Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

Salomone Di Saverio1, Fausto Catena2, Marica Galati1, Nazareno Smerieri1, Walter L. Biffl3, Luca Ansaloni2, Gregorio Tugnoli1, George C. Velmahos4, Massimo Sartelli5, Cino Bendinelli6, Gustavo Pereira Fraga7, Michael D. Kelly8, Frederick A. Moore9, Vincenzo Mandalà10, Stefano Mandalà10, Michele Masetti1, Elio Jovine1, Antonio Pinna11, Andrew B. Peitzman12, Ari Leppäniemi13, Paul H. Sugarbaker14, Harry van Goor15, Ernest E. Moore3, J Jeekel16, Fausto Catena17
1Emergency and Trauma Surgery Unit, Departments of Emergency and Surgery, Maggiore Hospital Trauma Center, Bologna, Italy
2General Surgery I, Ospedali Riuniti di Bergamo, Bergamo, Italy
3Department of Surgery, Denver Health, University of Colorado Health Sciences Denver, Denver Health Medical Center, 777 Bannock Street, Denver, CO, 80204, USA
4Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
5Department of Surgery, Macerata Hospital, Via Santa Lucia 2, Macerata, 62100, Italy
6Department of Surgery, John Hunter Hospital and University of Newcastle, Locke Bag 1 Hunter Region Maile Centre, Newcastle, NSW, 2310, Australia
7Division of Trauma Surgery, University of Campinas, Campinas, SP, Brazil
8Upper GI Unit, Department of Surgery, Frenchay Hospital, North Bristol, NHS Trust, Bristol, UK
9Department of Surgery, University of Florida, Gainesville, FL, 32610-0254, USA
10Department of General and Emergency Surgery, Associated Hospitals “Villa Sofia - Cervello”, Palermo, Italy
11Emergency Surgery Unit, Department of General and Multivisceral Transplant Surgery, S Orsola Malpighi University Hospital, Bologna, Italy
12Division of General Surgery, University of Pittsburgh Physicians, Pittsburgh, 15213 PA, USA
13Emergency Surgery, Department of Abdominal Surgery, Meilahti Hospital, University of Helsinki, Haartmaninkatu 4, 340, Helsinki, FIN-00029 HUS, Finland
14Washington Cancer Institute, Washington Hospital Center, Washington, DC, 20010, USA
15Department of Surgery, Radboud University Nijmegen Medical Centre, P.O. box 9101, 6500, HB Nijmegen, The Netherlands
16Department of Surgery, Erasmus University Medical Center, PO Box 2040 3000, Rotterdam, CA, The Netherlands
17Department of Emergency and Trauma Surgery, Maggiore Hospital of Parma, Parma, Italy

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Parker C, Ellis H, Moran BJ: Postoperative adhesions: ten-year followup of 12,584 patients undergoing lower abdominal surgery. Dis Colon Rectum. 2001, 44: 822-830. 10.1007/BF02234701.

Ellis: The magnitude of adhesion related problems. Ann Chir Gynaecol. 1998, 87: 9-11.

Zielinski MD, Bannon MP: Current management of small bowel obstruction. Adv in Surg. 2011, 45: 1-29. 10.1016/j.yasu.2011.03.017.

Galinos B, Branco BC, Beat S, Lydia L, Kenji I, Demetrios D: The incidence and risk factors of post-laparotomy adhesive small bowel obstruction. J Gastrointest Surg. 2010, 14: 1619-1628. 10.1007/s11605-010-1189-8. doi:10.1007/s11605-010-1189-8

Reschef A, Hull TL, Kiran RP: Risk of adhesive obstruction after colorectal surgery: the benefits of the minimally invasive approach may extend well beyond the perioperative period. Surg Endosc. 2013, 27: 1717-1720. 10.1007/s00464-012-2663-z. doi:10.1007/s00464-012-2663-z

Parker C, Wilson MS, Menzies D: The SCAR-3 study: 5-year adhesionrelated readmission risk following lower abdominal surgical procedures. Colorectal Dis. 2005, 7: 551-558. 10.1111/j.1463-1318.2005.00857.x.

