Chronic voluntary oral methamphetamine induces deficits in spatial learning and hippocampal protein kinase Mzeta with enhanced astrogliosis and cyclooxygenase-2 levels

Amiry-Moghaddam, 2004, Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport, Neuroscience, 129, 997, 10.1016/j.neuroscience.2004.08.049 Anneken, 2013, MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase, J. Neuroimmune Pharmacol., 8, 58, 10.1007/s11481-012-9420-x Battaglia, 2002, Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity, J. Neurosci., 22, 2135, 10.1523/JNEUROSCI.22-06-02135.2002 Behr, 2000, Dopamine depresses excitatory synaptic transmission onto rat subicular neurons via presynaptic D1-like dopamine receptors, J. Neurophysiol., 84, 112, 10.1152/jn.2000.84.1.112 Belcher, 2008, Methamphetamine influences on recognition memory: comparison of escalating and single-day dosing regimens, Neuropsychopharmacology, 33, 1453, 10.1038/sj.npp.1301510 Belcher, 2005, Impaired object recognition memory following methamphetamine, but not p-chloroamphetamine- or d-amphetamine-induced neurotoxicity, Neuropsychopharmacology, 30, 2026, 10.1038/sj.npp.1300771 Bezzi, 1998, Prostaglandins stimulate calcium-dependent glutamate release in astrocytes, Nature, 391, 281, 10.1038/34651 Bowers, 2010, AMPA receptor synaptic plasticity induced by psychostimulants: the past, present, and therapeutic future, Neuron, 67, 11, 10.1016/j.neuron.2010.06.004 Bowyer, 1994, Further studies of the role of hyperthermia in methamphetamine neurotoxicity, J. Pharmacol. Exp. Ther., 268, 1571 Braren, 2014, Methamphetamine-induced short-term increase and long-term decrease in spatial working memory affects protein Kinase M zeta (PKM(ζ), dopamine, and glutamate receptors, Front. Behav. Neurosci., 8, 438, 10.3389/fnbeh.2014.00438 Cadet, 2009, Molecular bases of methamphetamine-induced neurodegeneration, Int. Rev. Neurobiol., 88, 101, 10.1016/S0074-7742(09)88005-7 Camarasa, 2010, Memantine is a useful drug to prevent the spatial and non-spatial memory deficits induced by methamphetamine in rats, Pharmacol. Res., 62, 450, 10.1016/j.phrs.2010.05.004 Cappon, 2000, Time-course of methamphetamine-induced neurotoxicity in rat caudate-putamen after single-dose treatment, Brain Res., 863, 106, 10.1016/S0006-8993(00)02107-7 Cook, 1993, Pharmacokinetics of methamphetamine self-administered to human subjects by smoking S-(+)-methamphetamine hydrochloride, Drug Metab. Dispos., 21, 717 Cook, 1992, Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans, Drug Metab. Dispos., 20, 856 Farfel, 1992, The N-methyl-D-aspartate antagonist MK-801 protects against serotonin depletions induced by methamphetamine, 3, 4-methylenedioxymethamphetamine and p-chloroamphetamine, Brain Res., 595, 121, 10.1016/0006-8993(92)91460-V Figueiredo-Pereira, 2015, Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration, Front Mol. Neurosci., 7, 104, 10.3389/fnmol.2014.00104 Friedman, 1998, Long-term monoamine depletion, differential recovery, and subtle behavioral impairment following methamphetamine-induced neurotoxicity, Pharmacol. Biochem. Behav., 61, 35, 10.1016/S0091-3057(98)00066-5 Fukumura, 1998, A single dose model of methamphetamine-induced neurotoxicity in rats: effects on neostriatal monoamines and glial fibrillary acidic protein, Brain Res., 806, 1, 10.1016/S0006-8993(98)00656-8 Fumagalli, 1998, Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter, J. Neurosci., 18, 4861, 10.1523/JNEUROSCI.18-13-04861.1998 Geiger, 1995, Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS, Neuron, 15, 193, 10.1016/0896-6273(95)90076-4 Golembiowska, 2003, Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats, Neuropharmacology, 45, 484, 10.1016/S0028-3908(03)00209-0 Goncalves, 2010, Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin, Eur. J. Neurosci., 31, 315, 10.1111/j.1460-9568.2009.07059.x Gonzalez, 2016, Methamphetamine blunts Ca(2 +) currents and excitatory synaptic transmission through D1/5 receptor-mediated mechanisms in the mouse medial prefrontal cortex, Addict. Biol., 21, 589, 10.1111/adb.12249 Green, 1992, The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: evidence for the protective effect of chlormethiazole, Neuropharmacology, 31, 315, 10.1016/0028-3908(92)90062-T