DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients

Autoimmunity Reviews - Tập 7 - Trang 376-383 - 2008
Ying Zhou1, Qianjin Lu1
1Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Hunan 410011, PR China

Tài liệu tham khảo

Richardson, 1992, Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus, Arthritis Rheum, 35, 647, 10.1002/art.1780350608 Kaplan, 2004, Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells, J Immunol, 172, 3652, 10.4049/jimmunol.172.6.3652 Oelke, 2004, Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors, Arthritis Rheum, 50, 1850, 10.1002/art.20255 Lu, 2007, Demethylation of CD40LG on the inactive X in T cells from women with lupus, J Immunol, 179, 6352, 10.4049/jimmunol.179.9.6352 Holliday, 2006, Epigenetics: a historical overview, Epigenetics, 1, 76, 10.4161/epi.1.2.2762 Weber, 2007, Genomic patterns of DNA methylation: targets and function of an epigenetic mark, Curr Opin Cell Biol, 19, 273, 10.1016/j.ceb.2007.04.011 Rodenhiser, 2006, Epigenetics and human disease: translating basic biology into clinical applications, CMAJ, 174, 341, 10.1503/cmaj.050774 Klose, 2006, Genomic DNA methylation: the mark and its mediators, Trends Biochem Sci, 31, 89, 10.1016/j.tibs.2005.12.008 Kass, 1997, How does DNA methylation repress transcription?, Trends Genet, 13, 444, 10.1016/S0168-9525(97)01268-7 Wilson, 2007, DNA hypomethylation and human diseases, Biochim Biophys Acta, 1775, 138 Richardson, 1986, Effect of an inhibitor of DNA methylation on T cells. II. 5-Azacytidine induces self-reactivity in antigen-specific T4+ cells, Hum Immunol, 17, 456, 10.1016/0198-8859(86)90304-6 Richardson, 1990, Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis, Arthritis Rheum, 33, 1665, 10.1002/art.1780331109 Corvetta, 1991, 5-Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmune rheumatic diseases, J Chromatogr, 566, 481, 10.1016/0378-4347(91)80265-E Cornachia, 1988, Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity, J Immunol, 140, 2197, 10.4049/jimmunol.140.7.2197 Richardson, 1994, Lymphocyte function-associated antigen 1 overexpression and T cell autoreactivity, Arthritis Rheum, 37, 1363, 10.1002/art.1780370915 Yung, 1997, Mechanisms of drug-induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo, Arthritis Rheum, 40, 1436, 10.1002/art.1780400811 Quddus, 1993, Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice, J Clin Invest, 92, 38, 10.1172/JCI116576 Yung, 1995, Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo, J Immunol, 154, 3025, 10.4049/jimmunol.154.6.3025 Richardson, 2003, DNA methylation and autoimmune disease, Clin Immunol, 109, 72, 10.1016/S1521-6616(03)00206-7 Hogg, 2003, T-cell integrins—more than just sticking points, J Cell Sci, 116, 4695, 10.1242/jcs.00876 Yung, 1996, Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice, J Clin Invest, 97, 2866, 10.1172/JCI118743 Lu, 2002, Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus, Arthritis Rheum, 46, 1282, 10.1002/art.10234 van den Broek, 2000, The role of perforin in infections and tumour surveillance, Exp Physiol, 85, 681, 10.1017/S0958067000020972 Kobata, 1995, CD27–CD70 interactions regulate B-cell activation by T cells, Proc Natl Acad Sci USA, 92, 11249, 10.1073/pnas.92.24.11249 Sawalha, 2007, Defective DNA methylation and CD70 overexpression in CD4+ T cells in MRL/lpr lupus-prone mice, Eur J Immunol, 37, 1407, 10.1002/eji.200636872 Lu, 2005, Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs, J Immunol, 174, 6212, 10.4049/jimmunol.174.10.6212 Heard, 2006, Dosage compensation in mammals: fine-tuning the expression of the X chromosome, Genes Dev, 20, 1848, 10.1101/gad.1422906 Ross, 2005, The DNA sequence of the human X chromosome, Nature, 434, 325, 10.1038/nature03440 Deng, 2001, Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients, Arthritis Rheum, 44, 397, 10.1002/1529-0131(200102)44:2<397::AID-ANR59>3.0.CO;2-N Balada, 2007, DNA methylation and systemic lupus erythematosus, Ann N Y Acad Sci, 1108, 127, 10.1196/annals.1422.015 Januchowski, 2008, Prevalence of ZAP-70, LAT, SLP-76, and DNA methyltransferase 1 expression in CD4(+) T cells of patients with systemic lupus erythematosus, Clin Rheumatol, 27, 21, 10.1007/s10067-007-0644-8 Yang, 1997, Effect of mitogenic stimulation and DNA methylation on human T cell DNA methyltransferase expression and activity, J Immunol, 159, 1303, 10.4049/jimmunol.159.3.1303 Scheinbart, 1991, Procainamide inhibits DNA methyltransferase in a human T cell line, J Rheumatol, 18, 530 Deng, 2003, Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling, Arthritis Rheum, 48, 746, 10.1002/art.10833 Klinman, 1986, Oncogene expression in autoimmune and normal peripheral blood mononuclear cells, J Exp Med, 163, 1292, 10.1084/jem.163.5.1292 Balada, 2007, Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients, J Leukoc Biol, 81, 1609, 10.1189/jlb.0107064 Richardson, 1990, CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation, Clin Immunol Immunopathol, 55, 368, 10.1016/0090-1229(90)90125-A Kaplan, 2000, TRAIL (Apo2 ligand) and TWEAK (Apo3 ligand) mediate CD4+ T cell killing of antigen-presenting macrophages, J Immunol, 164, 2897, 10.4049/jimmunol.164.6.2897 Lu, 2003, DNA methylation and chromatin structure regulate T cell perforin gene expression, J Immunol, 170, 5124, 10.4049/jimmunol.170.10.5124 Yung, 2001, Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies, Lupus, 10, 539, 10.1191/096120301701549660