Behavior of benzoins and hydroxy ketones in acid medium: II. Reactions of 1,2-bis(2,5-dimethyl-3-thienyl)-2-hydroxy-ethan-1-one with N,S-binucleophiles in trifluoroacetic acid

Pleiades Publishing Ltd - Tập 42 - Trang 860-864 - 2006
M. M. Krayushkin1, B. V. Lichitskii1, A. P. Mikhalev1, B. V. Nabatov1, A. A. Dudinov1, S. N. Ivanov1
1Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

Tóm tắt

1,2-Bis(2,5-dimethyl-3-thienyl)-2-hydroxyethan-1-one reacts with thioamides, thiosemicarbazides, and methyl hydrazinecarbodithioate in trifluoroacetic acid to give the corresponding thiazole, thiadiazine, and pyrazole derivatives, respectively.

Tài liệu tham khảo

Krayushkin, M.M., Lichitskii, B.V., Mikhalev, A.P., Dudinov, A.A., and Ivanov, S.N., Russ. J. Org. Chem., 2005, vol. 41, p. 87. Krayushkin, M.M., Ivanov, S.N., Martynkin, A.Yu., Lichitskii, B.V., Dudinov, A.A., and Uzhinov, B.M., Izv. Ross. Akad. Nauk, Ser. Khim., 2001, p. 113. Beyer, H., Bulka, E., and Beckhaus, F.-W., Chem. Ber., 1959, vol. 92, p. 2593. Irie, M., Chem. Rev., 2000, vol. 100, p. 1685. Krayushkin, M.M., Khim. Geterotsikl. Soedin., 2001, p. 19. Krayushkin, M.M., Ivanov, S.N., Martynkin, A.Yu., Lichitskii, B.V., Dudinov, A.A., and Uzhinov, B.M., Izv. Ross. Akad. Nauk, Ser. Khim., 2001, p. 2315.