DNA methylation and exposure to violence among African American young adult males

Alizadeh, 2018, Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury, J. Neuroinflammation, 15, 53, 10.1186/s12974-018-1093-9

Allport, 2019, Influence of parent stressors on adolescent obesity in African American youth, J Obes, 2019, 1316765

Aryee, 2014, Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays, Bioinformatics, 30, 1363, 10.1093/bioinformatics/btu049

Assari, 2019, Obesity and polypharmacy among African American older adults: gender as the moderator and multimorbidity as the mediator, Int. J. Environ. Res. Publ. Health, 16, 10.3390/ijerph16122181

Baldwin, 2018, Childhood victimization and inflammation in young adulthood: a genetically sensitive cohort study, Brain Behav. Immun., 67, 211, 10.1016/j.bbi.2017.08.025

Bali, 2011, Methylation, memory and addiction, Epigenetics, 6, 671, 10.4161/epi.6.6.15905

Barcelona de Mendoza, 2018, Perceived racial discrimination and DNA methylation among African American women in the InterGEN study, Biol. Res. Nurs., 20, 145, 10.1177/1099800417748759

Barengolts, 2019, Predictors of obesity among gut microbiota biomarkers in African American men with and without diabetes, Microorganisms, 7, 10.3390/microorganisms7090320

Barker, 2018, Annual Research Review: DNA methylation as a mediator in the association between risk exposure and child and adolescent psychopathology, JCPP (J. Child Psychol. Psychiatry), 59, 303, 10.1111/jcpp.12782

Boulet, 2019, The orphan nuclear receptor NR4A3 controls the differentiation of monocyte-derived dendritic cells following microbial stimulation, Proc. Natl. Acad. Sci. U. S. A., 116, 15150, 10.1073/pnas.1821296116

Breitenkamp, 2014, Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function, PLoS One, 9, 10.1371/journal.pone.0095579

Buchser, 2010, Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology, Mol. Syst. Biol., 6, 391, 10.1038/msb.2010.52

Bunin, 2015, Protein tyrosine phosphatase PTPRS is an inhibitory receptor on human and murine plasmacytoid dendritic cells, Immunity, 43, 277, 10.1016/j.immuni.2015.07.009

Caillier, 2008, Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis, J. Immunol., 181, 5473, 10.4049/jimmunol.181.8.5473

Calle-Fabregat, 2020, Understanding the relevance of DNA methylation changes in immune differentiation and disease, Genes, 11, 10.3390/genes11010110

Cao, 2019, HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2, P Natl Acad Sci USA, 116, 5487, 10.1073/pnas.1815365116

Cecil, 2016, Epigenetic signatures of childhood abuse and neglect: implications for psychiatric vulnerability, J. Psychiatr. Res., 83, 184, 10.1016/j.jpsychires.2016.09.010

Christopher, 2017, Neuroepigenetic mechanisms in disease, Epigenet. Chromatin, 10, 47, 10.1186/s13072-017-0150-4

Durdiakova, 2014, STX1A and Asperger syndrome: a replication study, Mol. Autism., 5, 14, 10.1186/2040-2392-5-14

Ebrahimi, 2020, Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation - can blood be used as a surrogate for bone?, Epigenetics, 1

El Hajj, 2017, Epigenetic dysregulation of protocadherins in human disease, Semin. Cell Dev. Biol., 69, 172, 10.1016/j.semcdb.2017.07.007

Eltokhi, 2018, Distinct phenotypes of Shank2 mouse models reflect neuropsychiatric spectrum disorders of human patients with SHANK2 variants, Front. Mol. Neurosci., 11, 240, 10.3389/fnmol.2018.00240

Faucher, 2019, Exploration of the vaginal and gut microbiome in African American women by body mass index, class of obesity, and gestational weight gain: a pilot study, Am. J. Perinatol.

