Classification of failure of limb salvage after reconstructive surgery for bone tumours

Bone and Joint Journal - Tập 96-B Số 11 - Trang 1436-1440 - 2014
Eric R. Henderson1, Mary I. O’Connor2, Pietro Ruggieri3, Rein hard Windhager4, Philipp T. Funovics5, C. L. M. H. Gibbons6, Wei Guo7, Henry J. Mankin8, H. Thomas Temple9, G. Douglas Letson10
1Norris Cotton Cancer Center, Musculoskeletal Oncology Program, One Medical Center Drive, Lebanon, PA, 03756, USA.
2ProfessorMayo Clinic, Department of Orthopaedic Surgery, Jacksonville, Florida, USA.
3ProfessorInstituto Ortopedico Rizzoli, Orthopaedic Oncology Division, Bologna, Italy.
4ProfessorUniversity of Vienna, Department of Orthopaedic Surgery, Vienna, Austria.
5Assistant Professor University of Vienna, Department of Orthopaedic Surgery, Vienna, Austria.
6ProfessorOxford University, Orthopaedic Oncology, Oxford University Hospitals, Oxford, UK.
7ProfessorPeople's Hospital, Musculoskeletal Tumor Center, Peking University, Beijing, China.
8Professor Massachusetts General Hospital, Center for Connective Tissue Oncology, Boston, Massachusetts, USA.
9ProfessorUniversity of Miami, Department of Orthopaedic Surgery, Miami, Florida, USA.
10ProfessorMoffitt Cancer Center, Sarcoma Program, Tampa, Florida, USA.

Tóm tắt

Previous classification systems of failure of limb salvage focused primarily on endoprosthetic failures and lacked sufficient depth for the effective study of the causes of failure. In order to address these inadequacies, the International Society of Limb Salvage (ISOLS) formed a committee to recommend revisions of the previous systems. The purpose of this study was to report on their recommendations. The modifications were prepared using an earlier, evidence-based model with subclassification based on the existing medical literature. Subclassification for all five primary types of failure of limb salvage following endoprosthetic reconstruction were formulated and a complementary system was derived for the failure of biological reconstruction. An additional classification of failure in paediatric patients was also described.Limb salvage surgery presents a complex array of potential mechanisms of failure, and a complete and precise classification of types of failure is required. Earlier classification systems lacked specificity, and the evidence-based system outlined here is designed to correct these weaknesses and to provide a means of reporting failures of limb salvage in order to allow the interpretation of outcome following reconstructive surgery.Cite this article: Bone Joint J 2014;96-B:1436–40.

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