BDNF–TrkB signaling and neuroprotection in schizophrenia
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Almeida, 2005, Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways, Cell Death and Differentiation, 12, 1329, 10.1038/sj.cdd.4401662
Angelucci, 2005, Effect of chronic olanzapine treatment on nerve growth factor and brain-derived neurotrophic factor in the rat brain, European Neuropsychopharmacology, 15, 311, 10.1016/j.euroneuro.2004.11.005
Angelucci, 2000, Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration, Journal of Neuroscience Research, 60, 783, 10.1002/1097-4547(20000615)60:6<783::AID-JNR11>3.0.CO;2-M
Arevalo, 2006, Neurotrophin signaling: many exciting surprises!, Cellular and Molecular Life Sciences, 63, 1523, 10.1007/s00018-006-6010-1
Bai, 2003, Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs, Journal of Neuroscience Research, 71, 127, 10.1002/jnr.10440
Bajestan, 2006, Association of AKT1 haplotype with the risk of schizophrenia in Iranian population, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 141, 383, 10.1002/ajmg.b.30291
Berger, 2003, Incipient neurovulnerability and neuroprotection in early psychosis, Psychopharmacology Bulletin, 37, 79
Biffo, 1995, Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development, Development, 121, 2461, 10.1242/dev.121.8.2461
Bird, 2002, DNA methylation patterns and epigenetic memory, Genes and Development, 16, 6, 10.1101/gad.947102
Buckley, 2007, Neurotrophins and schizophrenia, Schizophrenia Research, 94, 1, 10.1016/j.schres.2007.01.025
Buckley, 2007, Brain derived neurotropic factor in first-episode psychosis, Schizophrenia Research, 91, 1, 10.1016/j.schres.2006.12.026
Buckley, 2011, Brain-derived neurotrophic factor: findings in schizophrenia, Current Opinion in Psychiatry, 24, 122, 10.1097/YCO.0b013e3283436eb7
Chen da, 2009, Decreased levels of serum brain-derived neurotrophic factor in drug-naive first-episode schizophrenia: relationship to clinical phenotypes, Psychopharmacology, 207, 375, 10.1007/s00213-009-1665-6
Chen, 2007, Contextual learning induces an increase in the number of hippocampal CA1 neurons expressing high levels of BDNF, Neurobiology of Learning and Memory, 88, 409, 10.1016/j.nlm.2007.07.009
Chen, 2006, Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior, Science, 314, 140, 10.1126/science.1129663
Chen, 2004, Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons, Journal of Neuroscience, 24, 4401, 10.1523/JNEUROSCI.0348-04.2004
de Kloet, 2005, Stress and the brain: from adaptation to disease, Nature Reviews Neuroscience, 6, 463, 10.1038/nrn1683
Durany, 2001, Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses, Schizophrenia Research, 52, 79, 10.1016/S0920-9964(00)00084-0
Egan, 2003, The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function, Cell, 112, 257, 10.1016/S0092-8674(03)00035-7
Emamian, 2004, Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia, Nature Genetics, 36, 131, 10.1038/ng1296
Favalli, 2012, The role of BDNF in the pathophysiology and treatment of schizophrenia, Journal of Psychiatric Research, 46, 1, 10.1016/j.jpsychires.2011.09.022
Fumagalli, 2003, Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-d-aspartate receptor activity, Journal of Neuroscience Research, 72, 622, 10.1002/jnr.10609
Gama, 2007, Serum levels of brain-derived neurotrophic factor in patients with schizophrenia and bipolar disorder, Neuroscience Letters, 420, 45, 10.1016/j.neulet.2007.04.001
Gatt, 2009, Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety, Molecular Psychiatry, 14, 681, 10.1038/mp.2008.143
Gavin, 2011, Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis, Neuropsychopharmacology, 37, 531, 10.1038/npp.2011.221
Gonzalez-Pinto, 2010, Increase in brain-derived neurotrophic factor in first episode psychotic patients after treatment with atypical antipsychotics, International Clinical Psychopharmacology, 25, 241, 10.1097/YIC.0b013e328338bc5a
Green, 2011, Brain-derived neurotrophic factor levels in schizophrenia: a systematic review with meta-analysis, Molecular Psychiatry, 16, 960, 10.1038/mp.2010.88
