Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial

Wolf, 1991, Atrial fibrillation as an independent risk factor for stroke. The Framingham Study, Stroke, 22, 983, 10.1161/01.STR.22.8.983

Wolf, 1987, Atrial fibrillation: A major contributor to stroke in the elderly. The Framingham Study, Arch Intern Med, 147, 1561, 10.1001/archinte.1987.00370090041008

1994, Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials, Arch Intern Med, 154, 1449, 10.1001/archinte.1994.00420130036007

Hart, 1999, Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis, Ann Intern Med, 131, 492, 10.7326/0003-4819-131-7-199910050-00003

van Walraven, 2002, Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis, JAMA, 288, 2441, 10.1001/jama.288.19.2441

Fuster, 2001, J Am Coll Cardiol, 38, 1231, 10.1016/S0735-1097(01)01587-X

Hirsh, 1998, Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range, Chest, 114, 445S, 10.1378/chest.114.5_Supplement.445S

Bungard, 2000, Why do patients with atrial fibrillation not receive warfarin?, Arch Intern Med, 160, 41, 10.1001/archinte.160.1.41

Patrono, 1998, Platelet-active drugs. The relationships among dose effectiveness, and side effects, Chest, 114, 470S, 10.1378/chest.114.5_Supplement.470S

2001, Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation, N Engl J Med, 345, 494, 10.1056/NEJMoa010746

Steinhubl, 2002, Clopidogrel for the reduction of events during observation. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial, JAMA, 288, 2411, 10.1001/jama.288.19.2411

Chen, 2005, Early intravenous then oral metoprolol in 45 852 patients with acute myocardial infarction: randomized placebo-controlled trial, Lancet, 366, 1622, 10.1016/S0140-6736(05)67661-1

Sabatine, 2005, Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with st-segment elevation, N Engl J Med, 352, 1179, 10.1056/NEJMoa050522

Krumholz, 2006, ACC/AHA clinical performance measures for adults with ST-elevation and non-ST-elevation myocardial infarction, J Am Coll Cardiol, 47, 237, 10.1016/j.jacc.2005.10.020

Gage, 2001, Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation, JAMA, 285, 2864, 10.1001/jama.285.22.2864

Hurlen, 2002, Warfarin, aspirin, or both after myocardial infarction, N Engl J Med, 347, 969, 10.1056/NEJMoa020496

Olsson, 2003, Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial, Lancet, 362, 1691, 10.1016/S0140-6736(03)14841-6

Albers, 2005, Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial, JAMA, 293, 690, 10.1001/jama.293.6.690

1996, Adjusted dose warfarin versus low intensity fixed dose warfarin plus aspirin for high risk patients with atrial fibrillation: The Stroke Prevention in Atrial Fibrillation III randomized clinical trial, Lancet, 348, 633, 10.1016/S0140-6736(96)03487-3