Guilarte, 2003, Methamphetamine-induced deficits of brain monoaminergic neuronal markers: distal axotomy or neuronal plasticity, Neuroscience, 122, 499, 10.1016/S0306-4522(03)00476-7 Harris, 1989, Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics, J. Neurosci., 9, 2982, 10.1523/JNEUROSCI.09-08-02982.1989 Hertting, 1989, Formation and function of eicosanoids in the central nervous system, Ann. NY Acad. Sci., 559, 84, 10.1111/j.1749-6632.1989.tb22600.x Heysieattalab, 2016, The effects of GABAA and NMDA receptors in the shell-accumbens on spatial memory of METH-treated rats, Pharmacol. Biochem. Behav., 142, 23, 10.1016/j.pbb.2015.12.008 Hsieh, 2016, Persistent increased PKMzeta in long-term and remote spatial memory, Neurobiol. Learn Mem. Jarrard, 1978, Selective hippocampal lesions: differential effects on performance by rats of a spatial task with preoperative versus postoperative training, J. Comp. Physiol. Psychol., 92, 1119, 10.1037/h0077516 Jessen, 2015, The glymphatic system: a beginner’s guide, Neurochem. Res., 40, 2583, 10.1007/s11064-015-1581-6 Kalivas, 2011, New medications for drug addiction hiding in glutamatergic neuroplasticity, Mol. Psychiatry, 16, 974, 10.1038/mp.2011.46 Keith, 2013, Time of day influences the voluntary intake and behavioral response to methamphetamine and food reward, Pharmacol. Biochem. Behav., 110, 117, 10.1016/j.pbb.2013.05.011 Kelley, 1999, Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2, Am. J. Pathol., 155, 995, 10.1016/S0002-9440(10)65199-1 Kisilevsky, 2008, D1 receptors physically interact with N-type calcium channels to regulate channel distribution and dendritic calcium entry, Neuron, 58, 557, 10.1016/j.neuron.2008.03.002 Kondo, 2002, 15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis, Proc. Natl. Acad. Sci. USA, 99, 7367, 10.1073/pnas.112212599 Lai, 2006, Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking, J. Neurosci., 26, 11798, 10.1523/JNEUROSCI.2084-06.2006 Lakens, 2013, Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs, Front. Psychol., 4, 863, 10.3389/fpsyg.2013.00863 LaVoie, 2004, Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity, Exp. Neurol., 187, 47, 10.1016/j.expneurol.2004.01.010 Lee, 2002, Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor, Cell, 111, 219, 10.1016/S0092-8674(02)00962-5 Leitão, 2017, Aquaporin-4 as a New Target against Methamphetamine-Induced Brain Alterations: Focus on the Neurogliovascular Unit and Motivational Behavior, Mol. Neurobiol., 1 Leuner, 2003, Associative memory formation increases the observation of dendritic spines in the hippocampus, J. Neurosci., 23, 659, 10.1523/JNEUROSCI.23-02-00659.2003 Li, 2004, Neurotoxic prostaglandin J2 enhances cyclooxygenase-2 expression in neuronal cells through the p38MAPK pathway: a death wish?, J. Neurosci. Res., 78, 824, 10.1002/jnr.20346 Li, 2004, Delta12-Prostaglandin J2 inhibits the ubiquitin hydrolase UCH-L1 and elicits ubiquitin-protein aggregation without proteasome inhibition, Biochem. Biophys. Res. Commun., 319, 1171, 10.1016/j.bbrc.2004.05.098 Liang, 2005, Prostaglandin D2 mediates neuronal protection via the DP1 receptor, J. Neurochem., 92, 477, 10.1111/j.1471-4159.2004.02870.x Ling, 2002, Protein kinase Mzeta is necessary and sufficient for LTP maintenance, Nat. Neurosci., 5, 295, 10.1038/nn829 Lorez, 1981, Fluorescence histochemistry indicates damage of striatal dopamine nerve terminals in rats after multiple doses of methamphetamine, Life Sci., 28, 911, 10.1016/0024-3205(81)90053-9 Mark, 2004, High-dose methamphetamine acutely activates the striatonigral pathway to increase striatal glutamate and mediate long-term dopamine toxicity, J. Neurosci., 24, 11449, 10.1523/JNEUROSCI.3597-04.2004 Marrone, 2007, Ultrastructural plasticity associated with hippocampal-dependent learning: a meta-analysis, Neurobiol. Learn Mem., 87, 361, 10.1016/j.nlm.2006.10.001 Marshall, 2007, Methamphetamine-induced neural and cognitive changes in rodent, Addiction, 102, 61, 10.1111/j.1360-0443.2006.01780.x Marshall, 1993, Dopamine-glutamate interactions in methamphetamine-induced neurotoxicity, J. Neural. Transm. Gen. Sect., 91, 241, 10.1007/BF01245234 Masuda, 1986, Protective effect of prostaglandins D2, E1 and I2 against cerebral hypoxia/anoxia in