Grillo, 2007, Reduced serum BDNF levels in schizophrenic patients on clozapine or typical antipsychotics, Journal of Psychiatric Research, 41, 31, 10.1016/j.jpsychires.2006.01.005
Hahn, 2006, Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia, Nature Medicine, 12, 824, 10.1038/nm1418
Hansen, 2004, Mechanisms leading to disseminated apoptosis following NMDA receptor blockade in the developing rat brain, Neurobiology of Disease, 16, 440, 10.1016/j.nbd.2004.03.013
Hashimoto, 2005, Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia, Journal of Neuroscience, 25, 372, 10.1523/JNEUROSCI.4035-04.2005
Hetman, 1999, Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase, Journal of Biological Chemistry, 274, 22569, 10.1074/jbc.274.32.22569
Hori, 2007, Effects of olanzapine on plasma levels of catecholamine metabolites, cytokines, and brain-derived neurotrophic factor in schizophrenic patients, International Clinical Psychopharmacology, 22, 21
Huang, 2001, Neurotrophins: roles in neuronal development and function, Annual Review of Neuroscience, 24, 677, 10.1146/annurev.neuro.24.1.677
Ikeda, 2004, Association of AKT1 with schizophrenia confirmed in a Japanese population, Biological Psychiatry, 56, 698, 10.1016/j.biopsych.2004.07.023
Ikeda, 2008, Low serum levels of brain-derived neurotrophic factor and epidermal growth factor in patients with chronic schizophrenia, Schizophrenia Research, 101, 58, 10.1016/j.schres.2008.01.017
Iritani, 2003, Immunohistochemical study of brain-derived neurotrophic factor and its receptor TrkB, in the hippocampal formation of schizophrenic brains, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 27, 801, 10.1016/S0278-5846(03)00112-X
Issa, 2010, An inverse relationship between cortisol and BDNF levels in schizophrenia: data from human postmortem and animal studies, Neurobiology of Disease, 39, 327, 10.1016/j.nbd.2010.04.017
Jarskog, 2000, Cortical bcl-2 protein expression and apoptotic regulation in schizophrenia, Biological Psychiatry, 48, 641, 10.1016/S0006-3223(00)00988-4
Jiang, 2005, The excitoprotective effect of N-methyl-d-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons, Journal of Neurochemistry, 94, 713, 10.1111/j.1471-4159.2005.03200.x
Jindal, 2010, Decreased BDNF in patients with antipsychotic naive first episode schizophrenia, Schizophrenia Research, 119, 47, 10.1016/j.schres.2009.12.035
Kim, 2010, Interaction between brain-derived neurotrophic factor Val66Met polymorphism and recent negative stressor in harm avoidance, Neuropsychobiology, 61, 19, 10.1159/000258639
Kuipers, 2006, Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: new insights and implications for therapy, Current Opinion in Drug Discovery and Development, 9, 580
Kutiyanawalla, 2011, Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment, PLoS ONE, 6, e26153, 10.1371/journal.pone.0026153
Lee, 2011, Reduced brain-derived neurotrophic factor serum concentrations in acute schizophrenic patients increase during antipsychotic treatment, Journal of Clinical Psychopharmacology, 31, 334, 10.1097/JCP.0b013e31821895c1
Lewin, 1996, Physiology of the neurotrophins, Annual Review of Neuroscience, 19, 289, 10.1146/annurev.ne.19.030196.001445
Lewis, 2000, Catching up on schizophrenia: natural history and neurobiology, Neuron, 28, 325, 10.1016/S0896-6273(00)00111-2
Lipska, 2001, BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs, European Journal of Neuroscience, 14, 135, 10.1046/j.1460-9568.2001.01633.x
Lu, 2008, Cell biology of BDNF and its relevance to schizophrenia, Novartis Foundation Symposium, 289, 119, 10.1002/9780470751251.ch10
Lubin, 2008, Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory, Journal of Neuroscience, 28, 10576, 10.1523/JNEUROSCI.1786-08.2008
Maisonpierre, 1990, NT-3 BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression, Neuron, 5, 501, 10.1016/0896-6273(90)90089-X
Maisonpierre, 1990, Neurotrophin-3: a neurotrophic factor related to NGF and BDNF, Science, 247, 1446, 10.1126/science.2321006
Martinowich, 2003, DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation, Science, 302, 890, 10.1126/science.1090842
Mill, 2008, Epigenomic profiling reveals DNA-methylation changes associated with major psychosis, American Journal of Human Genetics, 82, 696, 10.1016/j.ajhg.2008.01.008