Stewart RM, Page CP, Brender J: The incidence and risk of early postoperative small bowel obstruction: a cohort study. Am J Surg. 1987, 154: 643-647. 10.1016/0002-9610(87)90234-0.

Howard B, Steven W, Ozeran S: Factors predicting the recurrence of adhesive small-bowel obstruction. Am J Surg. 1995, 170 (4): 361-365. 10.1016/S0002-9610(99)80304-3.

Barkan Webster S, Ozeran S: Factors predicting the recurrence of adhesive small-bowel obstruction. Am J Surg. 1995, 170: 361-365. 10.1016/S0002-9610(99)80304-3.

Miller G, Boman J, Shrier I, Gordon PH: Natural history of patients with adhesive small bowel obstruction. Br J Surg. 2000, 87 (9): 1240-1247. 10.1046/j.1365-2168.2000.01530.x.

Di Saverio S, Tugnoli G, Orlandi PE, Catena F: A 73-year-old man with long-term immobility presenting with abdominal pain. PLoS Med. 2009, 6: e1000092-10.1371/journal.pmed.1000092.

Obuz F, Terzi C, Sokmen S, Yilmaz E, Yildiz D, Fuzun M: The efficacy of helical CT in the diagnosis of small bowel obstruction. Eur J Radiol. 2003, 48 (3): 299-304. 10.1016/S0720-048X(02)00382-0.

Trésallet C, Lebreton N, Royer B, Leyre P, Godiris-Petit G, Menegaux F: Improving the management of acute adhesive small bowel obstruction with CT-scan and water-soluble contrast medium: a prospective study. Dis Colon Rectum. 2009, 52 (11): 1869-1876. 10.1007/DCR.0b013e3181b35c06.

Zalcman M, Sy M, Donckier V, Closset J, Gansbeke DV: Helical CT signs in the diagnosis of intestinal ischemia in small-bowel obstruction. AJR Am J Roentgenol. 2000, 175 (6): 1601-1607. 10.2214/ajr.175.6.1751601.

Grassi R, Romano S, D’Amario F: The relevance of free fluid between intestinal loops detected by sonography in the clinical assessment of small bowel obstruction in adults. Eur J Radiol. 2004, 50 (1): 5-14. 10.1016/j.ejrad.2003.11.009.

Choi HK, Chu KW, Law WL: Therapeutic value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective randomized trial. Ann Surg. 2002, 236: 1-6. 10.1097/00000658-200207000-00002.

Srinivasa S, Thakore N, Abbas S, Mahmood M, Kahokehr AA, Hill AG: Impact of Gastrografin in clinical practice in the management of adhesive small bowel obstruction. Can J Surg. 2011, 54 (2):

Wadani HAI, Al Awad NI, Hassan KA, Zakaria HM, Al Mulhim AA, Alaqeel FO: Role of water soluble contrast agents in assigning patients to a non-operative course in adhesive small bowel obstruction. Oman Med J. 2011, 26 (6): 454-456. 10.5001/omj.2011.116. doi:10.5001/omj.2011.116

Di Saverio S, Catena F, Ansaloni L, Gavioli M, Valentino M, Pinna AD: Watersoluble contrast medium (gastrografin) value in adhesive small intestine obstruction (ASIO): a prospective, randomized, controlled, clinical trial. World J Surg. 2008, 32 (10): 2293-2304. 10.1007/s00268-008-9694-6.

Barkan H, Webster S, Ozeran S: Factors predicting the recurrence of adhesive small-bowel obstruction. Am J Surg. 1995, 70: 361-365.