mice, Naunyn Schmiedebergs Arch. Pharmacol., 334, 282, 10.1007/BF00508783 McCann, 2008, Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users, Synapse, 62, 91, 10.1002/syn.20471 McConnell, 2015, Characterization of binge-dosed methamphetamine-induced neurotoxicity and neuroinflammation, Neurotoxicology, 50, 131, 10.1016/j.neuro.2015.08.006 McCullough, 2004, Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia, J. Neurosci., 24, 257, 10.1523/JNEUROSCI.4485-03.2004 Migues, 2010, PKMzeta maintains memories by regulating GluR2-dependent AMPA receptor trafficking, Nat. Neurosci., 13, 630, 10.1038/nn.2531 Miyagishi, 2017, Increased Expression of 15-Hydroxyprostaglandin Dehydrogenase in Spinal Astrocytes During Disease Progression in a Model of Amyotrophic Lateral Sclerosis, Cell Mol. Neurobiol., 37, 445, 10.1007/s10571-016-0377-9 Moser, 1994, An increase in dendritic spine density on hippocampal CA1 pyramidal cells following spatial learning in adult rats suggests the formation of new synapses, Proc. Natl. Acad. Sci. USA, 91, 12673, 10.1073/pnas.91.26.12673 Narita, 2005, Long-lasting change in brain dynamics induced by methamphetamine: enhancement of protein kinase C-dependent astrocytic response and behavioral sensitization, J. Neurochem., 93, 1383, 10.1111/j.1471-4159.2005.03097.x NIDA, 2013 Nogues, 1994, Protein kinase C activity in the hippocampus following spatial learning tasks in mice, Hippocampus, 4, 71, 10.1002/hipo.450040109 North, 2013, Chronic methamphetamine exposure produces a delayed, long-lasting memory deficit, Synapse, 67, 245, 10.1002/syn.21635 Northrop, 2013, Cyclooxygenase activity contributes to the monoaminergic damage caused by serial exposure to stress and methamphetamine, Neuropharmacology, 72, 96, 10.1016/j.neuropharm.2013.04.040 Novak, 2011, Comparing injection and non-injection routes of administration for heroin, methamphetamine, and cocaine users in the United States, J. Addict. Dis., 30, 248, 10.1080/10550887.2011.581989 O'Callaghan, 1994, Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse, J. Pharmacol. Exp. Ther., 270, 741 O'Callaghan, 2005, Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity, Expert Opin. Drug Saf., 4, 433, 10.1517/14740338.4.3.433 O'Neil, 2006, Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge, Synapse, 60, 465, 10.1002/syn.20320 Obermeit, 2013, Attention-deficit/hyperactivity disorder among chronic methamphetamine users: frequency, persistence, and adverse effects on everyday functioning, Addict. Behav., 38, 2874, 10.1016/j.addbeh.2013.08.010 Ogburn, 2006, Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates, J. Biol. Chem., 281, 23274, 10.1074/jbc.M600635200 Olsen, 2013, Impaired memory and reduced sensitivity to the circadian period lengthening effects of methamphetamine in mice selected for high methamphetamine consumption, Behav. Brain Res., 256, 197, 10.1016/j.bbr.2013.08.015 Olton, 1979, Spatial memory and hippocampal function, Neuropsychologia, 17, 669, 10.1016/0028-3932(79)90042-3 Pastalkova, 2006, Storage of spatial information by the maintenance mechanism of LTP, Science, 313, 1141, 10.1126/science.1128657 Rau, 2016, The neuroprotective potential of low-dose methamphetamine in preclinical models of stroke and traumatic brain injury, Prog. Neuropsychopharmacol. Biol. Psychiatry, 64, 231, 10.1016/j.pnpbp.2015.02.013 Ricaurte, 1982, Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain, Brain Res., 235, 93, 10.1016/0006-8993(82)90198-6 Ricaurte, 1984, Further evidence that amphetamines produce long-lasting dopamine neurochemical deficits by destroying dopamine nerve fibers, Brain Res., 303, 359, 10.1016/0006-8993(84)91221-6 Riddle, 2002, Tolerance to the neurotoxic effects of methamphetamine in young rats, Eur. J. Pharmacol., 435, 181, 10.1016/S0014-2999(01)01592-8 Sacktor, 2011, How does PKMzeta maintain long-term memory?, Nat. Rev. Neurosci., 12, 9, 10.1038/nrn2949 Sang, 2011, SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons, Toxicol. Sci., 124, 400, 10.1093/toxsci/kfr224 Sebastian, 2013, Robust training attenuates TBI-induced deficits in reference and working memory on the radial 8-arm maze, Front. Behav. Neurosci., 7, 38, 10.3389/fnbeh.2013.00038 Sebastian, 2013, Acute physiological stress promotes