Miranda, 2007, DNA methylation: the nuts and bolts of repression, Journal of Cellular Physiology, 213, 384, 10.1002/jcp.21224
Momose, 2002, Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms, Annals of Neurology, 51, 133, 10.1002/ana.10079
Murer, 2001, Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease, Progress in Neurobiology, 63, 71, 10.1016/S0301-0082(00)00014-9
Neves-Pereira, 2005, BDNF gene is a risk factor for schizophrenia in a Scottish population, Molecular Psychiatry, 10, 208, 10.1038/sj.mp.4001575
Neves-Pereira, 2002, The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study, American Journal of Human Genetics, 71, 651, 10.1086/342288
Palomino, 2006, Decreased levels of plasma BDNF in first-episode schizophrenia and bipolar disorder patients, Schizophrenia Research, 86, 321, 10.1016/j.schres.2006.05.028
Parikh, 2004, Olanzapine counteracts reduction of brain-derived neurotrophic factor and TrkB receptors in rat hippocampus produced by haloperidol, Neuroscience Letters, 356, 135, 10.1016/j.neulet.2003.10.079
Park, 2009, Differential effects of ziprasidone and haloperidol on immobilization stress-induced mRNA BDNF expression in the hippocampus and neocortex of rats, Journal of Psychiatric Research, 43, 274, 10.1016/j.jpsychires.2008.05.010
Park, 2006, Effects of quetiapine on the brain-derived neurotrophic factor expression in the hippocampus and neocortex of rats, Neuroscience Letters, 402, 25, 10.1016/j.neulet.2006.03.028
Pedrini, 2011, Serum brain-derived neurotrophic factor and clozapine daily dose in patients with schizophrenia: a positive correlation, Neuroscience Letters, 491, 207, 10.1016/j.neulet.2011.01.039
Pillai, 2008, Brain-derived neurotropic factor/TrkB signaling in the pathogenesis and novel pharmacotherapy of schizophrenia, Neuro-signals, 16, 183, 10.1159/000111562
Pillai, 2008, Erythropoietin prevents haloperidol treatment-induced neuronal apoptosis through regulation of BDNF, Neuropsychopharmacology, 33, 1942, 10.1038/sj.npp.1301566
Pillai, 2010, Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology, International Journal of Neuropsychopharmacology, 13, 535, 10.1017/S1461145709991015
Pillai, 2006, Differential effects of long-term treatment with typical and atypical antipsychotics on NGF and BDNF levels in rat striatum and hippocampus, Schizophrenia Research, 82, 95, 10.1016/j.schres.2005.11.021
Pillai, 2008, Cystamine prevents haloperidol-induced decrease of BDNF/TrkB signaling in mouse frontal cortex, Journal of Neurochemistry, 107, 941, 10.1111/j.1471-4159.2008.05665.x
Pirildar, 2004, Low serum levels of brain-derived neurotrophic factor in patients with schizophrenia do not elevate after antipsychotic treatment, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 28, 709, 10.1016/j.pnpbp.2004.05.008
Reis, 2008, Increased serum levels of brain-derived neurotrophic factor in chronic institutionalized patients with schizophrenia, Neuroscience Letters, 439, 157, 10.1016/j.neulet.2008.05.022
Rizos, 2010, Reduced serum BDNF levels in patients with chronic schizophrenic disorder in relapse, who were treated with typical or atypical antipsychotics, World Journal of Biological Psychiatry, 11, 251, 10.3109/15622970802182733
Rosa, 2006, The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 141B, 135, 10.1002/ajmg.b.30266
Roth, 2009, Epigenetic mechanisms in schizophrenia, Biochimica et Biophysica Acta, 1790, 869, 10.1016/j.bbagen.2009.06.009
Schabitz, 2000, Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia, Stroke, 31, 2212, 10.1161/01.STR.31.9.2212
Schlessinger, 2000, Cell signaling by receptor tyrosine kinases, Cell, 103, 211, 10.1016/S0092-8674(00)00114-8
Schwab, 2005, Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families, Biological Psychiatry, 58, 446, 10.1016/j.biopsych.2005.05.005
Sen, 2003, A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression, Neuropsychopharmacology, 28, 397, 10.1038/sj.npp.1300053
Sklar, 2002, Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus Brain-derived neutrophic factor, Molecular Psychiatry, 7, 579, 10.1038/sj.mp.4001058