Ivy L, Shing W, Wong P, Malouf P, Truskett G: Effect of handover on the outcomes of small bowel obstruction in an acute care surgery model. ANZ J Surg. 2012, 10.1111/j.1445-2197.2012.06248.x

Leung AM, Vu H: Factors predicting need for and delay in surgery in small bowel obstruction. Am Surg. 2012, 78 (4): 403-407.

Fleshner PR, Siegman MG, Slater GI, Brolin RE, Chandler JC, Aufses AH: A prospective, randomized trial of short versus long tubes in adhesive small-bowel obstruction. Am J Surg. 1995, 170 (4): 366-370. 10.1016/S0002-9610(99)80305-5.

Sakakibara T, Harada A, Yaguchi T, Koike M, Fujiwara M, Kodera Y, Nakao A: The indicator for surgery in adhesive small bowel obstruction patient managed with long tube. Hepatogastroenterology. 2007, 54 (75): 787-790.

Moran BJ: Adhesion-related small bowel obstruction. Colorectal Dis. 2007, 9 (Suppl 2): 39-44.

Fevang BT, Jensen D, Svanes K, Viste A: Early operation or conservative management of patients with small bowel obstruction?. Eur J Surg. 2002, 168 (8–9): 475-481.

Abbas S, Bissett IP, Parry BR: Oral water soluble contrast for the management of adhesive small bowel obstruction. Cochrane Database Syst Rev. 2007, 18 (3): CD004651.

Branco BC, Barmparas G, Schnüriger B, Inaba K, Chan LS, Demetriades D: Systematic review and meta-analysis of the diagnostic and therapeutic role of water-soluble contrast agent in adhesive small bowel obstruction. Br J Surg. 2010, 97 (4): 470-478. 10.1002/bjs.7019.

Landercasper J, Cogbill TH, Merry WH, Stolee RT, Strutt PJ: Long-term outcome after hospitalization for small-bowel obstruction. Arch Surg. 1993, 128: 765-770. 10.1001/archsurg.1993.01420190059008.

Schraufnagel D, Rajaee S, Millham FH: How many sunsets?Timing of surgery in adhesive small bowel obstruction: A study of the Nationwide Inpatient Sample. J Trauma Acute Care Surg. 2013, 74 (1): 181-187. 10.1097/TA.0b013e31827891a1. doi:10.1097/TA.0b013e31827891a1 . discussion 187–9

Diaz JJ, Bokhari F, Mowery NT, Acosta JA, Block EF, Bromberg WJ, Collier BR, Cullinane DC, Dwyer KM, Griffen MM, Mayberry JC, Jerome R: Guidelines for management of small bowel obstruction. J Trauma. 2008, 64 (6): 1651-1664. 10.1097/TA.0b013e31816f709e.

Guo S-B, Duan Z-J: Decompression of the small bowel by endoscopic long-tube placement. World J Gastroenterol. 2012, 18 (15): 1822-1826. 10.3748/wjg.v18.i15.1822. doi:10.3748/wjg.v18.i15.1822

Assalia A, Kopelman D, Bahous H, Klein Y, Hashmonai M: Gastrografin for mechanical partial, small bowel obstruction due to adhesions. Harefuah. 1997, 132 (9): 629-633.

Choi HK, Law WL, Ho JW, Chu KW: Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective evaluation. World J Gastroenterol. 2005, 11 (24): 3742-3745.

Burge J, Abbas SM, Roadley G, Donald J, Connolly A, Bissett IP, Hill AG: Randomized controlled trial of Gastrografin in adhesive small bowel obstruction. ANZ J Surg. 2005, 75 (8): 672-674. 10.1111/j.1445-2197.2005.03491.x.

