Cl? channel inhibition by glibenclamide is not specific for the CFTR-type Cl? channel

Pflügers Archiv - Tập 429 Số 5 - Trang 659-662 - 1995
Alexander Rabe1, J. Disser1, Eberhard Frömter1
1Zentrum der Physiologie, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt, Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Anderson MP, Sheppard DN, Berger HA, Welsh MJ (1992) Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia. Am J Physiol 263:L1-L14

Bear CE, Li C, Kartner N, Bridges RJ, Jensen TJ, Ramjeesingh M, Riordan JR (1992) Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR). Cell 68:809?818

Disser J, Fr�mter E (1993) Intracellular regulation of the outwardly rectifying intermediate conductance Cl-channel in epithelial cell membranes In: Ussing HH, Fischbarg J, Sten-Knudsen O, Hviid Larsen E, Willumsen NJ (eds) Isotonic transport in leaky epithelia. Alfred Benzon Symposium 34, Munksgaard, Copenhagen, pp 147?160

Disser J, Hazama A, Fr�mter E (1993) Chloride channel studies on HT29 cells with minimal levels of cAMP-mediated stimulation. Pfl�gers Arch 422 (suppl 1):R65

Egan M, Flotte T, Afione S, Solow R, Zeitlin PL, Carter BJ, Guggino WB (1992) Defective regulation of outwardly rectifying Cl? channels by protein kinase A corrected by insertion of CFTR. Nature 358:581?584

Hongre A-S, Bar� I, Berthon B, Escande D (1994) Effects of sulphonylureas on cAMP-stimulated Cl? transport via the cystic fibrosis gene product in human epithelial cells. Pfl�gers Arch 426:284?287

Kartner N, Augustinas O, Jensen TJ, Naismith AL, Riordan JR (1992) Mislocalization of DF508 CFTR in cystic fibrosis sweat gland. Nature Genetics 1:321?327

Kunzelmann K, Grolik M, Kubitz R, Greger R (1992) cAMP-dependent activation of small-conductance Cl? channels in HT29 colon carcinoma cells. Pfl�gers Arch 412:230?237

Palmer LG, Frindt G (1986) Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule. Proc Natl Acad Sci USA 83:2767?2770

Sheppard DN, Welsh MJ (1992) Effect of ATP-sensitive K+-channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents. J Gen Physiol 100: 573?591

Sigworth FJ, Sine SM (1987) Data transformations for improved display and fitting of single-channel dwell time histograms. Biophys J 52:1047?1054