Finkelhor, 2010, Trends in childhood violence and abuse exposure: evidence from 2 national surveys, Arch. Pediatr. Adolesc. Med., 164, 238, 10.1001/archpediatrics.2009.283

Finkelhor, 2015, Prevalence of childhood exposure to violence, crime, and abuse: results from the national survey of children’s exposure to violence, JAMA Pediatr, 169, 746, 10.1001/jamapediatrics.2015.0676

Francisco, 2015, TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis, J. Neuroinflammation, 12, 125, 10.1186/s12974-015-0345-1

Giurgescu, 2019, Neighborhood environment and DNA methylation: implications for cardiovascular disease risk, J. Urban Health, 96, 23

Go, 2014, Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association, Circulation, 129, 399, 10.1161/01.cir.0000442015.53336.12

Goldmann, 2011, Pervasive exposure to violence and posttraumatic stress disorder in a predominantly African American urban community: the detroit neighborhood health study, J. Trauma Stress, 24, 747, 10.1002/jts.20705

Goode, 2017, African Americans in standard behavioral treatment for obesity, 2001-2015: what have we learned?, West. J. Nurs. Res., 39, 1045, 10.1177/0193945917692115

Griggs, 2019, Violence exposure, conflict, and health outcomes in inner-city African American adolescents, Nurs. Forum, 54, 513, 10.1111/nuf.12365

Hadar, 2016, RGS2 expression predicts amyloid-beta sensitivity, MCI and Alzheimer’s disease: genome-wide transcriptomic profiling and bioinformatics data mining, Transl. Psychiatry, 6, e909, 10.1038/tp.2016.179

Huang, 2009, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nat. Protoc., 4, 44, 10.1038/nprot.2008.211

Iborra, 2011, H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity, Blood, 117, 5102, 10.1182/blood-2010-10-315770

Intarasunanont, 2012, Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in a human lymphoblast cell line, Environ. Health, 11, 31, 10.1186/1476-069X-11-31

Jacobs, 2014, Perceived discrimination is associated with reduced breast and cervical cancer screening: the Study of Women’s Health across the Nation (SWAN), J Womens Health (Larchmt), 23, 138, 10.1089/jwh.2013.4328

Jovanovic, 2017, Exposure to violence accelerates epigenetic aging in children, Sci. Rep., 7, 8962, 10.1038/s41598-017-09235-9

Kerepesi, 2006, Complement component C3 is required for protective innate and adaptive immunity to larval strongyloides stercoralis in mice, J. Immunol., 176, 4315, 10.4049/jimmunol.176.7.4315

Lahtinen, 2019, A distinctive DNA methylation pattern in insufficient sleep, Sci. Rep., 9, 1193, 10.1038/s41598-018-38009-0

Lai Wing Sun, 2011, Netrins: versatile extracellular cues with diverse functions, Development, 138, 2153, 10.1242/dev.044529

Lee, 2012, Dab2ip regulates neuronal migration and neurite outgrowth in the developing neocortex, PLoS One, 7, 10.1371/journal.pone.0046592

Lee, 2016, Cytoplasmic Rbfox1 regulates the expression of synaptic and autism-related genes, Neuron, 89, 113, 10.1016/j.neuron.2015.11.025

Legendre, 2001, The glycinergic inhibitory synapse, Cell. Mol. Life Sci., 58, 760, 10.1007/PL00000899

Li, 2005, Foxn4 acts synergistically with Mash1 to specify subtype identity of V2 interneurons in the spinal cord, P Natl Acad Sci USA, 102, 10688, 10.1073/pnas.0504799102

Li, 2019, Association of obesity with DNA methylation age acceleration in African American mothers from the InterGEN study, Int. J. Mol. Sci., 20, 10.3390/ijms20174273

Lipstein, 2017, Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder, J. Clin. Invest., 127, 1005, 10.1172/JCI90259

Little, 2001, Memory of childhood sexual abuse among clinicians: characteristics, outcomes, and current therapy attitudes, Sex Abuse, 13, 233, 10.1177/107906320101300402

Lockwood, 2015, The role of epigenetics in depression and suicide: a platform for gene-environment interactions, Psychiatr. Res., 228, 235, 10.1016/j.psychres.2015.05.071

Luo, 2008, Nr4a2 is essential for the differentiation of dopaminergic neurons during zebrafish embryogenesis, Mol. Cell. Neurosci., 39, 202, 10.1016/j.mcn.2008.06.010

Ly, 2008, DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1, Cell, 133, 1241, 10.1016/j.cell.2008.05.030