Wadani HAI, Awad NIA, Hassan KA, Zakaria HM, Abdulmohsen Al Mulhim A, Alaqeel FO: Role of water soluble contrast agents in assigning patients to a Non-operative course in adhesive small bowel obstruction. Oman Medical Journal. 2011, 26 (6): 454-456. 10.5001/omj.2011.116. doi:10.5001/omj2011.116

Biondo S, Parés D, Mora L, Martí Ragué J, Kreisler E, Jaurrieta E: Randomized clinical study of Gastrografin administration in patients with adhesive small bowel obstruction. J Surg. 2003, 90 (5): 542-546.

Abbas SM, Bissett IP, Parry BR: Meta-analysis of oral water-soluble contrast agent in the management of adhesive small bowel obstruction. Br J Surg. 2007, 94 (4): 404-411. 10.1002/bjs.5775.

Chen SC, Yen ZS, Lee CC, Liu YP, Chen WJ, Lai HS, Lin FY, Chen WJ: Nonsurgical management of partial adhesive small-bowel obstruction with oral therapy: a randomized controlled trial. CMAJ. 2005, 173 (10): 1165-1169. 10.1503/cmaj.1041315.

Ambiru S, Furuyama N, Kimura F, Shimizu H, Yoshidome H, Miyazaki M, Ochiai T: Effect of hyperbaric oxygen therapy on patients with adhesive intestinal obstruction associated with abdominal surgery who have failed to respond to more than 7 days of conservative treatment. Hepatogastroenterology. 2008, 55 (82–83): 491-495.

Cox MR, Gunn IF, Eastman MC, Hunt RF, Heinz AW: The safety and duration of non-operative treatment for adhesive small bowel obstruction. Aust N Z J Surg. 1993, 63 (5): 367-371. 10.1111/j.1445-2197.1993.tb00404.x.

Shou-Chuan S, Kuo-Shyang J, Lin S-C: Adhesive small bowel obstruction: How long can patients tolerate conservative treatment?. World J Gastroenterol. 2003, 9 (3): 603-605.

Duron JJ, Silva NJ, du Montcel ST, Berger A, Muscari F, Hennet H, Veyrieres M, Hay JM: Adhesive postoperative small bowel obstruction: incidence and risk factors of recurrence after surgical treatment: a multicenter prospective study. Ann Surg. 2006, 244 (5): 750-757. 10.1097/01.sla.0000225097.60142.68.

Scott-Coombes DM, Vipond MN, Thompson JM: General surgeons attitudes to the treatment and prevention of abdominal adhesions. Ann R Coll Surg Engl. 1993, 75: 123-128.

Levrant SG, Bieber E, Barnes R: Risk of anterior abdominal wall adhesions increases with number and type of previous laparotomy. J Am Assoc Gynecol Laparosc. 1994, 1 (4): S19-

Van Der Krabben AA, Dijkstra FR, Nieuwenhuijzen M: Morbidity and mortality of inadvertent enterotomy during adhesiolysis. Br J Surg. 2000, 87: 467-471. 10.1046/j.1365-2168.2000.01394.x.

Tittel A, Treutner KH, Titkova S: Comparison of adhesion reformation after laparoscopic and conventional adhesiolysis in an animal model. Langenbeck's Arch Surg. 2001, 386: 141-145. 10.1007/s004230000190.

Tolutope O, Scott W: Helton. Survey opinions on operative management of adhesive small bowel obstruction: laparoscopy versus laparotomy in the state of Connecticut. Surg Endosc. 2011, 25: 2516-2521. 10.1007/s00464-011-1579-3.

Gamal EM, Metzger P, Szabo G: The influence of intraoperative complications on adhesion formation during laparoscopic and conventional cholecystectomy in an animal model. Surg Endosc. 2001, 15: 873-877. 10.1007/s004640000358.

Gadallah MF, Torres-Rivera C, Ramdeen G, Myrick S, Habashi S, Andrews G: Relationship between intraperitoneal bleeding, adhesions, and peritoneal dialysis catheter failure: a method of prevention. Adv Perit Dial. 2001, 17: 127-129.

