Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Journal of Biological Chemistry - Tập 280 Số 7 - Trang 5892-5901 - 2005
Fusheng Yang1,2, Giselle P. Lim1,2, Aynun N. Begum1,2, Oliver J. Ubeda1,2, Mychica Simmons1,2, Surendra S. Ambegaokar1,2, Pingping P. Chen1,2, Rakez Kayed3, Charles Glabe3, Sally A. Frautschy1,4,2, Gregory M. Cole1,4,2
1Department of Medicine, UCLA, Los Angeles, California 90095
2Greater Los Angeles Veterans Affairs Healthcare System, Geriatric Research Education and Clinical Center, Sepulveda, California 91343
3Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697-3900
4Department of Neurology, UCLA, Los Angeles, California 90095

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