COVID-19 Vaccine Acceptance, Hesitancy, and Resistancy among University Students in France

Vaccines - Tập 9 Số 6 - Trang 654
Marie‐Pierre Tavolacci1,2,3,4, Pierre Déchelotte2,3,5,4, J. Ladner6,2,3,4
1Centre d'Investigation Clinique [CHU Rouen]
2Institute for Research and Innovation in Biomedicine
3Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau
4UNIROUEN - UFR Santé
5Service de nutrition [CHU Rouen]
6Département d'épidémiologie et de promotion de la santé [Rouen]

Tóm tắt

The objectives were to explore, among university students, the level of COVID-19 vaccine acceptance, hesitancy, and resistancy and to determine the motivations and barriers, and the reasons that may change student vaccination decision making. An online observational cross-sectional study was conducted among students of a French university in January 2021 with questions about the intention to be vaccinated against COVID-19, the motivations and the barriers. The convenience sample included 3089 students, with a mean of age of 20.3 (SD = 1.9). To the question on the intention to vaccinate against the COVID-19, 58.0% of students reported that they would choose to have a vaccination, 17.0% reported that they would not and 25.0% were not sure. The main motivations for vaccine acceptance were “I don′t want to transmit COVID-19 to others”, the main barriers for vaccine resistance or hesitancy were “I prefer to wait until I have more experience with these new vaccines”. Age, female gender, being in first three years of study, studied sciences courses and neither sciences nor healthcare courses of study were significantly associated with a higher risk of vaccine hesitancy or resistancy. Self-estimated knowledge of conventional vaccines and COVID-19 vaccines, and confidence in efficiency and safety of conventional vaccination were associated with a lower risk of vaccine hesitancy or resistancy. It is relevant to disseminate evidence-based interventions to promote COVID-19 vaccine acceptability for college students, especially for the students in neither sciences nor healthcare courses of study, as college students will soon be eligible to receive a COVID-19 vaccine.

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Tài liệu tham khảo

World Health Organization (2021, April 28). World Health Organization COVID-19 Dashboard. Available online: https://covid19.who.int/.

European Medicines Agency (2021, March 25). COVID-19 Vaccines, Available online: https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/treatments-vaccines/covid-19-vaccines.

Harrison, 2020, Vaccine confidence in the time of COVID-19, Eur. J. Epidemiol., 35, 325, 10.1007/s10654-020-00634-3

(2021, March 25). Ministère Des Solidarités et de la Santé. Available online: https://solidarites-sante.gouv.fr/grands-dossiers/vaccin-covid-19/publics-prioritaires-vaccin-covid-19.

Chou, 2020, Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers, Ann. Intern. Med., 173, 120, 10.7326/M20-1632

Han, 2020, COVID-19: Insight into the asymptomatic SARS-COV-2 infection and transmission, Int. J. Biol. Sci., 15, 2803, 10.7150/ijbs.48991

Guilamo-Ramos, V., Benzekri, A., Thimm-Kaiser, M., Hidalgo, A., and Perlman, D.C. (2020). Reconsidering Assumptions of Adolescent and Young Adult Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Dynamics. Clin. Infect. Dis.

Zheng, 2020, 2020 Risk factors of critical and mortal COVID-19 cases: A systematic literature review and meta-analysis, J. Infect., 8, e16, 10.1016/j.jinf.2020.04.021

Figliozzi, 2020, Predictors of adverse prognosis in COVID-19: A systematic review and meta-analysis, Eur. J. Clin. Investig., 10, e13362, 10.1111/eci.13362

Lu, H., Weintz, C., Pace, J., Indana, D., Linka, K., and Kuhl, E. (2021). Are college campuses superspreaders? A data-driven modeling study. Comput. Methods Biomech. Biomed. Eng., 1–11.

Lin, C., Tu, P., and Beitsch, L.M. (2021). Confidence and Receptivity for COVID-19 Vaccines: A Rapid Systematic Review. Vaccines, 9.

(2021, March 25). Global Attitudes on a COVID-19 Vaccine. Ipsos Survey for The World Economic Forum. Available online: https://www.ipsos.com/en-ro/global-attitudes-covid-19-vaccine-january-2021.

