Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

New England Journal of Medicine - Tập 373 Số 1 - Trang 23-34 - 2015
James Larkin1, Vanna Chiarion‐Sileni2, René González3, Jean‐Jacques Grob4, C. Lance Cowey5, Christopher D. Lao6, Dirk Schadendorf7, Reinhard Dummer8, Michael Smylie9, Piotr Rutkowski10, Pier Francesco Ferrucci11, Andrew G. Hill12, John Wagstaff13, Matteo S. Carlino14,15, John B.A.G. Haanen16, Michele Maio17, Iván Marquez‐Rodas18, Grant A. McArthur19, Paolo A. Ascierto20, Georgina V. Long21,14, Margaret K. Callahan22,23, Michael A. Postow22,23, Kenneth F. Grossmann24, Mario Sznol25, Brigitte Dréno26, Lars Bastholt27, Arvin Yang28, Linda Rollin28, Christine E. Horak29, F. Stephen Hodi30, Jedd D. Wolchok22,23
1Department of Medical Oncology, Royal Marsden Hospital, London
2Melanoma Oncology Unit, Veneto Region Oncology Research Institute, Padua
3Division of Medical Oncology, University of Colorado, Denver, Denver
4Aix-Marseille University, Hôpital de La Timone, Assitance Publique–Hôpitaux de Marseille, Marseille
5Baylor Charles A. Sammons Cancer Center, Dallas, University of Sydney
6Departments of Internal Medicine and Dermatology, University of Michigan, Ann Arbor, University of Sydney
7Department of Dermatology, University of Essen, Essen, Germany, University of Sydney
8University of Zürich Hospital, Zurich, Switzerland, University of Sydney
9Cross Cancer Institute, Edmonton, AB, Canada, University of Sydney
10Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland, University of Sydney
11Oncology of Melanoma Unit, European Institute of Oncology, Milan
12Tasman Oncology Research, Southport Gold Coast, QLD, University of Sydney
13South West Wales Cancer Institute, Singleton Hospital, Swansea
14Melanoma Institute Australia, University of Sydney
15Westmead and Blacktown Hospitals, University of Sydney
16Division of Medical Oncology, the Netherlands Cancer Institute, Amsterdam
17University Hospital of Siena, Siena
18Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid
19Sydney, and Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC
20Istituto Nazionale Tumori Fondazione Pascale, Naples
21Mater Hospital;
22Ludwig Center, Memorial Sloan Kettering Cancer Center
23Weill Cornell Medical College
24Huntsman Cancer Institute, University of Utah, Salt Lake City
25Yale Cancer Center, Smilow Cancer Hospital of the Yale–New Haven Hospital, Yale University School of Medicine, New Haven, CT
26Hôtel Dieu Place Alexis Ricordeau, Nantes
27Department of Oncology, Odense University Hospital, Odense, Denmark
28Bristol-Myers Squibb, Wallingford, CT
29Lawrenceville, NJ
30Dana Farber Cancer Institute, Boston

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Sznol M, 2014, J Clin Oncol, 52, 15