Balancing selection in the extended MHC region maintains a subset of alleles with opposite risk profile for different autoimmune diseases

Genome Biology - 2010
Rachele Cagliani1, Stefania Riva1, Matteo Fumagalli2, Diego Forni1, Giacomo Pietro Comi3, Nereo Bresolin2, Mario Clerici4, Manuela Sironi1
1Scientific Institute IRCCS E.MEDEA, Bosisio Parini, Italy
2Scientific Institute IRCCS E. Medea, 23842, Bosisio Parini, LC, Italy
3Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, IRCCS Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena Foundation, Milan, Italy
4Chair of Immunology, Department of Biomedical Sciences and Technologies LITA Segrate, University of Milano, 20090, Milano, Italy

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