Lyst, 2013, Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor, Nat. Neurosci., 16, 898, 10.1038/nn.3434

Mansell, 2019, Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array, BMC Genom., 20, 366, 10.1186/s12864-019-5761-7

McDade, 2019, Genome-wide analysis of DNA methylation in relation to socioeconomic status during development and early adulthood, Am. J. Phys. Anthropol., 169, 3, 10.1002/ajpa.23800

McGee, 2001, Urban stress and mental health among African-American youth: assessing the link between exposure to violence, problem behavior, and coping strategies, J. Cult. Divers., 8, 94

McKay, 2011, Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice, Mol. Nutr. Food Res., 55, 1026, 10.1002/mnfr.201100008

Mei, 2008, Neuregulin 1 in neural development, synaptic plasticity and schizophrenia, Nat. Rev. Neurosci., 9, 437, 10.1038/nrn2392

Mitchell, 2010, How does violence exposure affect the psychological health and parenting of young African-American mothers?, Soc. Sci. Med., 70, 526, 10.1016/j.socscimed.2009.10.048

Moffitt, 2013, Childhood exposure to violence and lifelong health: clinical intervention science and stress-biology research join forces, Dev. Psychopathol., 25, 1619, 10.1017/S0954579413000801

Murata, 2019, Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies, Neuropsychopharmacol. Rep., 39, 301, 10.1002/npr2.12075

Nagaoka, 2017, The orphan nuclear receptor NR4A3 is involved in the function of dendritic cells, J. Immunol., 199, 2958, 10.4049/jimmunol.1601911

Nagy, 2020, Association between asthma, obesity, and health behaviors in African American youth, J. Asthma, 57, 410, 10.1080/02770903.2019.1571083

Nakagawa, 2003, Role of mannan-binding protein, MBP, in innate immunity, Anticancer Res., 23, 4467

Nakamura, 2008, Genetic and expression analyses reveal elevated expression of syntaxin 1A ( STX1A) in high functioning autism, Int. J. Neuropsychopharmacol., 11, 1073, 10.1017/S1461145708009036

Naumova, 2012, Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents, Dev. Psychopathol., 24, 143, 10.1017/S0954579411000605

Odagiu, 2016, NR4A3 controls CD8+T cell metabolism and differentiation, J. Immunol., 196, 10.4049/jimmunol.196.Supp.57.8

Ogawa, 2018, Elavl3 is essential for the maintenance of Purkinje neuron axons, Sci. Rep., 8, 2722, 10.1038/s41598-018-21130-5

Ohtsuka, 2013, GABAergic neurons regulate lateral ventricular development via transcription factor Pax5, Genesis, 51, 234, 10.1002/dvg.22370

Olofsson, 2012, Long-term health consequences of violence exposure in adolescence: a 26-year prospective study, BMC Publ. Health, 12, 411, 10.1186/1471-2458-12-411

Ozato, 2008, TRIM family proteins and their emerging roles in innate immunity, Nat. Rev. Immunol., 8, 849, 10.1038/nri2413

Paranjape, 2010, Family violence exposure and health outcomes among older African American women: do spirituality and social support play protective roles?, J Womens Health (Larchmt), 19, 1899, 10.1089/jwh.2009.1845

Paranjape, 2009, Lifetime exposure to family violence: implications for the health status of older African American women, J Womens Health (Larchmt), 18, 171, 10.1089/jwh.2008.0850

Raveney, 2013, Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling, PLoS One, 8, 10.1371/journal.pone.0056595

Ritchie, 2015, Limma powers differential expression analyses for RNA-sequencing and microarray studies, Nucleic Acids Res., 43, e47, 10.1093/nar/gkv007

Saadatmand, 2017, Gender differences and the impact of exposure to violence on depressive symptoms and sleep habits among young African American adults, J. Family Strengths, 17

Saadatmand, 2019, Violence exposure, drug use and HIV/AIDS risk taking behaviors: the role of gender, J. Natl. Med. Assoc.

