Cortistatin-17 and -14 exert the same endocrine activities as somatostatin in humans

Growth Hormone & IGF Research - Tập 14 Số 5 - Trang 382-387 - 2004
Cristina Gottero1, Flavia Prodam1, Silvia Destefanis1, Andrea Benso1, Carlotta Gauna2, Elisa Me1, L. Filtri1, Fabrizio Riganti1, Aart‐Jan van der Lely2, Ezio Ghigo1, Fabio Broglio1,2
1Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, c.so Dogliotti 14, 10126 Turin Italy
2Division of Endocrinology, Department of Internal Medicine, Erasmus University of Rotterdam, The Netherlands

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de Lecea, 1996, A cortical neuropeptide with neuronal depressant and sleep-modulating properties, Nature, 381, 242, 10.1038/381242a0

de Lecea, 1997, Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin, Genomics, 42, 499, 10.1006/geno.1997.4763

Fukusumi, 1997, Identification and characterization of a novel human cortistatin-like peptide, Biochem. Biophys. Res. Commun., 232, 157, 10.1006/bbrc.1997.6252

Spier, 2000, Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions, Brain Res. Brain Res. Rev., 33, 228, 10.1016/S0165-0173(00)00031-X

de Lecea, 1997, Cortistatin is expressed in a distinct subset of cortical interneurons, J. Neurosci., 17, 5868, 10.1523/JNEUROSCI.17-15-05868.1997

Dalm, 2003, Cortistatin rather than somatostatin as a potential endogenous ligand for somatostatin receptors in the human immune system, J. Clin. Endocrinol. Metab., 88, 270, 10.1210/jc.2002-020950

Papotti, 2003, Presence of cortistatin in the human pancreas, J. Endocrinol. Invest., 26, RC15, 10.1007/BF03347348

Kreienkamp, 1999, Molecular biology of the receptors for somatostatin and cortistatin, Res. Probl. Cell Different, 26, 215, 10.1007/978-3-540-49421-8_10

Cone, 2003, Neuroendocrinology, 81

Siehler, 1998, [125I]Tyr10-cortistatin14 labels all five somatostatin receptors, Naunyn Schmiedebergs Arch. Pharmacol., 357, 483, 10.1007/PL00005197

Vasilaki, 1999, Cortistatin affects glutamate sensitivity in mouse hypothalamic neurons through activation of sst2 somatostatin receptor subtype, Neuroscience, 88, 359, 10.1016/S0306-4522(98)00413-8

Sanchez-Alavez, 2000, Cortistatin modulates memory processes in rats, Brain Res., 858, 78, 10.1016/S0006-8993(99)02336-7

Calbet, 1999, Cortistatin and somatostatin mRNAs are differentially regulated in response to kainate, Brain Res. Mol. Brain Res., 72, 55, 10.1016/S0169-328X(99)00220-X

Robas, 2003, MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion, J. Biol. Chem., 278, 44400, 10.1074/jbc.M302456200

Deghenghi, 2001, Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland, J. Endocrinol. Invest., 24, RC1, 10.1007/BF03343800

Kojima, 2001, Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor, Horm. Res., 56, 93, 10.1159/000048143

Deghenghi, 2003, Targeting the ghrelin receptor: orally active GHS and cortistatin analogs, Endocrine, 22, 13, 10.1385/ENDO:22:1:13

Kojima, 1999, Ghrelin is a growth-hormone-releasing acylated peptide from stomach, Nature, 402, 656, 10.1038/45230

Muccioli, 2002, Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity, Eur. J. Pharmacol., 440, 235, 10.1016/S0014-2999(02)01432-2

Broglio, 2003, Ghrelin and the endocrine pancreas, Endocrine, 22, 19, 10.1385/ENDO:22:1:19

Broglio, 2002, Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans, J. Clin. Endocrinol. Metab., 87, 4829, 10.1210/jc.2002-020956

Broglio, 2002, Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans, J. Clin. Endocrinol. Metab., 87, 3783, 10.1210/jc.87.8.3783

Benso, 2003, Effects of cortistatin-14 and somatostatin-14 on the endocrine response to hexarelin in humans, J. Endocrinol. Invest., 26, 599, 10.1007/BF03347014

Deghenghi, 2001, Growth hormone-inhibiting activity of cortistatin in the rat, J. Endocrinol. Invest., 24, RC31, 10.1007/BF03343939

Kopchick, 2002, Growth hormone receptor antagonists: discovery, development, and use in patients with acromegaly, Endocr. Rev., 23, 623, 10.1210/er.2001-0022

Barkan, 2003, Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels, J. Clin. Endocrinol. Metab., 88, 2180, 10.1210/jc.2002-021169

Shimada, 2003, Somatostatin suppresses ghrelin secretion from the rat stomach, Biochem. Biophys. Res. Commun., 302, 520, 10.1016/S0006-291X(03)00178-5

Norrelund, 2002, Ghrelin immunoreactivity in human plasma is suppressed by somatostatin, Clin Endocrinol (Oxf), 57, 539, 10.1046/j.1365-2265.2002.01649.x

Arosio, 2003, Stimulatory effects of ghrelin on circulating somatostatin and pancreatic polypeptide levels, J. Clin. Endocrinol. Metab., 88, 701, 10.1210/jc.2002-021161

Broglio, 2003, The endocrine response to ghrelin as a function of gender in humans in young and elderly subjects, J. Clin. Endocrinol. Metab., 88, 1537, 10.1210/jc.2002-021504