Comparison of pyrrolidides with other amides for mass spectral determination of structure of unsaturated fatty acids
Tóm tắt
Amides of unsaturated fatty acids give mass spectra which indicate the locations of the double bonds. A survey of several amides of oleic acid was made to evaluate which amide might be most suitable for routine use in elucidation of structure. Methods of preparation of several amides of oleic acid are presented with mass spectral and gas chromatographic data. Tertiary amides have most easily interpretable mass psectra which indicate the position of the double bond in the fatty acid chain. The pyrrolidide is advantageous for fatty acid gas liquid chromatography and mass spectrometry analyses because it can be prepared easily in high yield on a microscale, it is volatile enough for gas liquid chromatographic separations, and it has a simple and easily interpretable mass spectrum which indicates the structure.
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