Cystatin C as a marker of GFR—history, indications, and future research

Clinical Biochemistry - Tập 38 Số 1 - Trang 1-8 - 2005
Guido Filler1, Arend Bökenkamp2, Walter Hofmann3, Thierry Le Bricon4, Cecília Martínez-Brú5, Anders Grubb6
1Department of Pediatrics, Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada
2Department of Pediatrics, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
3Department of Clinical Chemistry, München, Germany
4Laboratoire de Biochimie A, Hôpital St-Louis, Vellefaux, 75010 Paris, France
5Servei de Bioquimica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
6Department of Clinical Chemistry, University Hospital, S - 22185 Lund, Sweden

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Grubb, 1982, Human γ-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis, Proc. Natl. Acad. Sci. U. S. A., 79, 3024, 10.1073/pnas.79.9.3024

Barrett, 1986, Cysteine proteinase inhibitors of the cystatin super-family, 515

Barrett, 1984, The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors, Biochem. Biophys. Res. Commun., 120, 631, 10.1016/0006-291X(84)91302-0

Brzin, 1984, Human cystatin, a new protein inhibitor of cysteine proteinases, Biochem. Biophys. Res. Commun., 118, 103, 10.1016/0006-291X(84)91073-8

Schwabe, 1984, Cystatin Amino acid sequence and possible secondary structure, Biochem. J., 217, 813, 10.1042/bj2170813

Turk, 1983, Protein inhibitors of cysteine proteinases: III. Amino-acid sequence of cystatin from chicken egg white, Hoppe-Seyler's Z. Physiol. Chem., 364, 1487, 10.1515/bchm2.1983.364.2.1487

Abrahamson, 1990, Structure and expression of the human cystatin C gene, Biochem. J., 268, 287, 10.1042/bj2680287

Lignelid, 1992, Cystatin C in the human pancreas and gut: an immunohistochemical study of normal and neoplastic tissues, Virchows Arch. A Pathol. Anat. Histopathol., 421, 491, 10.1007/BF01606878

Lignelid, 1997, Cystatin C and transthyretin expression in normal and neoplastic tissues of the human brain and pituitary, Acta Neuropathol. (Berl.), 93, 494, 10.1007/s004010050644

Jacobsson, 1995, Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas, Histopathology, 26, 559, 10.1111/j.1365-2559.1995.tb00275.x

Ni, 1998, Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor, J. Biol. Chem., 273, 24797, 10.1074/jbc.273.38.24797

Bjarnadottir, 1995, Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells, Scand. J. Clin. Lab. Invest., 55, 617, 10.3109/00365519509110261

Chapman, 1990, Identification of cystatin C, a cysteine proteinase inhibitor, as a major secretory product of human alveolar macrophages in vitro, Am. Rev. Respir. Dis., 141, 698, 10.1164/ajrccm/141.3.698

Abrahamson, 1987, Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C, FEBS Lett., 216, 229, 10.1016/0014-5793(87)80695-6

Grubb, 2000, Cystatin C—Properties and use as diagnostic marker, Adv. Clin. Chem., 35, 63, 10.1016/S0065-2423(01)35015-1

Dharnidharka, 2002, Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis, Am. J. Kidney Dis., 40, 221, 10.1053/ajkd.2002.34487

Grubb, 1993, Cystatin C, vol. 2.

Janowski, 2001, Human cystatin C, a protein with amyloidogenic properties, dimerizes through 3D domain swapping, Nat. Struct. Biol., 8, 316, 10.1038/86188

Bode, 1988, The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases, EMBO J., 7, 2593, 10.1002/j.1460-2075.1988.tb03109.x

Bjarnadóttir, 1995, Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells, Scand. J. Clin. Lab. Invest., 55, 617, 10.3109/00365519509110261

Risch, 2001, Effects of glucocorticoid immunosuppression on serum cystatin C concentrations in renal transplant patients, Clin. Chem., 47, 2055, 10.1093/clinchem/47.11.2055

Bökenkamp, 2002, Effect of corticosteroid therapy on serum cystatin C and beta2-microglobulin concentrations, Clin. Chem., 48, 1123, 10.1093/clinchem/48.7.1123