Safe, 2016, Nuclear receptor 4A (NR4A) family - orphans no more, J. Steroid Biochem. Mol. Biol., 157, 48, 10.1016/j.jsbmb.2015.04.016

Scheckel, 2016, Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain, Elife, 5, 10.7554/eLife.10421

Sen, 2015, Early life lead exposure causes gender-specific changes in the DNA methylation profile of DNA extracted from dried blood spots, Epigenomics, 7, 379, 10.2217/epi.15.2

Sen, 2015, Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren, Sci. Rep., 5, 14466, 10.1038/srep14466

Serpeloni, 2019, Does prenatal stress shape postnatal resilience? - an epigenome-wide study on violence and mental health in humans, Front. Genet., 10, 269, 10.3389/fgene.2019.00269

Serpeloni, 2020, Experiencing community and domestic violence is associated with epigenetic changes in DNA methylation of BDNF and CLPX in adolescents, Psychophysiology, 57, 10.1111/psyp.13382

Solomon, 2018, Comparison of DNA methylation measured by Illumina 450K and EPIC BeadChips in blood of newborns and 14-year-old children, Epigenetics, 13, 655, 10.1080/15592294.2018.1497386

Song, 2016, Combined analysis of DNA methylome and transcriptome reveal novel candidate genes with susceptibility to bovine Staphylococcus aureus subclinical mastitis, Sci. Rep., 6, 29390, 10.1038/srep29390

Stith, 2002, The anger management scale: development and preliminary psychometric properties, Violence Vict., 17, 383, 10.1891/vivi.17.4.383.33683

Tang, 2007, Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress, Oncogene, 26, 7302, 10.1038/sj.onc.1210542

Taylor, 2019, Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle, Proc. Natl. Acad. Sci. U. S. A., 116, 10883, 10.1073/pnas.1814263116

Triche, 2013, Low-level processing of Illumina Infinium DNA methylation BeadArrays, Nucleic Acids Res., 41, e90, 10.1093/nar/gkt090

Uddin, 2013, Sex differences in DNA methylation may contribute to risk of PTSD and depression: a review of existing evidence, Depress. Anxiety, 30, 1151, 10.1002/da.22167

Uddin, 2018, Epigenetic meta-analysis across three civilian cohorts identifies NRG1 and HGS as blood-based biomarkers for post-traumatic stress disorder, Epigenomics, 10, 1585, 10.2217/epi-2018-0049

Umeda, 2019, RasGRF1 mediates brain-derived neurotrophic factor-induced axonal growth in primary cultured cortical neurons, Biochem. Biophys. Rep., 17, 56

Vick, 2017, Epigenetics and health disparities, Curr. Epidemiol. Rep., 4, 31, 10.1007/s40471-017-0096-x

Welberg, 2001, Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: possible implications for behaviour, Neuroscience, 104, 71, 10.1016/S0306-4522(01)00065-3

Wen, 2019, NDRG4 protects against cerebral ischemia injury by inhibiting p53-mediated apoptosis, Brain Res. Bull., 146, 104, 10.1016/j.brainresbull.2018.12.010

Woodson, 2010, Violence exposure and health related risk among African American adolescent female detainees: a strategy for reducing recidivism, J. Offender Rehabil., 49, 571, 10.1080/10509674.2010.519669

Wu, 2017, Nuclear accumulation of histone deacetylase 4 (HDAC4) exerts neurotoxicity in models of Parkinson’s disease, Mol. Neurobiol., 54, 6970, 10.1007/s12035-016-0199-2

Yang, 2019, Oral microbiome and obesity in a large study of low-income and African-American populations, J. Oral Microbiol., 11, 1650597, 10.1080/20002297.2019.1650597

Zhang, 2017, Reversing SKI-SMAD4-mediated suppression is essential for T(H)17 cell differentiation, Nature, 551, 105, 10.1038/nature24283

Zhang, 2018, Immune cell production of interleukin 17 induces stem cell features of pancreatic intraepithelial neoplasia cells, Gastroenterology, 155, 210, 10.1053/j.gastro.2018.03.041

Zhong, 2003, L-Glycine: A novel antiinflammatory, immunomodulatory, and cytoprotective agent, Curr. Opin. Clin. Nutr. Metab. Care, 6, 229, 10.1097/00075197-200303000-00013