Bcl-2 acts subsequent to and independent of Ca2+ fluxes to inhibit apoptosis in thapsigargin- and glucocorticoidmtreated mouse lymphoma cells

Cell Calcium - Tập 19 Số 6 - Trang 473-483 - 1996
Clark Distelhorst1, Thomas S. McCormick1
1Departments of Medicine and Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Tsujimoto, 1984, Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation, Science, 226, 1097, 10.1126/science.6093263

Bakshi, 1985, Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18, Cell, 41, 899, 10.1016/S0092-8674(85)80070-2

Cleary, 1986, Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation, Cell, 47, 19, 10.1016/0092-8674(86)90362-4

Chen-Levy, 1990, Membrane topology of the Bcl-2 proto-oncogenic protein demonstrated in vitro, J Biol Chem, 265, 4929, 10.1016/S0021-9258(19)34063-3

Hockenbery, 1990, Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death, Nature, 348, 334, 10.1038/348334a0

Chen-Levy, 1989, The bcl-2 candidate protooncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation, Mol Cell Biol, 9, 701, 10.1128/MCB.9.2.701

Alnemri, 1992, Overexpressed full-length human Bcl2 extends the survival of baculovirus-infected SO insect cells, 89, 7295

Monaghan, 1992, Ultrastructural localization of BCL-2 protein, J Histochem Cytochem, 40, 1819, 10.1177/40.12.1453000

Jacobson, 1993, Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA, Nature, 361, 365, 10.1038/361365a0

Krajewski, 1993, Investigation of the subcellular distribution of the bcl2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes, Cancer Res, 53, 4701

Oltvai, 1993, Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death, Cell, 75, 609, 10.1016/0092-8674(93)90509-O

Zamzami, 1995, Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death, J Exp Med, 182, 367, 10.1084/jem.182.2.367

Kane, 1993, Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species, Science, 262, 1274, 10.1126/science.8235659

Hockenbery, 1993, Bcl-2 functions in an antioxidant pathway to prevent apoptosis, Cell, 75, 241, 10.1016/0092-8674(93)80066-N

Muschel, 1995, Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling, Cancer Res, 55, 995

Shimizu, 1995, Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL, Nature, 374, 811, 10.1038/374811a0

Jacobson, 1995, Programmed cell death and Bcl-2 protection in very low oxygen, Nature, 374, 814, 10.1038/374814a0

Baffy, 1993, Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production, J Biol Chem, 268, 6511, 10.1016/S0021-9258(18)53280-4

Magnelli, 1994, Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts, Biochem Biophys Res Commun, 204, 84, 10.1006/bbrc.1994.2429

Lam, 1994, Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes, 91, 6569

Zhong, 1993, bcl-2 inhibits death of central neural cells induced by multiple agents, 90, 4533

Flomerfelt, 1994, Recessive mutations in a common pathway block thymocyte apoptosis induced by multiple signals, J Cell Biol, 127, 1729, 10.1083/jcb.127.6.1729

Duke, 1992, Morphological and biochemical assays of apoptosis, 3.17.1

Lam, 1993, Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells, Mol Endocrinol, 7, 686

Dubyak, 1986, Extracellular ATP activates polyphosphoinositide breakdown and Cal+ mobilization in Ehrlich ascites tumor cells, Arch Biochem Biophys, 245, 84, 10.1016/0003-9861(86)90192-X

Grynkiewicz, 1985, A new generation of Caz+ indicators with greatly improved fluorescence properties, J Biol Chem, 260, 3440, 10.1016/S0021-9258(19)83641-4

Putney, 1993, The signal for capacitative calcium entry, Cell, 75, 199, 10.1016/0092-8674(93)80061-I

Kao, 1994, Practical aspects of measuring [Ca2+]; with fluorescent indicators, Methods Cell Biol, 40, 155, 10.1016/S0091-679X(08)61114-0

Nicholson, 1978, Effect of glucocorticoid hormones in vitro on the structural integrity of nuclei in corticosteroidsensitive and -resistant lines of lymphosarcoma P1798, Cancer Res, 38, 3673

Nicholson, 1979, Independence of the lethal actions of glucocorticoids on lymphoid cells from possible hormone effects on calcium uptake, J Supramol Struct, 10, 165, 10.1002/jss.400100206

Alnemri, 1989, Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease, J Biol Chem, 264, 4104, 10.1016/S0021-9258(19)84968-2

Bansal, 1990, Dexamethasoneinduced killing of neoplastic cells of lymphoid derivation: lack of early calcium involvement, J Cell Physiol, 143, 105, 10.1002/jcp.1041430114

Kaiser, 1978, Further studies on the role of calcium in glucocorticoid-induced lymphocytolysis, Endocrinology, 103, 936, 10.1210/endo-103-3-936

Kaiser, 1977, Calcium dependence of glucocorticoidinduced lymphocytolysis, 74, 632

Cohen, 1984, Glucocorticoid activation of a calciumdependent endonuclease in thymocyte nuclei leads to cell death, J Immunol, 132, 38

Wyllie, 1984, Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis, J Pathol, 142, 67, 10.1002/path.1711420112

McConkey, 1989, Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration, Arch Biochem Biophys, 269, 365, 10.1016/0003-9861(89)90119-7

Ulatowski, 1993, Relationship between defective mouse mammary tumor virus envelope glycoprotein synthesis and GRP78 synthesis in glucocorticoid-treated mouse lymphoma cells: evidence for translational control of GRP78 synthesis, J Biol Chem, 268, 7482, 10.1016/S0021-9258(18)53200-2

Dowd, 1991, Evidence for early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid-mediated apoptosis, J Biol Chem, 266, 18423, 10.1016/S0021-9258(18)55076-6

Dowd, 1992, Stable expression of the calbindin-D28K complementary DNA interferes with the apoptotic pathway in lymphocytes, Mol Endocrinol, 6, 1843