At the crossroads: AMP-activated kinase and the LKB1 tumor suppressor link cell proliferation to metabolic regulation

John M Kyriakis1
1Molecular Cardiology Research Institute, Tufts-New England Medical Center, Boston, USA

Tóm tắt

The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation.

Từ khóa


Tài liệu tham khảo

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