Agresta F, Ansaloni L, Baiocchi GL, Bergamini C, Campanile FC, Carlucci M, Cocorullo G, Corradi A, Franzato B, Lupo M, Mandalà V, Mirabella A, Pernazza G, Piccoli M, Staudacher C, Vettoretto N, Zago M, Lettieri E, Levati A, Pietrini D, Scaglione M, De Masi S, De Placido G, Francucci M, Rasi M, Fingerhut A, Uranüs S, Garattini S: Laparoscopic approach to acute abdomen from the Consensus Development Conference of the Società Italiana di Chirurgia Endoscopica e nuove tecnologie (SICE), Associazione Chirurghi Ospedalieri Italiani (ACOI), Società Italiana di Chirurgia (SIC), Società Italiana di Chirurgia d'Urgenza e del Trauma (SICUT), Società Italiana di Chirurgia nell'Ospedalità Privata (SICOP), and the European Association for Endoscopic Surgery (EAES). Surg Endosc. 2012, 26 (8): 2134-2164. 10.1007/s00464-012-2331-3. doi:10.1007/s00464-012-2331-3

Nagle A, Ujiki M, Denham W, Murayama K: Laparoscopic adhesiolysis for small bowel obstruction. Am J Surg. 2004, 187 (4): 464-470. 10.1016/j.amjsurg.2003.12.036.

Szomstein S, Lo Menzo E, Simpfendorfer C:Laparoscopic lysis of adhesions. World J Surg. 2006, 30: 535-540. 10.1007/s00268-005-7778-0.

Ming-Zhe L, Lei L, Long-bin X, Wen-hui W, Yu-long H, Xin-ming S: Laparoscopic versus open adhesiolysis in patients with adhesive small bowel obstruction: a systematic review and meta-analysis. Am J Surg. 2012, 204 (5):

Stephanian SA, Apoian VT, Abramian RA, Drampian AF, Eiramdhzian KT: Laparoscopic adhesiolysis in the treatment of acute adhesive obstruction of the small intestine. Klin Khir. 2011, 7: 11-14.

Vettoretto N, Carrara A, Corradi A, De Vivo G, Lazzaro L, Ricciardelli L, Agresta F, Amodio C, Bergamini C, Catani M, Cavaliere D, Cirocchi R, Gemini S, Mirabella A, Palasciano N, Piazza D, Piccoli M, Rigamonti M, Scatizzi M, Tamborrino E, Zago M: Laparoscopic adhesiolysis: consensus conference guidelines. Colorectal diseases. The Association of Coloproctology of great Britain and Ireland. 2012, 14: e208-e2015. 10.1111/j.1463-1318.2012.02968.x.

Swank DJ, Swank-Bordewijk SC, Hop WC, van Erp WF, Janssen IM, Bonjer HJ, Jeekel J: Laparoscopic adhesiolysis in patients with chronic abdominal pain: a blinded randomised controlled multi-centre trial. Lancet. 2003, 361 (9365): 1247-1251. 10.1016/S0140-6736(03)12979-0.

Cirocchi R, Abraha I, Farinella E, Montedori A, Sciannameo F: Laparoscopic versus open surgery in small bowel obstruction. Cochrane Database Syst Rev. 2010, 17 (2): CD007511-Review

Grafen FC, Neuhaus V, Schöb O, Turina M: Management of acute small bowel obstruction from intestinal adhesions: indications for laparoscopic surgery in a community teaching hospital. Langenbecks Arch Surg. 2010, 395: 57-63.

Suter M, Zermatten P, Hakic N: Laparoscopic management of mechanical small bowel obstruction: are there predictors of success or failure?. Surg Endosc. 2000, 14: 478-484. 10.1007/s004640000104.

León EL, Metzger A, Tsiotos GG: Laparoscopic management of small bowel obstruction: indications and outcomes. J Gastrointest Surg. 1998, 2: 132-140. 10.1016/S1091-255X(98)80003-6.

