Autoimmune hematologic complications of umbilical cord blood transplantation

Gluckman, 1989, Hematopoietic reconstitution in a patient with Fanconi’s anemia by means of umbilical-cord blood from an HLA-identical sibling, N Engl J Med, 321, 1174, 10.1056/NEJM198910263211707 Hansen, 1980, Transplantation of marrow from an unrelated donor to a patient with acute leukemia, N Engl J Med, 303, 565, 10.1056/NEJM198009043031007 Henig, 2014, Hematopoietic stem cell transplantation-50 years of evolution and future perspectives, Rambam Maimonides Med J, 5, 10.5041/RMMJ.10162 Barker, 2010, Availability of cord blood extends allogeneic hematopoietic stem cell transplant access to racial and ethnic minorities, Biol Blood Marrow Transplant, 16, 1541, 10.1016/j.bbmt.2010.08.011 Feng, 2011, Clinical observation on the efficacy of umbilical blood stem cell transplantation in 30 cases with severe cerebral palsy, Chin J Blood Transfusion, 24, 602 Medhekar, 2016, Recent stem cell advances: cord blood and induced pluripotent stem cell for cardiac regeneration- a review, Int J Stem Cells, 9, 21, 10.15283/ijsc.2016.9.1.21 Ma, 2017, Exosomes derived from Akt-modified human umbilical cord mesenchymal stem cells improve cardiac regeneration and promote angiogenesis via activating platelet-derived growth factor D, Stem Cells Transl Med, 6, 51, 10.5966/sctm.2016-0038 Furfaro, 2007, Do adult stem cells ameliorate the damaged myocardium? Human cord blood as a potential source of stem cells, Curr Vasc Pharmacol, 5, 27, 10.2174/157016107779317170 Klein, 2001, T-Cell recovery in adults and children following umbilical cord blood transplantation, Biol Blood Marrow Transplant, 7, 454, 10.1016/S1083-8791(01)80013-6 Talvensaari, 2002, A broad T-cell repertoire diversity and an efficient thymic function indicate a favorable long-term immune reconstitution after cord blood stem cell transplantation, Blood, 99, 1458, 10.1182/blood.V99.4.1458 Thomson, 2000, Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation, Blood, 96, 2703, 10.1182/blood.V96.8.2703.h8002703_2703_2711 Niehues, 2001, Factors affecting lymphocyte subset reconstitution after either related or unrelated cord blood transplantation in children - a Eurocord analysis, Br J Haematol, 114, 42, 10.1046/j.1365-2141.2001.02900.x Beziat, 2009, Fully functional NK cells after unrelated cord blood transplantation, Leukemia, 23, 721, 10.1038/leu.2008.343 Brahmi, 2001, NK cells recover early and mediate cytotoxicity via perforin/granzyme and Fas/FasL pathways in umbilical cord blood recipients, Hum Immunol, 62, 782, 10.1016/S0198-8859(01)00275-0 Rutella, 2003, Identification of a novel subpopulation of human cord blood CD34-CD133-CD7-CD45+lineage- cells capable of lymphoid/NK cell differentiation after in vitro exposure to IL-15, J Immunol, 171, 2977, 10.4049/jimmunol.171.6.2977 Perez, 2003, A novel myeloid-like NK cell progenitor in human umbilical cord blood, Blood, 101, 3444, 10.1182/blood-2002-05-1501 Beaudette-Zlatanova, 2013, A potential role for B cells in suppressed immune responses in cord blood transplant recipients, Bone Marrow Transplant, 48, 85, 10.1038/bmt.2012.104 Daikeler, 2013, New autoimmune diseases after cord blood transplantation: a retrospective study of EUROCORD and the Autoimmune Disease Working Party of the European Group for Blood and Marrow Transplantation, Blood, 121, 1059, 10.1182/blood-2012-07-445965 Sanz, 2014, Autoimmune cytopenias after umbilical cord blood transplantation in adults with hematological malignancies: a single-center experience, Bone Marrow Transplant, 49, 1084, 10.1038/bmt.2014.107 Page, 2008, Posttransplant autoimmune hemolytic anemia and other autoimmune cytopenias are increased in very young infants undergoing unrelated donor umbilical cord blood transplantation, Biol Blood Marrow Transplant, 14, 1108, 10.1016/j.bbmt.2008.07.006 Holbro, 2012, Management of autoimmune diseases after haematopoietic stem cell transplantation, Br J Haematol, 3, 281, 10.1111/j.1365-2141.2012.09070.x Daikeler, 2011, Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party, Blood, 6, 1693, 10.1182/blood-2011-02-336156 Faraci, 2014, Autoimmune hematological diseases after allogeneic hematopoietic stem cell transplantation in children: an Italian multicenter experience, Biol Blood Marrow Transplant, 20, 272, 10.1016/j.bbmt.2013.11.014 Sanz, 2007, Autoimmune hemolytic anemia following allogeneic hematopoietic stem cell transplantation in adult patients, Bone Marrow Transplant, 39, 555, 10.1038/sj.bmt.1705641 Bhatt, 2016, Autoimmune hemolysis and immune thrombocytopenic purpura after cord blood transplantation may be life-threatening