Fricker, 2003, Impact of thyroid dysfunction on serum cystatin C, Kidney Int., 63, 1944, 10.1046/j.1523-1755.2003.00925.x

Wiesli, 2003, Serum cystatin C is sensitive to small changes in thyroid function, Clin. Chim. Acta, 338, 87, 10.1016/j.cccn.2003.07.022

Jung, 1987, Low-molecular-mass proteins in serum and their relationship to the glomerular filtration rate, Nephron, 47, 160, 10.1159/000184483

Grubb, 1985, Serum concentration of cystatin C, factor D and b2-microglobulin as a measure of glomerular filtration rate, Acta Med. Scand., 218, 499, 10.1111/j.0954-6820.1985.tb08880.x

Tenstad, 1996, Renal handling of radiolabelled human cystatin C in the rat, Scand. J. Clin. Lab. Invest., 56, 409, 10.3109/00365519609088795

Simonsen, 1985, The blood serum concentration of cystatin C (gamma-trace) as a measure of the glomerular filtration rate, Scand. J. Clin. Lab. Invest., 45, 97, 10.3109/00365518509160980

Löfberg, 1979, Quantitation of g-trace in human biological fluids: indications for production in the central nervous system, Scand. J. Clin. Lab. Invest., 39, 619, 10.3109/00365517909108866

Kyhse-Andersen, 1994, Serum cystatin C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular filtration rate, Clin. Chem., 40, 1921, 10.1093/clinchem/40.10.1921

Newman, 1995, Serum cystatin C measured by automated immunoassay: a more sensitive marker of changes in GFR than serum creatinine, Kidney Int., 47, 312, 10.1038/ki.1995.40

Finney, 1997, Initial evaluation of cystatin C measurement by particle-enhanced immunonephelometry on the Behring nephelometer systems (BNA, BN II), Clin. Chem., 43, 1016, 10.1093/clinchem/43.6.1016

Erlandsen, 1999, Evaluation of the Dade Behring N Latex Cystatin C assay on the Dade Behring Nephelometer II System, Scand. J. Clin. Lab. Invest., 59, 1, 10.1080/00365519950185940

Mussap, 1998, Quantitative automated particle-enhanced immunonephelometric assay for the routinary measurement of human cystatin C, Clin. Chem. Lab. Med., 36, 859, 10.1515/CCLM.1998.151

Vinge, 1999, Relationship among serum cystatin C, serum creatinine, lean tissue mass and glomerular filtration rate in healthy adults, Scand. J. Clin. Lab. Invest., 59, 587, 10.1080/00365519950185076

Perrone, 1992, Serum creatinine as an index of renal function: new insights into old concepts, Clin. Chem., 38, 1933, 10.1093/clinchem/38.10.1933

Bunchman, 1990, Manifestations of renal allograft rejection in small children receiving adult kidneys, Pediatr. Nephrol., 4, 255, 10.1007/BF00857670

Filler, 1997, Are Cystatin C and b2-microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects?, Clin. Chem., 43, 1077, 10.1093/clinchem/43.6.1077

Bökenkamp, 1998, Reference values for cystatin C serum concentrations in children, Pediatr. Nephrol., 12, 125, 10.1007/s004670050419

Randers, 1999, Reference interval for serum cystatin C in children, Clin. Chem., 45, 1856, 10.1093/clinchem/45.10.1856

Schwartz, 1976, A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine, Pediatrics, 58, 259, 10.1542/peds.58.2.259

Counahan, 1976, Estimation of glomerular filtration rate from plasma creatinine concentration in children, Arch. Dis. Child, 51, 875, 10.1136/adc.51.11.875

Schwartz, 1987, The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents, Pediatr. Clin. North Am., 34, 571, 10.1016/S0031-3955(16)36251-4

Brion, 1989, Estimation of glomerular filtration rate in anorectic adolescents, Pediatr. Nephrol., 3, 16, 10.1007/BF00859618

Norlund, 1997, Reference intervals for the glomerular filtration rate and cell proliferation markers: serum cystatin C and serum b2-microglobulin/cystatin C-ratio, Scand. J. Clin. Lab. Invest., 57, 463, 10.3109/00365519709084595

