Association Among Lower Urinary Tract Symptoms, Erectile Function, and Sexual Satisfaction: Results from the Brazil LUTS Study

Sexual Medicine - Tập 8 - Trang 45-56 - 2020
Cristiano Mendes Gomes1, Marcio Augusto Averbeck2, Mitti Koyama3, Roberto Soler4
1Associate Professor of Urology, University of São Paulo School of Medicine, São Paulo, Brazil
2Head of Neuro-Urology, Department of Urology, Moinhos de Vento Hospital, Video-Urodynamics Unit, Porto Alegre, Brazil
3Kamiyama Statistical Consulting, São Paulo, Brazil
4Senior Medical Manager, Department of Medical Affairs – Oncology, Astellas Pharma Brazil, São Paulo, Brazil

Tóm tắt

Abstract Introduction Lower urinary tract symptoms (LUTS) affect ≥60% of adult men and are associated with erectile dysfunction (ED) and sexual dissatisfaction. Aim The aim of this study was to evaluate the relationship among male LUTS, ED, and sexual satisfaction. Methods This was a secondary analysis of the Brazil LUTS study, a cross-sectional, epidemiological survey conducted by telephone interview in 5 cities in Brazil. This analysis included men aged ≥40 years. Main Outcome Measure LUTS were identified using International Continence Society definitions. LUTS severity was assessed using the International Prostate Symptom Score questionnaire. Erectile function was assessed using the International Index of Erectile Function-5 (IIEF-5) questionnaire and sexual satisfaction was rated on a 5-point scale. Results 2,433 men participated in the study. Of 2,183 men reporting data on LUTS, 873 (40%) had LUTS “about half the time” or more. The prevalence of ED and sexual dissatisfaction was 14.4% and 7.8%, respectively. The proportion of men reporting ED and sexual dissatisfaction was higher among men with LUTS (24.6% and 13.8%, respectively) than men without LUTS (8.7% and 4.5%, respectively; P < .001). LUTS severity was negatively correlated with IIEF-5 scores (r = –0.199; P < .001); we estimated a 0.431-point decrease in IIEF-5 score per 3-point increase in International Prostate Symptom Score. Increased age and the presence of LUTS were associated with a greater chance of ED and sexual dissatisfaction; depression/anxiety and diabetes were associated with a greater chance of sexual dissatisfaction only. Among men with LUTS, urgency with fear of leaking, urgency urinary incontinence, and nocturnal enuresis were associated with a greater chance of ED, whereas slow stream and urgency urinary incontinence were associated with a greater chance of sexual dissatisfaction. Conclusion These results demonstrate that the presence of LUTS is associated with an increased chance of ED and sexual dissatisfaction in Brazilian men and reinforce the importance of a comprehensive assessment of these conditions.

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Sexual Medicine

Tập 8

45-56

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