and warrants early therapy with rituximab, Bone Marrow Transplant, 51, 1579, 10.1038/bmt.2016.228 Szanto, 2020, Predictors for autoimmune cytopenias after allogeneic hematopoietic cell transplantation in children, Biol Blood Marrow Transplant, 26, 114, 10.1016/j.bbmt.2019.07.022 Godder, 1997, De novo chronic graft-versus-host disease presenting as hemolytic anemia following partially mismatched related donor bone marrow transplant, Bone Marrow Transplant, 19, 813, 10.1038/sj.bmt.1700746 Mackall, 1995, Age, thymopoiesis, and CD41 T-lymphocyte regeneration after intensive chemotherapy, N Engl J Med, 332, 143, 10.1056/NEJM199501193320303 Parkman, 1997, Immunological reconstitution following bone marrow transplantation, Immunol Rev, 157, 73, 10.1111/j.1600-065X.1997.tb00975.x Sherer, 1998, Autoimmune diseases and autoimmunity post-bone marrow transplantation, Bone Marrow Transplant, 22, 873, 10.1038/sj.bmt.1701437 Kuzmina, 2015, Clinical significance of autoantibodies in a large cohort of patients with chronic graft-versus-host disease defined by NIH criteria, Am J Hematol, 90, 114, 10.1002/ajh.23885 Sarantopoulos, 2015, B cells in chronic graftversus-host disease, Biol Blood Marrow Transplant, 21, 16, 10.1016/j.bbmt.2014.10.029 Srinivasan, 2012, Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans, Blood, 119, 1570, 10.1182/blood-2011-07-364414 Neunert, 2019, Pediatr Blood Cancer, 66, e27569, 10.1002/pbc.27569 O'Brien, 2004, Autoimmune haemolytic anaemia complicating haematopoietic cell transplantation in paediatric patients: high incidence and significant mortality in unrelated donor transplants for non-malignant diseases, Br J Haematol, 127, 67, 10.1111/j.1365-2141.2004.05138.x Cwynarski, 2001, Immune haemolytic anaemia following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukaemia: association with leukaemic relapse and treatment with donor lymphocyte infusions, Bone Marrow Transplant, 28, 581, 10.1038/sj.bmt.1703206 Sevilla, 2001, Acute autoimmune hemolytic anemia following unrelated cord blood transplantation as an early manifestation of chronic graft-versus-host disease, Bone Marrow Transplant, 28, 89, 10.1038/sj.bmt.1703087 Waespe, 2014, Treatment-refractory multi-lineage autoimmune cytopenia after unrelated cord blood transplantation: remission after combined bortezomib and vincristine treatment, Pediatr Blood Cancer, 61, 2112, 10.1002/pbc.25122 George, 2009, Definition, diagnosis and treatment of immune thrombocytopenic purpura, Haematologica, 94, 759, 10.3324/haematol.2009.007674 Newton, 2011, Fatigue in adult patients with primary immune thrombocytopenia, Eur J Haematol, 86, 420, 10.1111/j.1600-0609.2011.01587.x Arnold, 2007, Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura, Ann Intern Med, 146, 25, 10.7326/0003-4819-146-1-200701020-00006 Jillella, 2000, Autoimmune thrombocytopenia following autologous hematopoietic cell transplantation: review of literature and treatment options, Bone Marrow Transplant, 26, 925, 10.1038/sj.bmt.1702658 Deng, 2004, Immune thrombocytopenia purpura after HLA-haploidentical hematopoietic stem cell transplantation: a case report, Chin J Hematol, 25, 481 Ratanatharathorn, 2000, Anti-CD20 chimeric monoclonal antibody treatment of refractory immune-mediated thrombocytopenia in a patient with chronic graft-versus-host disease, Ann Intern Med, 133, 275, 10.7326/0003-4819-133-4-200008150-00011 Moran, 2012, Proteasome inhibitors as immunosuppressants: Biological rationale and clinical experience, Semin Hematol, 49, 270, 10.1053/j.seminhematol.2012.04.004 Ahn, 1974, Vincristine therapy of idiopathic and secondary thrombocytopenias, N Engl J Med, 291, 376, 10.1056/NEJM197408222910802 Schuetz, 2018, Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation, Blood Adv, 2, 2550, 10.1182/bloodadvances.2018020883 He, 2016, Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus, Nat Med, 22, 991, 10.1038/nm.4148 Zhang, 2018, Therapeutic potential of low-dose IL-2 in immune thrombocytopenia: an analysis of 3 cases, Cytometry B Clin Cytom, 94, 428, 10.1002/cyto.b.21601 Zhao, 2018, Fine tuning subsets of CD4, Int Immunopharmacol, 56, 269, 10.1016/j.intimp.2018.01.042 Klatzmann, 2015, The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases, Nat Rev Immunol, 15, 283, 10.1038/nri3823 Chao, 2008, Successful treatment of refractory immune hemolysis following unrelated cord blood transplant with Campath-1H., Pediatr Blood Cancer, 50, 917, 10.1002/pbc.21187 Rovira, 2013, Fatal immune hemolytic anemia following allogeneic stem cell transplantation: report of 2 cases and review of literature, Transfus Med Rev, 27, 166, 10.1016/j.tmrv.2013.02.004