clustering of synaptic markers and alters spine morphology in the hippocampus, PLoS One, 8, 10.1371/journal.pone.0079077 Sebastian, 2013, PKMzeta differentially utilized between sexes for remote long-term spatial memory, PLoS One, 8, 10.1371/journal.pone.0081121 Segal, 2003, Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge, Neuropsychopharmacology, 28, 1730, 10.1038/sj.npp.1300247 Sekine, 2008, Methamphetamine causes microglial activation in the brains of human abusers, J. Neurosci., 28, 5756, 10.1523/JNEUROSCI.1179-08.2008 Serrano, 2008, PKMzeta maintains spatial, instrumental, and classically conditioned long-term memories, PLoS Biol., 6, 2698, 10.1371/journal.pbio.0060318 Serrano, 2005, Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation, J. Neurosci., 25, 1979, 10.1523/JNEUROSCI.5132-04.2005 Shibasaki, 2011, Role of actin depolymerizing factor in the development of methamphetamine-induced place preference in mice, Eur. J. Pharmacol., 671, 70, 10.1016/j.ejphar.2011.09.176 Simoes, 2007, Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory, Neuroscience, 150, 433, 10.1016/j.neuroscience.2007.09.044 Smith, 2000, Cyclooxygenases: structural, cellular and molecular biology, Annu. Rev. Biochem., 69, 145, 10.1146/annurev.biochem.69.1.145 Surmeier, 1995, Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons, Neuron, 14, 385, 10.1016/0896-6273(95)90294-5 Suzuki, 2003, Recent advances in the study of AMPA receptors, Nihon Yakurigaku Zasshi, 122, 515, 10.1254/fpj.122.515 Taniguchi, 2007, Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury, J. Neurosci., 27, 4303, 10.1523/JNEUROSCI.0321-07.2007 Thomas, 2005, Cyclooxygenase-2 is an obligatory factor in methamphetamine-induced neurotoxicity, J. Pharmacol. Exp. Ther., 313, 870, 10.1124/jpet.104.080242 Thompson, 2004, Structural abnormalities in the brains of human subjects who use methamphetamine, J. Neurosci., 24, 6028, 10.1523/JNEUROSCI.0713-04.2004 Toyomoto, 2004, Prostaglandins are powerful inducers of NGF and BDNF production in mouse astrocyte cultures, FEBS Lett., 562, 211, 10.1016/S0014-5793(04)00246-7 Tsokas, 2016, Compensation for PKMzeta in long-term potentiation and spatial long-term memory in mutant mice, Elife, 5 Tsuji, 2009, Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen, Neurochem. Res., 34, 764, 10.1007/s11064-008-9863-x UN, 2008 UN, 2011 Van Damme, 2005, GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis, J. Neuropathol. Exp. Neurol., 64, 605, 10.1097/01.jnen.0000171647.09589.07 Vierck, 2000, Evaluating dot and Western blots using image analysis and pixel quantification of electronic images, Methods Cell Sci., 22, 313, 10.1023/A:1017581302281 Volkow, 2015, Recovery of dopamine transporters with methamphetamine detoxification is not linked to changes in dopamine release, Neuroimage, 121, 20, 10.1016/j.neuroimage.2015.07.035 Wang, 2006, Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells, J. Biol. Chem., 281, 21377, 10.1074/jbc.M601201200 Weber, 2017, Aggression in group-housed laboratory mice: why can’t we solve the problem?, Nature, 20, 1 Williams, 2003, Developmental D-methamphetamine treatment selectively induces spatial navigation impairments in reference memory in the Morris water maze while sparing working memory, Synapse, 48, 138, 10.1002/syn.10159 Xu, 2005, Induction of striatal pre- and postsynaptic damage by methamphetamine requires the dopamine receptors, Synapse, 58, 110, 10.1002/syn.20185 Yan, 2015, Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome, Cell, 160, 62, 10.1016/j.cell.2014.11.047 Yao, 2008, PKM zeta maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors, J. Neurosci., 28, 7820, 10.1523/JNEUROSCI.0223-08.2008 Zhang, 2007, Selective inhibition of cyclooxygenase-2 exacerbates methamphetamine-induced dopamine depletion in the striatum in rats, Neuroscience, 150, 950, 10.1016/j.neuroscience.2007.09.059 Zhu, 2007, Glial fibrillary acidic protein-expressing cells in the neurogenic regions in normal and injured adult brains, J. Neurosci. Res., 85, 2783, 10.1002/jnr.21257 Zhu, 2005, Disparity in the temporal appearance of methamphetamine-induced apoptosis and depletion of dopamine terminal markers in the striatum of mice, Brain Res., 1049, 171, 10.1016/j.brainres.2005.04.089