Cross-reactivity of the BRAF VE1 antibody with epitopes in axonemal dyneins leads to staining of cilia

Modern Pathology - Tập 28 - Trang 596-606 - 2015
Robert T Jones1, Malak S Abedalthagafi1, Mohan Brahmandam2, Edward A Greenfield2, Mai P Hoang3, David N Louis3, Jason L Hornick1, Sandro Santagata1,4
1Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
2Monoclonal Antibody Core, Dana-Farber Cancer Institute and Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, USA
3Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
4Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

Tài liệu tham khảo

Capper, 2012, Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases, Acta Neuropathol, 123, 223, 10.1007/s00401-011-0887-y Capper, 2011, Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody, Acta Neuropathol, 122, 11, 10.1007/s00401-011-0841-z Kato, 2009, A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation, Biochem Biophys Res Commun, 390, 547, 10.1016/j.bbrc.2009.10.001 Capper, 2009, Monoclonal antibody specific for IDH1 R132H mutation, Acta Neuropathol, 118, 599, 10.1007/s00401-009-0595-z Preusser, 2012, Brain metastases: pathobiology and emerging targeted therapies, Acta Neuropathol, 123, 205, 10.1007/s00401-011-0933-9 Preusser, 2011, testing in diagnostic neuropathology: review and practical guideline article invited by the Euro-CNS research committee, Clin Neuropathol, 30, 217, 10.5414/NP300422 Chan, 2013, The utility of immunohistochemistry for providing genetic information on tumors, Int J Surg Pathol, 21, 455, 10.1177/1066896913502529 Santagata, 2014, Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery, Proc Natl Acad Sci USA, 111, 11121, 10.1073/pnas.1404724111 Brastianos, 2014, Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas, Nat Genet, 46, 161, 10.1038/ng.2868 Voelker, 1991, Clinical, radiographic, and pathological features of symptomatic Rathke's cleft cysts, J Neurosurg, 74, 535, 10.3171/jns.1991.74.4.0535 Shin, 1999, Cystic lesions of the pituitary: clinicopathological features distinguishing craniopharyngioma, Rathke's cleft cyst, and arachnoid cyst, J Clin Endocrinol Metab, 84, 3972 Buslei, 2005, Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region, Acta Neuropathol, 109, 589, 10.1007/s00401-005-1004-x MacConaill, 2009, Profiling critical cancer gene mutations in clinical tumor samples, PLoS One, 4, e7887, 10.1371/journal.pone.0007887 Thiru, 2014, Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program, Mol Biol Cell, 25, 1983, 10.1091/mbc.e14-03-0837 Mordes, 2014, VE1 antibody immunoreactivity in normal anterior pituitary and adrenal cortex without detectable BRAF V600E mutations, Am J Clin Pathol, 141, 811, 10.1309/AJCP37TLZLTUAOJL Altschul, 1990, Basic local alignment search tool, J Mol Biol, 215, 403, 10.1016/S0022-2836(05)80360-2 Dias-Santagata, 2011, BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications, PLoS One, 6, e17948, 10.1371/journal.pone.0017948 Lee EQ, Ruland S, LeBoeuf NR et al. Successful treatment of a progressive BRAF V600E-mutated anaplastic pleomorphic xanthoastrocytoma with vemurafenib monotherapy. J Clin Oncol advance online publication, 4 August 2014; 10.1200/jco.2013.51.1766 (e-pub ahead of print). Arisawa, 1989, Effect of estrogen on the response of thyroid stimulating hormone to substance P in rats, Endocrinol Jpn, 36, 899, 10.1507/endocrj1954.36.899 Mitsudomi, 2005, Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence, J Clin Oncol, 23, 2513, 10.1200/JCO.2005.00.992 Yu, 2009, Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer, Clin Cancer Res, 15, 3023, 10.1158/1078-0432.CCR-08-2739 Massi D, Simi L, Sensi E et al. Immunohistochemistry is highly sensitive and specific for the detection of NRASQ61R mutation in melanoma. Mod Pathol advance online publication, 24 October 2014; 10.1038/modpathol.2014.137 (e-pub ahead of print). Carpten, 2007, A transforming mutation in the pleckstrin homology domain of AKT1 in cancer, Nature, 448, 439, 10.1038/nature05933 Brastianos, 2013, Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations, Nat Genet, 45, 285, 10.1038/ng.2526