Pekmezci S, Altinli E, Saribeyoglu K: Enteroclysis-guided laparoscopic adhesiolysis in recurrent adhesive small bowel obstructions. Surg Laparosc Endosc Percutan Tech. 2001, 12: 165-170.

O’Connor DB, Winter DC: The role of laparoscopy in the management of acute small bowel obstruction: a review of over 2000 cases. Surg Endosc. 2012, 26 (1): 12-17. 10.1007/s00464-011-1885-9. doi:10.1007/s00464-011-1885-9

Navez B, Arimont JM, Guit P: Laparoscopic approach in acute small bowel obstruction. A review of 68 patients. Hepatogastroenterology. 1998, 45: 2146-2150.

Van Goor H: Consequences and complications of peritoneal adhesions. Colorectal Dis. 2007, 9 (Suppl 2): 25-34.

Sato Y, Ido K, Kumagai M: Laparoscopic adhesiolysis for recurrent small bowel obstruction: long-term follow-up. Gastrointest Endosc. 2001, 54: 476-479. 10.1067/mge.2001.117760.

Chosidow D, Johanet H, Montario T: Laparoscopy for acute smallbowel obstruction secondary to adhesions. J Laparoendosc Adv Surg Tech. 2000, 10: 155-159. 10.1089/lap.2000.10.155.

Farinella E, Cirocchi R, La Mura F, Morelli U, Cattorini L, Delmonaco P, Migliaccio C, De Sol AA, Cozzaglio L: Sciannameo F Feasibility of laparoscopy for small bowel obstruction. World J Emerg Surg. 2009, 4: 3-10.1186/1749-7922-4-3.

Levard H, Boudet MJ, Msika S: Laparoscopic treatment of acute small bowel obstruction: a multicentre retrospective study. A N Z J Surg. 2001, 71: 641-646. 10.1046/j.0004-8682.2001.02222.x.

Wullstein C, Gross E: Laparoscopic compared with conventional treatment of acute adhesive small bowel obstruction. Br J Surg. 2003, 90: 1147-1151. 10.1002/bjs.4177.

Khaikin M, Schneidereit N, Cera S, Sands D, Efron J, Weiss G, Nogueras JJ, Vernava AM, Wexner SD: Laparoscopic vs. open surgery for acute adhesive small-bowel obstruction: patient’ outcome and costeffextiveness. Surg Endosc. 2007, 21: 742-746. 10.1007/s00464-007-9212-1.

Peschaud F, Alves A, Berdah S, Kianmanesh R, Lurent C, Ma Brut JY, Mariette C, Meurette G, Pirro N, Veryrie N, Slim K: Indicazioni alla laparoscopia in chirurgia generale e digestiva. J Chir. 2006, 6: 65-79.

Franklin ME, Gonzales JJ, Miter DB, Glass JL, Paulson D: Laparoscopic diagnosis and treatment of intestinal obstruction. Surg Endosc. 2004, 18: 26-30. 10.1007/s00464-003-8804-7.

Catena F, Di Saverio S, Ansaloni L: CHAPTER 7 Adhesive Small Bowel Obstruction. Updates in Surgery: The Role of Laparoscopy in Emergency Abdominal Surgery. Edited by: Mandalà V. 2012, Verlag Italia: Springer, 89-104. 10.1007/978-88-470-2327-7. ISBN 978-88-470-2326-0

Levard H, Boudet MJ, Msika S, Molkhou JM, Hay JM, Laborde Y: French association for surgical research. Laparoscopic treatment of acute small bowel obstruction: a multicentre retrospective study. Aust N Z J Surg. 2001, 71: 641-646. 10.1046/j.0004-8682.2001.02222.x.

Duh QY: Small bowel obstruction. Endosurgery. Edited by: Toouli J, Gossot D, Hunter JG. 1998, New York: Churchill Livingstone, 425-431.

