Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats

Food and Chemical Toxicology - Tập 43 Số 1 - Trang 57-63 - 2005
Fatma M. El‐Demerdash1, Mokhtar I. Yousef1, N.I. Abou El-Naga2
1Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163, Horreya Avenue, P.O. Box. 832, Alexandria 21526, Egypt
2Department of Home Economics, Faculty of Agriculture, Alexandria University, Alexandria, Egypt

Tóm tắt

Từ khóa


Tài liệu tham khảo

AOAC, 1990. Official Methods of Analysis of the Association of Official Analytical Agricultural Chemists, 13th ed. Benjamin, Franklin Station, Washington, DC

Almdal, 1988, Strict insulin treatment normalizes the organic nitrogen contents and the capacity of urea–N synthesis in experimental diabetes in rats, Diabetologica, 31, 114, 10.1007/BF00395558

Anwar, 2003, Oxidative stress in streptozotocin-induced diabetic rats: effects of garlic oil and melatonin, Comparative Biochemistry and Physiology, Part A: Molecular and Integrative Physiology, 135, 347, 10.1016/S1095-6433(03)00114-4

Augusti, 1996, Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.), Indian Journal of Experimental Biology, 34, 634

Augusti, 1996, Antiperoxide effect of S-allyl cysteine sulfoxide, a insulin secretagogue, in diabetic rats, Experientia, 52, 115, 10.1007/BF01923354

Babu, 1999, Renal lesions in streptozotocin-induced diabetic rats maintained on onion and capsaicin containing diets, Journal of Nutritional Biochemistry, 10, 477, 10.1016/S0955-2863(99)00031-5

Badr El-Din, 1997, Effect of panax ginsing extract on the nephrotoxicity of streptozotocin-induced experimental diabetes, Egyptian Journal Biochemistry, 15, 29

Banerjee, 2002, Effect of garlic on cardiovascular disorders: a review, Nutrition Journal, 1, 1

Baynes, 1999, Role of oxidative stress in diabetic complications, Diabetes, 48, 1, 10.2337/diabetes.48.1.1

Cabaud, 1958, Calorimetric measurement of lactate dehydrogenase activity of body fluids, Journal of Clinical Pathology, 30, 234, 10.1093/ajcp/30.3.234

Campos, 2003, Hypoglycaemic and antioxidant effects of onion, Allium cepa: dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats, International Journal of Food Science and Nutrition, 54, 241, 10.1080/09637480120092062

Dubey, 1994, Alloxan-induced diabetes in rabbits and effect of a herbal formulation D-400, Indian Journal of Pharmacology, 26, 225

Griffiths, 2002, Onions: a global benefit to health, Phytotherapy Research, 17, 603, 10.1002/ptr.1222

Habig, 1974, Glutathione S-transferases. The first enzymatic step in mercapturic acid formation, Journal of Biological Chemistry, 249, 7130, 10.1016/S0021-9258(19)42083-8

Henry, 1974

Jain, 1975, Garlic in alloxan-induced diabetic rabbits, American Journal of Clinical Nutrition, 28, 684, 10.1093/ajcn/28.7.684

Ji, 1992, The Three-dimensional structure of a glutathione S-transferase from the Mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-Å resolution, Biochemistry, 31, 10169, 10.1021/bi00157a004

Kumar, 1999, Reduced nociceptive responses in mice with alloxan induced hyperglycemia after garlic (Allium sativum) treatment, Indian Journal of Experimental Biology, 37, 662

Kumari, 2002, Antidiabetic and antioxidant effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa Linn) as compared to standard drugs in alloxan diabetic rats, Indian Journal of Experimental Biology, 40, 1005

Larcan, 1979, Light and electron microscopic study of hepatic lesions in the course of hyperlactatemia in diabetic patients, Diabetes Metabolism, 5, 103

Lowry, 1951, Protein measurement with the Folin Phenol Reagent, Journal of Biological Chemistry, 193, 269, 10.1016/S0021-9258(19)52451-6

Mansour, 2002, Biochemical study on the effects of some Egyptian herbs in alloxan-induced diabetic rats, Toxicology, 170, 221, 10.1016/S0300-483X(01)00555-8

Mathew, 1973, Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes l. Hypoglycaemic action and enhancement of serum insulin effect and glycogen synthesis, Indian Journal of Biochemistry and Biophysics, 10, 209

Moss, 1984, vol. 4, 92

Navarro, 1993, Free radicals scavenger and antihepatotoxic activity of Rosmarinus, Plant Medicine, 59, 312, 10.1055/s-2006-959688

Ohaeri, 2001, Effect of garlic oil on the levels of various enzyme in the serum and tissue of streptozotocin diabetic rats, Bioscience and Reproduction, 21, 19, 10.1023/A:1010425932561

Orekhov, 1997, Effects of garlic on atherosclerosis, Nutrition, 13, 656, 10.1016/S0899-9007(97)83010-9

Patton, 1977, Spectrophotometeric and kinetics investigation of the Berthelot reaction for determination of ammonia, Analytical Chemistry, 49, 464, 10.1021/ac50011a034

Pearlman, 1974, Detection and measurement of total bilirubin in serum, with use of surfactants as solubilizing agents, Clinical Chemistry, 20, 447, 10.1093/clinchem/20.4.447

Pedraza-Chaverri, 2000, Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes, Free Radicals in Biology and Medicine, 29, 602, 10.1016/S0891-5849(00)00354-3

Principato, 1985, Characterization of the soluble alkaline phosphatase from hepatopancreas of Squilla mantis L, Comparative Biochemistry and Physiology, 80B, 801

Rana, 1996, Protective effects of few antioxidants on liver function in rats treated with cadmium and mercury, Indian Journal of Experimental Biology, 34, 177

Reaven, 1983, Effect of age and diet on insulin secretion and insulin action in the rat, Diabetes, 32, 175, 10.2337/diabetes.32.2.175

Reitman, 1957, Colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases, American Journal of Clinical Pathology, 28, 56, 10.1093/ajcp/28.1.56

Sanchez, 1994, Hypoglycemic activity of Juniperus “Berries”, Plant Medicine, 60, 197, 10.1055/s-2006-959457

SAS, Statistical Analysis System., 1986. SAS User’s Guide: Statistics, Version 5 Edition. SAS Inst. Inc., Cary, NC, USA

Sheweita, 2002, Effect of some hypoglycemic herbs on the activity of phase I and II drug-metabolizing enzymes in alloxan-induced diabetic rats, Toxicology, 174, 131, 10.1016/S0300-483X(02)00048-3

Steel, 1981

Tappel, 1959, Inhibition of lipid peroxidation in mitochondria by vitamin E, Archives of Biochemistry and Biophysics., 80, 333, 10.1016/0003-9861(59)90259-0

Tjokroprawiro, 1983, Metabolic effects of onion and green beans on diabetic patients, Tohoku Journal of Experimental Medicine, 141, 671, 10.1620/tjem.141.Suppl_671

Trinder, 1969, Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor, Annals of Clinical Biochemistry, 6, 24, 10.1177/000456326900600108