, 454, 10.1038/nri2093
Braunstein, 2003, STATs dimerize in the absence of phosphorylation, J Biol Chem, 278, 34133, 10.1074/jbc.M304531200
Yang, 2007, Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB, Genes Dev, 21, 1396, 10.1101/gad.1553707
Hirano, 2000, Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors, Oncogene, 19, 2548, 10.1038/sj.onc.1203551
Wen, 1995, Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation, Cell, 82, 241, 10.1016/0092-8674(95)90311-9
Yuan, 2005, Stat3 dimerization regulated by reversible acetylation of a single lysine residue, Science, 307, 269, 10.1126/science.1105166
Lee, 2009, Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors, Cancer Cell, 15, 283, 10.1016/j.ccr.2009.02.015
Takeda, 1997, Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality, Proc Natl Acad Sci USA, 94, 3801, 10.1073/pnas.94.8.3801
Grivennikov, 2008, Autocrine IL-6 signaling: a key event in tumorigenesis?, Cancer Cell, 13, 7, 10.1016/j.ccr.2007.12.020
Kubo, 2003, Suppressors of cytokine signaling and immunity, Nat Immunol, 4, 1169, 10.1038/ni1012
Sansone, 2007, IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland, J Clin Invest, 117, 3988, 10.1172/JCI32533
Yin, 2006, Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions, Mol Cancer, 5, 15, 10.1186/1476-4598-5-15
Grivennikov, 2009, IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer, Cancer Cell, 15, 103, 10.1016/j.ccr.2009.01.001
Wang, 2009, IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway, J Exp Med, 10.1084/jem.20090207
Bollrath, 2009, gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis, Cancer Cell, 15, 91, 10.1016/j.ccr.2009.01.002
Jenkins, 2005, The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis, Blood, 105, 3512, 10.1182/blood-2004-09-3751
Judd, 2004, Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130, Gastroenterology, 126, 196, 10.1053/j.gastro.2003.10.066
Chan, 2004, Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis, J Clin Invest, 114, 720, 10.1172/JCI200421032
Kataoka, 2008, Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis, Carcinogenesis, 29, 1108, 10.1093/carcin/bgn061
Kortylewski, 2009, Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment, Cancer Cell, 15, 114, 10.1016/j.ccr.2008.12.018
Fu, 2006, STAT3 in immune responses and inflammatory bowel diseases, Cell Res, 16, 214, 10.1038/sj.cr.7310029
Darnell, 2002, Transcription factors as targets for cancer therapy, Nat Rev Cancer, 2, 740, 10.1038/nrc906
Ghoreschi, 2009, Janus kinases in immune cell signaling, Immunol Rev, 228, 273, 10.1111/j.1600-065X.2008.00754.x
Yang, 2005, Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation, Cancer Res, 65, 939, 10.1158/0008-5472.939.65.3
Dauer, 2005, Stat3 regulates genes common to both wound healing and cancer, Oncogene, 24, 3397, 10.1038/sj.onc.1208469
Yu, 2002, Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB, Biochem J, 367, 97, 10.1042/bj20020588
Yoshida, 2004, Interleukin 1 activates STAT3/nuclear factor-kappaB crosstalk via a unique TRAF6- and p65-dependent mechanism, J Biol Chem, 279, 1768, 10.1074/jbc.M311498200
Battle, 2002, The role of STATs in apoptosis, Curr Mol Med, 2, 381, 10.2174/1566524023362456
Wu, 2009, Nuclear protein IkappaB-zeta inhibits the activity of STAT3, Biochem Biophys Res Commun, 387, 348, 10.1016/j.bbrc.2009.07.023
Totzke, 2006, A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding, J Biol Chem, 281, 12645, 10.1074/jbc.M511956200
Levy, 2002, Stats: transcriptional control and biological impact, Nat Rev Mol Cell Biol, 3, 651, 10.1038/nrm909
Chen, 2002, Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB, EMBO J, 21, 6539, 10.1093/emboj/cdf660
Hoffmann, 2003, Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities, EMBO J, 22, 5530, 10.1093/emboj/cdg534
Hagihara, 2005, Essential role of STAT3 in cytokine-driven NF-kappaB-mediated serum amyloid A gene expression, Genes Cells, 10, 1051, 10.1111/j.1365-2443.2005.00900.x
Yoshimura, 2003, Negative regulation of cytokine signaling influences inflammation, Curr Opin Immunol, 15, 704, 10.1016/j.coi.2003.09.004
Zhang, 2008, Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity, Cell, 135, 61, 10.1016/j.cell.2008.07.043
Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9
Chang, 2006, The E3 ubiquitin ligase itch couples JNK activation to TNFa-induced cell death by inducing c-FLIP(L) turnover, Cell, 124, 601, 10.1016/j.cell.2006.01.021
Rebouissou, 2009, Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours, Nature, 457, 200, 10.1038/nature07475
Niu, 2005, Role of Stat3 in regulating p53 expression and function, Mol Cell Biol, 25, 7432, 10.1128/MCB.25.17.7432-7440.2005
Egan, 2004, IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium, Proc Natl Acad Sci USA, 101, 2452, 10.1073/pnas.0306734101