Di Saverio S, Vettoretto N, Catena F, Italian Working Group on Peritoneal Adhesions and Asbo Management: Elasbo study: emergency laparoscopy for relief of adhesive small-bowel obstruction: indications, technique, and results in 103 cases from a multicenter study of the WSES. Clin Congr Am Coll Surg, Oral Free paper Sess Gen Surg. ISP062013

Schnüriger B, Barmparas G, Branco BC, Lustenberger T, Inaba K, Demetriades D: Prevention of Postoperative peritoneal adhesions: a review of the literature. Am J Surg. 201 (1): 111-121.

Fevang BT, Fevang J, Lie SA, Søreide O, Svanes K, Viste A: Long-term prognosis after operation for adhesive small bowel obstruction. Ann Surg. 2004, 240 (2): 193-201. 10.1097/01.sla.0000132988.50122.de.

Soybir GR, Koksoy F, Polat C: The effects of sterile or infected bile and dropped gallstones in abdominal adhesions and abscess formation. Surg Endosc. 1997, 11: 711-713. 10.1007/s004649900433.

Van den Tol P, Haverlag R, van Rossen ME: Glove powder promotes adhesion formation and facilitates tumour cell adhesion and growth. Br J Surg. 2001, 88: 1258-1263. 10.1046/j.0007-1323.2001.01846.x.

Cooke A, Hamilton DG: The significance of starch powder contamination in the aetiology of peritoneal adhesions. Br J Surg. 1977, 64: 410-412. 10.1002/bjs.1800640610.

Barmparas G, Branco BC, Schnüriger B, Lam L, Inaba K, Demetriades D: The incidence and risk factors of post-laparotomy adhesive small bowel obstruction. J Gastrointest Surg. 2010, 14 (10): 1619-1628. 10.1007/s11605-010-1189-8.

Malvasi A, Tinelli A, Farine D: Effects of visceral peritoneal closure on scar formation at cesarean delivery. Int J Gynecol Obstet. 2009, 105: 131-135. 10.1016/j.ijgo.2008.12.019.

Adhesion Barrier Study Group: Prevention of postsurgical adhesions by INTERCEED(TC7), an absorbable adhesion barrier: a prospective randomized multicenter clinical study. INTERCEED(TC7). Fertil Steril. 1989, 51 (6): 933-938.

Saravelos H, Li TC: Post-operative adhesions after laparoscopic electrosurgical treatment for polycystic ovarian syndrome with the application of Interceed to one ovary: a prospective randomized controlled study. Hum Reprod. 1996, 11 (5): 992-997. 10.1093/oxfordjournals.humrep.a019337.

Azziz R, Adhesion Barrier Study Group: Microsurgery alone or with INTERCEED absorbable adhesion barrier for pelvic sidewall adhesion re-formation: The INTERCEED (TC7). II. Surg Gynecol Obstet. 1993, 177: 135-139.

Nordic Adhesion Prevention Study Group: The efficacy of Interceed (TC7)* for prevention of reformation of postoperative adhesions on ovaries, fallopian tubes, and fimbriae in microsurgical operations for fertility: a multicenter study. Fertil Steril. 1995, 63: 709-714.

Wiseman DM, Trout JR, Franklin RR: Metaanalysis of the safety and efficacy of an adhesion barrier (Interceed TC7) in laparotomy. J Reprod Med. 1999, 44: 325-331.

Ahmad G, Duffy JM, Farquhar C: Barrier agents for adhesion prevention after gynaecological surgery. Cochrane Database Syst Rev. 2008, 16: CD000475-

Montz FJ, Monk BJ, Lacy SM: The gore-Tex surgical membrane: effectiveness as a barrier to inhibit postradical pelvic surgery adhesions in a porcine model. Gynecol Oncol. 1992, 45: 290-293. 10.1016/0090-8258(92)90306-4.

