Franz Fazekas1, Frederik Barkhof2, Lars‐Olof Wahlund3, Leonardo Pantoni4, Timo Erkinjuntti5, Philip Scheltens6, Reinhold Schmidt7
1Department of Neurology and MR Center, Karl-Franzens University, Graz, Austria.
2Radiology and Nuclear Medicine
3Karolinska Institutet
4University of Florence
5Memory Research Unit
6Neurology,
7University of Graz.
Tóm tắt
Rating scales play an important role in the evaluation of computed tomography (CT) or magnetic resonance-detected white matter lesions (WML). Unfortunately, this type of visual semiquantitative assessment is not yet an optimal tool because commonly agreed concepts regarding its use are lacking. To generate a discussion platform for further improvement of CT and MRI rating, we will provide some basic definitions, summarize the advantages and disadvantages of scoring schemes and review current efforts towards the improvement of this tool. Future research will have to concentrate on deepening our understanding of the histopathologic substrates of WML and on strategies to document their progression.