MacDonald, 2015, Vaccine hesitancy: Definition, scope and determinants, Vaccine, 33, 4161, 10.1016/j.vaccine.2015.04.036

Betsch, C., Schmid, P., Heinemeier, D., Korn, L., Holtmann, C., and Böhm, R. (2018). Beyond confidence: Development of a measure assessing the 5C psychological antecedents of vaccination. PLoS ONE, 13.

Lane, 2018, Vaccine hesitancy around the globe: Analysis of three years of WHO/UNICEF Joint Reporting Form data-2015–2017, Vaccine, 36, 3861, 10.1016/j.vaccine.2018.03.063

Laberge, 2013, Vaccine hesitancy: An overview, Hum. Vaccines Immunother., 8, 1763

Dror, 2020, Vaccine hesitancy: The next challenge in the fight against COVID-19, Eur. J. Epidemiol., 35, 775, 10.1007/s10654-020-00671-y

Detoc, 2020, Intention to participate in a COVID-19 vaccine clinical trial and to get vaccinated against COVID-19 in France during the pandemic, Vaccine, 38, 7002, 10.1016/j.vaccine.2020.09.041

Kreps, 2020, Factors Associated with US Adults’ Likelihood of Accepting COVID-19 Vaccination, JAMA Netw. Open, 10, e2025594, 10.1001/jamanetworkopen.2020.25594

Lin, Y., Hu, Z., Zhao, Q., Alias, H., Danaee, M., and Wong, L.P. (2020). Understanding COVID-19 vaccine demand and hesitancy: A nationwide online survey in China. PLoS Negl. Trop. Dis., 14.

Suresh, P.S., Thejaswini, V., and Rajan, T. (2011). Factors associated with 2009 pandemic influenza A (H1N1) vaccination acceptance among university students from India during the post-pandemic phase. BMC Infect. Dis., 11.

Barello, 2020, ‘Vaccine hesitancy’ among university students in Italy during the COVID-19 pandemic, Eur. J. Epidemiol., 35, 781, 10.1007/s10654-020-00670-z

Saied, 2021, Vaccine Hesitancy: Beliefs and Barriers Associated with COVID-19 Vaccination among Egyptian Medical Students, Med. Virol., 93, 4280, 10.1002/jmv.26910

Lucia, V.C., Kelekar, A., and Afonso, N.M. (2020). COVID-19 vaccine hesitancy among medical students. J. Public Health, 230.

Montagni, I., Ouazzani-Touhami, K., Mebarki, A., Texier, N., Schück, S., Tzourio, C., and The Confins Group (2021). Acceptance of a Covid-19 vaccine is associated with ability to detect fake news and health literacy. J. Public Health.

Grech, V., and Gauci, C. (2020). WITHDRAWN: Vaccine hesitancy in the University of Malta Faculties of Health Sciences, Dentistry and Medicine vis-à-vis influenza and novel COVID-19 vaccination. Early Hum. Dev., 105258.

Verger, 2015, Vaccine Hesitancy Among General Practitioners and Its Determinants During Controversies: A National Cross-sectional Survey in France, EBioMedicine, 2, 891, 10.1016/j.ebiom.2015.06.018

Lepiller, 2020, Perceptions of French healthcare students of vaccines and the impact of conducting an intervention in health promotion, Vaccine, 38, 6794, 10.1016/j.vaccine.2020.08.036

Jacquet, 2017, Pulcini On behalf of the EDUVAC Study Group Vaccine Education of Medical Students: A Nationwide Cross-sectional Survey, Am. J. Prev. Med., 3, e97

Baicker, 2020, Using social and behavioural science to support COVID-19 pandemic response, Nat. Hum. Behav., 5, 460

Karlsson, L.C., Lewandowsky, S., Antfolk, J., Salo, P., Lindfelt, M., Oksanen, T., Kivimäki, M., and Soveri, A. (2019). The association between vaccination confidence, vaccination behavior, and willingness to recommend vaccines among Finnish healthcare workers. PLoS ONE, 14.