Beck DE, Cohen Z, Fleshman JW: A prospective, randomized, multicenter, controlled study of the safety of Seprafilm adhesion barrier in abdominopelvic surgery of the intestine. Dis Colon Rectum. 2003, 46: 1310-1319. 10.1007/s10350-004-6739-2.

Becker M, Dayton MT, Fazio VW: Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg. 1996, 183: 297-306.

Vrijland WW, Tseng LN, Eijkman HJ: Fewer intraperitoneal adhesions with use of hyaluronic acid-carboxymethylcellulose membrane: a randomized clinical trial. Ann Surg. 2002, 235: 193-199. 10.1097/00000658-200202000-00006.

Cohen Z, Senagore AJ, Dayton MT: Prevention of postoperative abdominal adhesions by a novel, glycerol/sodium hyaluronate/carboxymethylcellulose-based bioresorbable membrane: a prospective, randomized, evaluator-blinded multicenter study. Dis Colon Rectum. 2005, 48: 1130-1139. 10.1007/s10350-004-0954-8.

Kumar S, Wong PF, Leaper DJ: Intra-peritoneal prophylactic agents for preventing adhesions and adhesive intestinal obstruction after nongynaecological abdominal surgery. Cochrane Database Syst Rev. 2009, 1: CD005080-

Fazio VW, Cohen Z, Fleshman JW: Reduction in adhesive smallbowel obstruction by Seprafilm adhesion barrier after intestinal resection. Dis Colon Rectum. 2006, 49: 1-11. 10.1007/s10350-005-0268-5.

Kudo FA, Nishibe T, Miyazaki K: Use of bioresorbable membrane to prevent postoperative small bowel obstruction in transabdominal aortic aneurysm surgery. Surg Today. 2004, 34: 648-651.

Zeng Q, Yu Z, You J, Zhang Q: Efficacy and safety of Seprafilm for preventing postoperative abdominal adhesion: systematic review and meta-analysis. World J Surg. 2007, 31 (11): 2125-2131. 10.1007/s00268-007-9242-9.

Catena F, Ansaloni L, Di Saverio S, Pinna AD, P.O.P.A. Study: Prevention of postoperative abdominal adhesions by icodextrin 4% solution after laparotomy for adhesive small bowel obstruction. A prospective randomized controlled trial. J Gastrointest Surg. 2012, 16: 382-388. 10.1007/s11605-011-1736-y.

Johns DA, Ferland R, Dunn R: Initial feasibility study of a sprayable hydrogel adhesion barrier system in patients undergoing laparoscopic ovarian surgery. J Am Assoc Gynecol Laparosc. 2003, 10: 334-338. 10.1016/S1074-3804(05)60257-5.

Tang CL, Jayne DG, Seow-Choen F: A randomized controlled trial of.5% ferric hyaluronate gel (Intergel) in the prevention of adhesions following abdominal surgery. Ann Surg. 2006, 243: 449-455. 10.1097/01.sla.0000207837.71831.a2.

Sparnon AL, Spitz L: Pharmacological manipulation of postoperative intestinal adhesions. Aust N Z J Surg. 1989, 59: 725-729. 10.1111/j.1445-2197.1989.tb01665.x.

Fang CC, Chou TH, Lin GS, Yen ZS, Lee CC, Chen SC: Peritoneal infusion with cold saline decreased postoperative intra-abdominal adhesion formation. World J Surg. 2010, 34 (4): 721-727. 10.1007/s00268-009-0378-7.

Coccolini F, Ansaloni L, Manfredi R, Campanati L, Poiasina E, Bertoli P, Capponi MG, Sartelli M, Di Saverio S, Cucchi M, Lazzareschi D, Pisano M, Catena F: Peritoneal adhesion index (PAI): proposal of a score for the “ignored iceberg” of medicine and surgery. World J Emerg Surg. 2013, 8 (1): 6-10.1186/1749-7922-8-6.