Harmoinen, 2000, Reference intervals for cystatin C in pre- and full-term infants and children, Pediatr. Nephrol., 15, 105, 10.1007/s004670000421

Fischbach, 2002, Impact of age on reference values for serum concentration of cystatin C in children, Pediatr. Nephrol., 17, 104, 10.1007/s00467-001-0777-y

Bökenkamp, 1999, Pediatric reference values for cystatin C revisited, Pediatr. Nephrol., 13, 367

Galteau, 2001, Determination of serum cystatin C: biological variation and reference values, Clin. Chem. Lab. Med., 39, 850, 10.1515/CCLM.2001.141

Cataldi, 1999, Cystatin C in healthy women at term pregnancy and in their infant newborns: relationship between maternal and neonatal serum levels and reference values, Am. J. Perinatol., 16, 287, 10.1055/s-2007-993874

Bökenkamp, 2001, Fetal serum concentrations of cystatin C and beta2-microglobulin as predictors of postnatal kidney function, Am. J. Obstet. Gynecol., 185, 468, 10.1067/mob.2001.115283

Harmoinen, 2000, Reference intervals for cystatin C in pre- and full-term infants and children, Pediatr. Nephrol., 15, 105, 10.1007/s004670000421

Finney, 2000, Reference ranges for plasma cystatin C and creatinine measurements in premature infants, neonates, and older children, Arch. Dis. Child, 82, 71, 10.1136/adc.82.1.71

Stickle, 1998, Correlation of plasma concentrations of cystatin C and creatinine to inulin clearance in a pediatric population, Clin. Chem., 44, 1334, 10.1093/clinchem/44.6.1334

Bökenkamp, 1998, Cystatin C—A new marker of glomerular filtration rate in children independent of age and height, Pediatrics, 101, 875, 10.1542/peds.101.5.875

Filler, 1999, Diagnostic sensitivity of serum cystatin for impaired glomerular filtration rate, Pediatr. Nephrol., 13, 501, 10.1007/s004670050646

Ylinen, 1999, Cystatin C as a marker for glomerular filtration rate in pediatric patients, Pediatr. Nephrol., 13, 506, 10.1007/s004670050647

Kilpatrick, 2000, Does adjustment of GFR to extracellular fluid volume improve the clinical utility of cystatin C?, Arch. Dis. Child, 82, 499, 10.1136/adc.82.6.499

Bökenkamp, 1998, Reference values for cystatin C serum concentrations in children, Pediatr. Nephrol., 12, 125, 10.1007/s004670050419

Vinge, 1999, Relationships among serum cystatin C, serum creatinine, lean tissue mass and glomerular filtration rate in healthy adults, Scand. J. Clin. Lab. Invest., 59, 587, 10.1080/00365519950185076

Woitas, 2000, Correlation of serum concentrations of cystatin C and creatinine to inulin clearance in liver cirrhosis, Clin. Chem., 46, 712, 10.1093/clinchem/46.5.712

Pham-Huy, 2003, Measuring glomerular filtration rate with cystatin C and beta-trace protein in children with spina bifida, J. Urol., 169, 2312, 10.1097/01.ju.0000060205.23406.13

Thomassen, 2002, Serum cystatin C as a marker of the renal function in patients with spinal cord injury, Spinal Cord., 40, 524, 10.1038/sj.sc.3101320

Swedko, 2003, Serum creatinine is an inadequate screening test for renal failure in elderly patients, Arch. Intern. Med., 163, 356, 10.1001/archinte.163.3.356

Fliser, 2001, Serum cystatin C concentration as a marker of renal dysfunction in the elderly, Am. J. Kidney Dis., 37, 79, 10.1053/ajkd.2001.20591

Lamb, 2003, Kidney function in older people: pathology, assessment and management, Clin. Chim. Acta, 334, 25, 10.1016/S0009-8981(03)00246-8

Conrad, 1999, Renal and cardiovascular changes in normal pregnancy and preeclampsia, 263

