Comparison of Local Recurrence Risk Estimates After Breast-Conserving Surgery for DCIS: DCIS Nomogram Versus Refined Oncotype DX Breast DCIS Score

Kimberly J. Van Zee1, Emily C. Zabor2, Rosemarie Di Donato3, Bryan Harmon3, Jana Fox4, Monica Morrow1, Hiram S. Cody1, Susan Fineberg3
1Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA
2Biostatistics Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, USA
3Department of Pathology, Montefiore Medical Center, Bronx, USA
4Department of Radiation Oncology, Montefiore Medical Center, Bronx, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016;66:7–30.

Worni M, Akushevich I, Greenup R, et al. Trends in treatment patterns and outcomes for ductal carcinoma in situ. J Natl Cancer Inst. 2015;107:djv263.

Correa C, McGale P, et al. Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast. J Natl Cancer Inst Monogr. 2010;41:162–77.

Subhedar P, Olcese C, Patil S, Morrow M, Van Zee KJ. Decreasing recurrence rates for ductal carcinoma in situ: analysis of 2996 women treated with breast-conserving surgery over 30 years. Ann Surg Oncol. 2015;22:3273–81.

McCormick B, Winter K, Hudis C, et al. RTOG 9804: a prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation. J Clin Oncol. 2015;33:709–15.

McCormick B. Randomized trial evaluating radiation following surgical excision for “good risk” DCIS: 12-year report from NRG/RTOG 9804. 2018 ASTRO annual meeting. Abstract no. LBA1 Presented 21 October 2018.

Henson KE, McGale P, Taylor C, Darby SC. Radiation-related mortality from heart disease and lung cancer more than 20 years after radiotherapy for breast cancer. Br J Cancer. 2013;108:179–82.

Rudloff U, Jacks LM, Goldberg JI, et al. Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ. J Clin Oncol. 2010;28:3762–9.

Solin LJ, Gray R, Baehner FL, et al. A multigene expression assay to predict local recurrence risk for ductal carcinoma in situ of the breast. J Natl Cancer Inst. 2013;105:701–10.

Oncotype DX Breast DCIS Score: Clinical evidence. Genomic Health, Redwood City, CA. Retrieved 15 October 2018 https://www.oncotypeiq.com/en-US/breast-cancer/healthcare-professionals/oncotype-dx-breast-dcis-score/clinical-evidence .

Fitzgibbons PL, Bose S, Chen YY, et al. Protocol for the examination of specimens from patients with ductal carcinoma in situ (DCIS) of the breast. College of American Pathologists 2018. Retrieved 26 December 2018 http://www.cap.org/cancerprotocols .

Satagopan JM, Iasonos A, Kanik JG. A reconstructed melanoma data set for evaluating differential treatment benefit according to biomarker subgroups. Data Brief. 2017;12:667–75.

Cronin PA, Olcese C, Patil S, Morrow M, Van Zee KJ. Impact of age on risk of recurrence of ductal carcinoma in situ: outcomes of 2996 women treated with breast-conserving surgery over 30 years. Ann Surg Oncol. 2016;23:2816–24.

Saqi A, Osborne MP, Rosenblatt R, Shin SJ, Hoda SA. Quantifying mammary duct carcinoma in situ: a wild-goose chase? Am J Clin Pathol. 2000;113(Suppl 1):S30–7.

Guidi AJ, Tworek JA, Mais DD, Souers RJ, Blond BJ, Brown RW. Breast specimen processing and reporting with an emphasis on margin evaluation: a College of American Pathologists survey of 866 laboratories. Arch Pathol Lab Med. 2018;142:496–506.

Rakovitch E, Nofech-Mozes S, Hanna W, et al. A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by breast-conserving surgery alone. Breast Cancer Res Treat. 2015;152:389–98.

Paszat L, Sutradhar R, Zhou L, Nofech-Mozes S, Rakovitch E. Including the ductal carcinoma in situ (DCIS) Score in the development of a multivariable prediction model for recurrence after excision of DCIS. Clin Breast Cancer. 2018; 19:35–46

Rakovitch E, Gray R, Baehner FL, et al. Refined estimates of local recurrence risks by DCIS score adjusting for clinicopathological features: a combined analysis of ECOG-ACRIN E5194 and Ontario DCIS cohort studies. Breast Cancer Res Treat. 2018;169:359–69.

Collins LC, Achacoso N, Haque R, et al. Risk prediction for local breast cancer recurrence among women with DCIS treated in a community practice: a nested, case-control study. Ann Surg Oncol. 2015;22(Suppl 3):S502–8.

Sedloev T, Vasileva M, Kundurzhiev T, Hadjieva T. Validation of the Memorial Sloan-Kettering Cancer Center nomogram in the prediction of local recurrence risks after conserving surgery for Bulgarian women with DCIS of the breast. Conference Paper presented at the 2nd world congress on controversies in breast cancer (CoBrCa), Barcelona, Spain, September 2016. Retrieved 22 March 2017 https://www.researchgate.net/publication/312232507_Validation_of_the_Memorial_Sloan-Kettering_Cancer_Center_nomogram_in_the_prediction_of_local_recurrence_risks_after_conserving_surgery_for_Bulgarian_women_with_DCIS_of_the_breast .

Sweldens C, Peeters S, van Limbergen E, et al. Local relapse after breast-conserving therapy for ductal carcinoma in situ: a European single-center experience and external validation of the Memorial Sloan-Kettering Cancer Center DCIS nomogram. Cancer J. 2014;20:1–7.

Wang F, Li H, Tan PH, et al. Validation of a nomogram in the prediction of local recurrence risks after conserving surgery for Asian women with ductal carcinoma in situ of the breast. Clin Oncol R Coll Radiol. 2014;26:684–91.

Yi M, Meric-Bernstam F, Kuerer HM, et al. Evaluation of a breast cancer nomogram for predicting risk of ipsilateral breast tumor recurrences in patients with ductal carcinoma in situ after local excision. J Clin Oncol. 2012;30:600–7.

Marinovich ML, Azizi L, Macaskill P, et al. The association of surgical margins and local recurrence in women with ductal carcinoma in situ treated with breast-conserving therapy: a meta-analysis. Ann Surg Oncol. 2016;23(12):3811–21.

Morrow M, Van Zee KJ, Solin LJ, et al. Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in ductal carcinoma in situ. Ann Surg Oncol. 2016;23:3801–10.

Van Zee KJ, Subhedar P, Olcese C, Patil S, Morrow M. Relationship between margin width and recurrence of ductal carcinoma in situ: analysis of 2996 women treated with breast-conserving surgery for 30 years. Ann Surg. 2015;262:623–31.

Wapnir IL, Dignam JJ, Fisher B, et al. Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS. J Natl Cancer Inst. 2011;103:478–88.

Cuzick J, Sestak I, Pinder SE, et al. Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial. Lancet Oncol. 2011;12:21–9.

Allred DC, Anderson SJ, Paik S, et al. Adjuvant tamoxifen reduces subsequent breast cancer in women with estrogen receptor-positive ductal carcinoma in situ: a study based on NSABP protocol B-24. J Clin Oncol. 2012;30:1268–73.