Soontornniyomkij, 2011, Tyrosine kinase B protein expression is reduced in the cerebellum of patients with bipolar disorder, Journal of Affective Disorders, 133, 646, 10.1016/j.jad.2011.04.044
Szamosi, 2012, Hippocampal volume and the AKT signaling system in first-episode schizophrenia, Journal of Psychiatric Research, 46, 279, 10.1016/j.jpsychires.2011.12.005
Takahashi, 2000, Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients, Molecular Psychiatry, 5, 293, 10.1038/sj.mp.4000718
Tan, 2005, Decreased BDNF in serum of patients with chronic schizophrenia on long-term treatment with antipsychotics, Neuroscience Letters, 382, 27, 10.1016/j.neulet.2005.02.054
Terry, 2007, Time-dependent cognitive deficits associated with first and second generation antipsychotics: cholinergic dysregulation as a potential mechanism, Journal of Pharmacology and Experimental Therapeutics, 320, 961, 10.1124/jpet.106.106047
Thiselton, 2008, AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families, Biological Psychiatry, 63, 449, 10.1016/j.biopsych.2007.06.005
Thompson Ray, 2011, Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders, Journal of Psychiatry and Neuroscience, 36, 195, 10.1503/jpn.100048
Toyooka, 2002, Decreased levels of brain-derived neurotrophic factor in serum of chronic schizophrenic patients, Psychiatry Research, 110, 249, 10.1016/S0165-1781(02)00127-0
Ventriglia, 2002, Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease, Molecular Psychiatry, 7, 136, 10.1038/sj.mp.4000952
Vinogradov, 2009, Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia?, Biological Psychiatry, 66, 549, 10.1016/j.biopsych.2009.02.017
Weickert, 2003, Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia, Molecular Psychiatry, 8, 592, 10.1038/sj.mp.4001308
Weickert, 2005, Reductions in neurotrophin receptor mRNAs in the prefrontal cortex of patients with schizophrenia, Molecular Psychiatry, 10, 637, 10.1038/sj.mp.4001678
Wong, J., Rothmond, D.A., Webster, M.J., Shannon Weickert, C. Increases in two truncated TrkB isoforms in the prefrontal cortex of people with schizophrenia. Schizophrenia Bulletin, in press.
Wu, 1999, Neuroprotection with noninvasive neurotrophin delivery to the brain, Proceedings of the National Academy of Sciences of the United States of America, 96, 254, 10.1073/pnas.96.1.254
Xia, 2010, Brain-derived neurotrophic factor prevents phencyclidine-induced apoptosis in developing brain by parallel activation of both the ERK and PI-3K/Akt pathways, Neuropharmacology, 58, 330, 10.1016/j.neuropharm.2009.10.009
Xiu, 2009, Decreased serum BDNF levels in chronic institutionalized schizophrenia on long-term treatment with typical and atypical antipsychotics, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 33, 1508, 10.1016/j.pnpbp.2009.08.011
Xu, 2002, Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus, Neuroscience Letters, 321, 65, 10.1016/S0304-3940(02)00034-4
Yi, 2011, Lack of effect of brain derived neurotrophic factor (BDNF) Val66Met polymorphism on early onset schizophrenia in Chinese Han population, Brain Research, 1417, 146, 10.1016/j.brainres.2011.08.037
Yoshimura, 2007, Treatment with risperidone for 4 weeks increased plasma 3-methoxy-4-hydroxypnenylglycol (MHPG) levels, but did not alter plasma brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31, 1072, 10.1016/j.pnpbp.2007.03.010
Yoshimura, 2010, Different patterns of longitudinal changes in plasma levels of catecholamine metabolites and brain-derived neurotrophic factor after administration of atypical antipsychotics in first episode untreated schizophrenic patients, World Journal of Biological Psychiatry, 11, 256, 10.3109/15622970802309617
Yu, 2012, Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants, Journal of Neuroscience, 32, 4092, 10.1523/JNEUROSCI.5048-11.2012
Yuan, 2010, Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia, Journal of Affective Disorders, 124, 164, 10.1016/j.jad.2009.10.017
Zhang, 2012, Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls, Human Genetics, 131, 1187, 10.1007/s00439-012-1150-x
Zhang, 2008, BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia, Neuropsychopharmacology, 33, 2200, 10.1038/sj.npp.1301619