Benefits of hormone replacement therapy in postmenopausal women

Wiley - Tập 19 Số 12 - Trang 635-641 - 2007
Richard Canderelli1, Lisa A. Leccesse1, Nancy L. Miller2, Janice Unruh Davidson1
1Memorial Regional Hospital, Hollywood, Florida
2College of Nursing and Health Sciences, Florida International University, Miami, Florida

Tóm tắt

AbstractPurpose: To provide an overview of current research regarding hormone replacement therapy (HRT) and to assist healthcare providers to better educate patients about potential benefits of this therapy.Data sources: A systematic review of healthcare literature was conducted with 602 articles selected from CINAHL, Medscape, Pubmed, and Medline databases. Keywords directing the search included hormone replacement therapy, benefits of hormone replacement therapy and trends, hormone replacement therapy and osteoporosis, hormone replacement, and menopause symptoms.Conclusions: According to the literature, HRT can assist women with postmenopausal symptoms. In addition, research shows that HRT can help some postmenopausal women with selected comorbid conditions such as osteoporosis, type II diabetes, certain cardiovascular pathologies, and colorectal cancer. The decision as to who should use any form of HRT needs to be based on the individual woman’s needs, quality of life, and potential risks versus benefits.Implications for practice: HRT has been a benefit to many women in the treatment of postmenopausal symptoms. Recent studies have shown that HRT, whether it is combined estrogen and progestin therapy, or estrogen‐only therapy, can help postmenopausal women with osteoporosis and some selected comorbid conditions. Recent research indicates that some women are dying from comorbid conditions rather than breast cancer. Although the research regarding HRT in some areas may be limited, further research adds to existing knowledge and offers new ideas and possibilities in the treatment of postmenopausal symptoms and selected comorbid conditions. Certainly HRT can improve quality of life and possibly longevity for selected women. Ongoing research is needed to further validate such benefits, as well as to further explore the risks and benefits of long‐term HRT. Increased knowledge about HRT will help healthcare providers better educate patients about the potential benefits of HRT, while providing documentation about who should take selected types of HRT or whether alternative treatment is preferred.

Từ khóa


Tài liệu tham khảo

American College of Obstetricians and Gynecologists. (2004).Frequently asked questions about hormone replacement therapy. Retrieved January 31 2007 fromhttp://acog.com/from_home/publications/press_releases/nr10‐01‐04.cfm

10.1001/jama.290.13.1739

Beers M. H. et al. (Eds.). (2005).Menopause. InThe Merck Manual of Geriatrics. Retrieved January 31 2007 fromhttp://www.merck.com/mrkshared/mmg/sec14/ch119/ch119a.jsp

10.1016/j.ajog.2003.09.045

10.1001/jama.290.13.1729

10.1056/NEJMoa032071

10.1067/mob.2003.201

10.2337/diacare.24.7.1144

10.1016/j.jmwh.2003.12.005

Hall L. (2000).Taking charge of menopause. Retrieved January 31 2007 fromhttp://www.fda.gov/fdac/features/1999/699_meno.html

10.1097/00007611-200209000-00001

10.1200/JCO.2003.05.151

10.1001/jama.289.24.3254

Michalowski J. &Nelson N. (2002).Summary of the evidence of the risks and benefits of postmenopausal use of hormones.Benchmark 2

(8) 2. Retrieved January 31 2007 fromhttp://www.cancer.gov/newscenter/benchmarks‐vol2‐issue8/page2

National Center for Complimentary and Alternative Medicine. (2005).Office of dietary supplements. Retrieved January 31 2007 fromhttp://od.nih.gov/factsheets/BlackCohosh

National Center for Health Statistics. (2006).Health United States 2006. Retrieved September 22 2007 fromhttp://nccam.nih.gov/health/blackcohosh

PRWEB. (2005).A possible link between $24‐billion‐a‐year “antacid” industry and the misery of menopause. Retrieved January 18 2007 fromhttp://www.emediawire.com/releases/2005/1/prweb196555.htm

10.1016/S0140-6736(02)11774-0

10.1001/jama.294.14.1765

10.1097/01.AOG.0000109428.87940.31

Thông tin
Thông tin xuất bản

Wiley

Tập 19 Số 12

635-641

Thông tin tác giả