Autoantibodies neutralizing thrombopoietin in a patient with a megakaryocytic thrombocytopenic purpura

Korn, D 1962. Congenital hypoplastic thrombocytopenia. Am J Clin Pathol.37:405-413

Hoffman, R 1991. Acquired pure amegakaryocytic thrombocytopenic purpura. Semin Hematol.28:303-312

Kaushansky, K 1995. Thrombopoietin: the primary regulator of platelet production. Blood.86:419-431

Casadevall, N, Dupuy, E, Molho-Sabatier, P, Tobelem, G, Varet, B, and Mayeux, P 1996. Autoantibodies against erythropoietin in a patient with pure red-cell aplasia. N Engl J Med.334:630-633

Hill, W, and Landgraf, R 1985. Successful treatment of amegakaryocytic thrombocytopenic purpura with cyclosporine. N Engl J Med.312:1060-1061

Mukai, HY, Kojima, H, and Todokoro, K et al. 1996. Serum thrombopoietin (TPO) levels in patients with amegakaryocytic thrombocytopenia are much higher than those with immune thrombocytopenic purpura. Thromb Haemost.76:675-678

Tahara, T, Usuki, K, and Sato, H et al. 1996. A sensitive sandwich ELISA for measuring thrombopoietin in human serum: serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders. Br J Haematol.93:783-788

Hagiwara, T, Kodama, I, Horie, K, Kato, T, and Miyazaki, H 1998. Proliferative properties of human umbilical cord blood megakaryocyte progenitor cells to human thrombopoietin. Exp Hematol.26:228-235