Tergaonkar, 2002, p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy, Cancer Cell, 1, 493, 10.1016/S1535-6108(02)00068-5
Naugler, 2008, NF-kappaB and cancer-identifying targets and mechanisms, Curr Opin Genet Dev, 18, 19, 10.1016/j.gde.2008.01.020
Cao, 2001, IKKa provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development, Cell, 107, 763, 10.1016/S0092-8674(01)00599-2
Tebbutt, 2002, Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice, Nat Med, 8, 1089, 10.1038/nm763
Pickert, 2009, STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing, J Exp Med, 206, 1465, 10.1084/jem.20082683
Kujawski, 2008, Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice, J Clin Invest, 118, 3367, 10.1172/JCI35213
Kim, 2007, Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis, Mol Carcinog, 46, 725, 10.1002/mc.20342
Niu, 2002, Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis, Oncogene, 21, 2000, 10.1038/sj.onc.1205260
Rius, 2008, NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha, Nature, 453, 807, 10.1038/nature06905
Bonecchi, 2009, Chemokines and chemokine receptors: an overview, Front Biosci, 14, 540, 10.2741/3261
Cheng, 2008, Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein, J Exp Med, 205, 2235, 10.1084/jem.20080132
Mailloux, 2009, NK-dependent increases in CCL22 secretion selectively recruits regulatory T cells to the tumor microenvironment, J Immunol, 182, 2753, 10.4049/jimmunol.0801124
Lin, 2007, A cytokine-mediated link between innate immunity, inflammation, and cancer, J Clin Invest, 117, 1175, 10.1172/JCI31537
Langowski, 2007, Swords into plowshares: IL-23 repurposes tumor immune surveillance, Trends Immunol, 28, 207, 10.1016/j.it.2007.03.006
Popivanova, 2008, Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis, J Clin Invest, 118, 560
Berg, 1996, Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses, J Clin Invest, 98, 1010, 10.1172/JCI118861
Dunn, 2004, The three Es of cancer immunoediting, Annu Rev Immunol, 22, 329, 10.1146/annurev.immunol.22.012703.104803
Swann, 2008, Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis, Proc Natl Acad Sci USA, 105, 652, 10.1073/pnas.0708594105
Hanada, 2006, IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice, J Exp Med, 203, 1391, 10.1084/jem.20060436
Dunn, 2004, The immunobiology of cancer immunosurveillance and immunoediting, Immunity, 21, 137, 10.1016/j.immuni.2004.07.017
Langowski, 2006, IL-23 promotes tumour incidence and growth, Nature, 442, 461, 10.1038/nature04808
Dercamp, 2005, Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses, Cancer Res, 65, 8479, 10.1158/0008-5472.CAN-05-1319
Kortylewski, 2005, Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity, Nat Med, 11, 1314, 10.1038/nm1325
Wang, 2004, Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells, Nat Med, 10, 48, 10.1038/nm976
Takeda, 1999, Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils, Immunity, 10, 39, 10.1016/S1074-7613(00)80005-9
Greten, 2004, IKKb links inflammation and tumorigenesis in a mouse model of colitis-associated cancer, Cell, 118, 285, 10.1016/j.cell.2004.07.013
Luedde, 2007, Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma, Cancer Cell, 11, 119, 10.1016/j.ccr.2006.12.016
Maeda, 2005, IKKb couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis, Cell, 121, 977, 10.1016/j.cell.2005.04.014
Naugler, 2007, Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production, Science, 317, 121, 10.1126/science.1140485
Kortylewski, 2005, Targeting STAT3 affects melanoma on multiple fronts, Cancer Metastasis Rev, 24, 315, 10.1007/s10555-005-1580-1
Becker, 2004, TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling, Immunity, 21, 491, 10.1016/j.immuni.2004.07.020
Balkwill, 2002, Tumor necrosis factor or tumor promoting factor?, Cytokine Growth Factor Rev, 13, 135, 10.1016/S1359-6101(01)00020-X
Izcue, 2008, Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis, Immunity, 28, 559, 10.1016/j.immuni.2008.02.019
Zhou, 2007, IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways, Nat Immunol, 8, 967, 10.1038/ni1488
Stewart, 2009, Reinforcing suppression using regulators: a new link between STAT3, IL-23, and Tregs in tumor immunosuppression, Cancer Cell, 15, 81, 10.1016/j.ccr.2009.01.008
O'Shea, 2008, Cytokine signaling modules in inflammatory responses, Immunity, 28, 477, 10.1016/j.immuni.2008.03.002
Weigmann, 2008, The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis, J Exp Med, 205, 2099, 10.1084/jem.20072484
Rose-John, 2009, Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease, Curr Pharm Des, 15, 2095, 10.2174/138161209788489140
Greten, 2007, NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta, Cell, 130, 918, 10.1016/j.cell.2007.07.009