Sturgiss, 1996, Renal reserve during human pregnancy, Am. J. Physiol. Renal. Fluid Electrolyte Physiol., 270, F16, 10.1152/ajprenal.1996.271.1.F16

Davison, 1980, 24-hour creatinine clearance during the third trimester of normal pregnancy, Br. J. Obstet. Gynaecol., 87, 106, 10.1111/j.1471-0528.1980.tb04501.x

Davison, 1981, Renal function in pregnancy, Contrib. Nephrol., 25, 4, 10.1159/000396004

Davison, 1980, Renal hemodynamics and tubular function normal human pregnancy, Kidney Int., 18, 152, 10.1038/ki.1980.124

Strevens, 2001, Grubb A: Serum cystatin C is a better marker for preeclampsia than serum creatinine or serum urate, Scand. J. Clin. Lab. Invest., 61, 575, 10.1080/003655101753218346

Strevens, 2002, Serum cystatin C for assessment of glomerular filtration rate in pregnant and non-pregnant women. Indications of altered filtration process in pregnancy, Scand. J. Clin. Lab. Invest., 62, 141, 10.1080/003655102753611771

Akbari, 2002, Abstract. Measurement of small molecular weight proteins as markers of GFR in pregnancy [SA-P0761], J. Am. Soc. Nephrol., 13, 420A

Roberts, 1996, Altered glomerular permselectivity to neutral dextrans and heteroporous membrane modeling in human pregnancy, Am. J. Physiol., 270, F338

Strevens, 2003, Serum cystatin C reflects glomerular endotheliosis in normal, hypertensive and pre-eclamptic pregnancies, BJOG, 110, 825, 10.1111/j.1471-0528.2003.02051.x

Plebani, 1998, Is serum cystatin C a sensitive marker of glomerular filtration rate (GFR)? A preliminary study on renal transplant patients, Ren. Fail., 20, 303, 10.3109/08860229809045115

Risch, 1999, Rapid and accurate assessment of glomerular filtration rate in patients with renal transplants using serum cystatin C, Nephrol. Dial. Transplant., 14, 1991, 10.1093/ndt/14.8.1991

Bökenkamp, 1999, Cystatin C and creatinine after successful kidney transplantation in children, Clin. Nephrol., 52, 371

Le Bricon, 1999, Changes in plasma cystatin C after renal transplantation and acute rejection in adults, Clin. Chem., 45, 2243, 10.1093/clinchem/45.12.2243

Le Bricon, 2000, Plasma cystatin C is superior to 24-h creatinine clearance and plasma creatinine for estimation of glomerular filtration rate 3 months after kidney transplantation, Clin. Chem., 46, 1206, 10.1093/clinchem/46.8.1206

Herget-Rosenthal, 2000, Cystatin C—An accurate marker of glomerular filtration rate after renal transplantation?, Transpl. Int., 13, 285, 10.1111/j.1432-2277.2000.tb01083.x

Hermida, 2002, Relationship between serum cystatin C and creatinine in kidney and liver transplant patients, Clin. Chim. Acta, 316, 165, 10.1016/S0009-8981(01)00728-8

Bland, 1986, Statistical methods for assessing agreement between two methods of clinical measurement, Lancet, 1, 307, 10.1016/S0140-6736(86)90837-8

Filler, 2003, Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula?, Pediatr. Nephrol., 18, 981, 10.1007/s00467-003-1271-5

Keevil, 1998, Biological variation of cystatin C: implications for the assessment of glomerular filtration rate, Clin. Chem., 44, 1535, 10.1093/clinchem/44.7.1535

Nilsson-Ehle, 1996, Biological variation of cystatin C concentration in serum, Scand. J. Clin. Lab. Invest., 56, 16

Schuck, 2003, Glomerular filtration rate estimation in patients with advanced chronic renal insufficiency based on serum cystatin C levels, Nephron. Clin. Pract., 93, c146, 10.1159/000070234

Locsey, 2001, Homocysteine and cystatin C level changes in haemodialysed patients and connection with cerebro- and cardiovascular complications, Acta Physiol. Hung., 88, 293, 10.1556/APhysiol.88.2001.3-4.11