Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells.

Journal of Biological Chemistry - Tập 266 Số 26 - Trang 17707-17712 - 1991
Tamotsu Yoshimori1,2, Akira Yamamoto1,2, Yoshinori Moriyama1,2, Masamitsu Futai1,2, Yutaka Tashiro1,2
1 Department of Organic Chemistry and Biochemistry, Institute of Scientific and Industrial Research, Osaka Uniuersity, Ibaraki, Osaka 567, Japan
2From the Department of Physiology, Kansai Medical University, Fumizono-cho, Moriguchi, Osaka 570, Japan

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