Vulpe, 2021, Social amplification of risk and “probable vaccine damage”: A typology of vaccination beliefs in 28 European countries, Vaccine, 39, 1508, 10.1016/j.vaccine.2021.01.063

Kreps, 2021, Public attitudes toward COVID-19 vaccination: The role of vaccine attributes, incentives, and misinformationPublic attitudes toward COVID-19 vaccination: The role of vaccine attributes, incentives, and misinformation, npj Vaccines, 6, 73, 10.1038/s41541-021-00335-2

Palamenghi, 2020, Mistrust in biomedical research and vaccine hesitancy: The forefront challenge in the battle against COVID-19 in Italy, Eur. J. Epidemiol., 35, 785, 10.1007/s10654-020-00675-8

Latkin, C.A., Dayton, L., Yi, G., Colon, B., and Kong, X. (2021). Mask usage, social distancing, racial, and gender correlates of COVID-19 vaccine intentions among adults in the US. PLoS ONE, 16.

Korhonen, 2013, Low measles vaccination coverage among medical residents in Marseille, France: Reasons for non-vaccination, Eur. J. Public Health, 3, 512

Viswanath, K., Bekalu, M., Dhawan, D., Pinnamaneni, R., Lang, J., and McLoud, R. (2021). Individual and social determinants of COVID-19 vaccine uptake. BMC Public Health, 21.

Schwarzinger, 2021, COVID-19 vaccine hesitancy in a representative working-age population in France: A survey experiment based on vaccine characteristics, Lancet Public Health, 6, e210, 10.1016/S2468-2667(21)00012-8

Rodas, 2012, Exploring predictors influencing intended and actual acceptability of the A/H1N1 pandemic vaccine: A cohort study of university students in Hong Kong, Public Health, 126, 1007, 10.1016/j.puhe.2012.09.011

Karafillakis, 2016, Vaccine hesitancy among healthcare workers in Europe: A qualitative study, Vaccine, 34, 5013, 10.1016/j.vaccine.2016.08.029

Smith, 2019, Mapping the anti-vaccination movement on Facebook, Inf. Commun. Soc., 22, 1310, 10.1080/1369118X.2017.1418406

Germani, F., and Biller-Andorno, N. (2021). The anti-vaccination infodemic on social media: A behavioral analysis. PLoS ONE, 16.

Edwards, B., Biddle, N., Gray, M., and Sollis, K. (2021). COVID-19 vaccine hesitancy and resistance: Correlates in a nationally representative longitudinal survey of the Australian population. PLoS ONE, 16.

Johnson, D.K., Mello, E.J., Walker, T.D., Hood, S.J., Jensen, J.L., and Poole, B.D. (2019). Combating Vaccine Hesitancy with Vaccine-Preventable Disease Familiarization: An Interview and Curriculum Intervention for College Students. Vaccines, 7.

Paterson, 2016, Vaccine hesitancy and healthcare providers, Vaccine, 34, 6700, 10.1016/j.vaccine.2016.10.042

Marco-Franco, J.M., Pita-Barros, P., Vivas-Orts, D., González-de-Julián, S., and Vivas-Consuelo, D. (2021). COVID-19, Fake News, and Vaccines: Should Regulation Be Implemented?. Int. J. Environ. Res. Public Health, 18.

Montagni, 2020, Gamification is an innovative and promising option to consider when designing vaccination-related interventions addressed to the general public and young people in particular, especially for those who are hesitant about vaccination, JMIR Serious Games, 2, e16983, 10.2196/16983

Université de Rouen Normandie (2021, April 22). Available online: https://www.univ-rouen.fr/.

French, J., Deshpande, S., Evans, W., and Obregon, R. (2020). Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion Strategy. Int. J. Environ. Res. Public Health, 17.

World Health Organization (2020). Behavioral Considerations for Acceptance and Uptake of COVID-19 Vaccines: WHO Technical Advisory Group on Behavioral Insights and Sciences for Health, Meeting Report, 15 October 2020, World Health Organization. Available online: https://apps.who.int/iris/handle/10665/337335.

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Vaccines

Tập 9 Số 6

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