Continuous Intravenous Sub-Dissociative Dose Ketamine Infusion for Managing Pain in the Emergency Department

Western Journal of Emergency Medicine - Tập 19 Số 3 - Trang 559-566
Sergey Motov1, Jefferson Drapkin1, Antonios Likourezos1, Tyler Beals1, Ralph Monfort1, Christian Fromm1, John Marshall1
1Maimonides Medical Center, Department of Emergency Medicine, 4802 Tenth Avenue, Brooklyn, NY 11209.

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Tài liệu tham khảo

1. Gao M, Rejaei D, Liu H. Ketamine use in current clinical practice. Acta Pharmacol Sin. 2016;37(7):865-72.

2. Kurdi MS, Theerth KA, Deva RS. Ketamine: Current applications in anesthesia, pain, and critical care. Anesth Essays Res. 2014;8(3):283–9.

3. Tziavrangos E, Schug SA. Clinical pharmacology: other adjuvants. In Macyntyre P et al Clinical Pain Management (Acute Pain), pp: 98-101. Second Edition, 2008 Hodder & Stoughton Limited.

4. Ahern TL, Herring AA, Anderson ES, et al. The first 500: initial experience with widespread use of low-dose ketamine for acute pain management in the ED. Am J Emerg Med. 2015;33(2):197-201.

5. Ahern TL, Herring AA, Miller S, et al. Low-dose ketamine infusion for emergency department patients with severe pain. Pain Med. 2015;16(7):1402–9.

6. Jennings PA, Cameron P, Bernard S. Ketamine as an analgesic in the pre-hospital setting: a systematic review. Acta Anaesthesiol Scand. 2011;55(6):638-43.

7. Lester L, Braude DA, Niles C, et al. Low-dose ketamine for analgesia in the ED: a retrospective case series. Am J Emerg Med. 2010;28(7):820-7.

8. Richards JR and Rockford RE. Low-dose ketamine analgesia: patient and physician experience in the ED. Am J Emerg Med. 2013;31(2):390-4.

9. Beaudoin FL, Lin C, Guan W, et al. Low-dose ketamine improves pain relief in patients receiving intravenous opioids for acute pain in the emergency department: results of a randomized, double-blind, clinical trial. Acad Emerg Med. 2014;21(11):1193-202.

10. Motov S, Rockoff B, Cohen V, et al. Intravenous subdissociative-dose ketamine versus morphine for analgesia in the emergency department: a randomized controlled trial. Ann Emerg Med. 2015;66(3):222–9.

11. Goltser A, Soleyman-Zomalan E, Kresch F, et al. Short (low-dose) ketamine infusion for managing acute pain in the ED: case-report series. Am J Emerg Med. 2015;33(4):601.e5-7.

12. Motov S, Mai M, Pushkar I, et al. A prospective randomized, doubledummy trial comparing intravenous push dose of low dose ketamine to short infusion of low dose ketamine for treatment of moderate to severe pain in the emergency department. Am J Emerg Med. 2017;35(8):1095-100.

13. Sheehy KA, Lippold C, Rice AL, et el. Subanesthetic ketamine for pain management in hospitalized children, adolescents, and young adults: a single-center cohort study. J Pain Res. 2017;10:787-95.

14. Zempsky WT, Loiselle KA, Corsi JM, et al. Use of low-dose ketamine infusion for pediatric patients with sickle cell disease-related pain: a case series. Clin J Pain. 2010;26(2):163-7.

15. Uprety D, Baber A, Foy M. Ketamine infusion for sickle cell pain crisis refractory to opioids: a case report and review of literature. Ann Hematol. 2014;93(5):769-71.

16. Tawfic QA, Eipe N, Penning J. Ultra-low-dose ketamine infusion for ischemic limb pain. Can J Anaesth. 2014;61(1):86-7.