Antioxidant treatment for impaired hypoxic ventilatory responses in experimental diabetes in the rat

Alireza, 2013, Effects of vitamin E on pathological changes induced by diabetes in rat lungs, Respir. Physiol. Neurobiol., 185, 593, 10.1016/j.resp.2012.11.017 Barreto, 2008, Characterization and quantitation of polyphenolic compounds in bark, kernel, leaves, and peel of mango (Mangifera indica L.), J. Agric. Food Chem., 56, 5599, 10.1021/jf800738r Bartels, 2013, Hypoxia and inflammation are two sides of the same coin, Proc. Natl. Acad. Sci. U. S. A., 110, 18351, 10.1073/pnas.1318345110 Bonfigli, 2006, High levels of antioxidant enzymatic defence assure good protection against hypoxic stress in spontaneously diabetic rats, Int. J. Biochem. Cell Biol., 38, 2196, 10.1016/j.biocel.2006.06.011 Carreau, 2011, Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia, J. Cell Mol. Med., 15, 1239, 10.1111/j.1582-4934.2011.01258.x Chu, 2014, Antagonism by bioactive polyphenols against inflammation: a systematic review, Inflammation Allergy Drug Targets, 13, 34, 10.2174/1871528112666131119211002 Daudu, 2002, Extra- and intracellular free iron and the carotid body responses, Respir. Physiol. Neurobiol., 130, 21, 10.1016/S0034-5687(01)00345-0 Dilshara, 2015, Mangiferin inhibits tumor necrosis factor–α–induced matrix metalloproteinase–9 expression and cellular invasion by suppressing nuclear factor–κB activity, BMB Rep., 48, 559, 10.5483/BMBRep.2015.48.10.003 Eleayu, 2013, Review of the mechanism of cell death resulting from streptozotocin challenge in experimental animals, its practical use and potential risk to humans, J. Diabetes Metab. Disord., 12, 60, 10.1186/2251-6581-12-60 Eltzschig, 2011, Hypoxia and inflammation, N. Engl. J. Med., 364, 656, 10.1056/NEJMra0910283 Ernster, 1992, The mode of action of lipid–soluble antioxidants in biological membranes: relationship between the effects of ubiquinol and vitamin E as inhibitors of lipid peroxidation in submitochondrial particles, Biofactors, 3, 241 Fraisl, 2009, Regulation of angiogenesis by oxygen and metabolism, Dev. Cell, 16, 167, 10.1016/j.devcel.2009.01.003 Furukawa, 2017, Increased oxidative stress in obesity and its impact on metabolic syndrome, J. Clin. Invest., 114, 1752, 10.1172/JCI21625 Hernandes, 2014, The role of Nox2–derived ROS in the development of cognitive impairment after sepsis, J. Neuroinflammation, 11, 36, 10.1186/1742-2094-11-36 Hisalkar, 2012, Evaluation of plasma superoxide dismutase and glutathione peroxidase in type 2 diabetic patients, Biol. Med., 4, 65 Ichiki, 1998, New antidiabetic compounds, mangiferin and its glucoside, Biol. Pharm. Bull., 21, 1389, 10.1248/bpb.21.1389 Kilkenny, 2010, Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research, PLoS Biol., 8, 10.1371/journal.pbio.1000412 Kim, 2007, Toll–like receptor–4 mediates vascular inflammation and insulin resistance in diet–induced obesity, Circ. Res., 100, 1589, 10.1161/CIRCRESAHA.106.142851 Kuhlicke, 2007, Hypoxia inducible factor (HIF)–1 coordinates induction of Toll–like receptors TLR2 and TLR6 during hypoxia, PLoS One, 2, 10.1371/journal.pone.0001364 López-Barneo, 2003, Oxygen and glucose sensing by carotid body glomus cells, Curr. Opin. Neurobiol., 13, 493, 10.1016/S0959-4388(03)00093-X Li, 2011, The role of manganese superoxide dismutase in inflammation defense, Enzyme Res., 2011, 10.4061/2011/387176 Liao, 2007, Hypoxia: a key regulator of angiogenesis in cancer, Cancer Metastasis Rev., 26, 281, 10.1007/s10555-007-9066-y Mahmoud, 2017, Nox2 contributes to hyperinsulinemia–induced redox imbalance and impaired vascular function, Redox Biol., 13, 288, 10.1016/j.redox.2017.06.001 Mekinova, 1995, Effect of intake of exogenous vitamins C, E and beta–carotene on the antioxidative status in kidneys of rats with streptozotocin–induced diabetes, Nahrung, 39, 257, 10.1002/food.19950390402 Miura, 2001, Antidiabetic activity of a xanthone compound, mangiferin, Phytomedicine, 8, 85, 10.1078/0944-7113-00009 Montserrat, 1985, Ventilatory control in diabetes mellitus, Eur. J. Respir. Dis., 67, 112 Muruganandan, 2005, Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats, J. Ethnopharmacol., 97, 497, 10.1016/j.jep.2004.12.010 Nanduri, 2009, Intermittent hypoxia degrades HIF–2α via calpains resulting in oxidative stress: implications for recurrent apnea–induced morbidities, Proc. Natl. Acad. Sci. U. S. A., 106, 1199, 10.1073/pnas.0811018106 Nishikawa, 2000, Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage, Nature, 404, 787, 10.1038/35008121 Ortega, 2013, Outcome of acute renal injury in diabetic mice with experimental endotoxemia: role of hypoxia inducible factor 1α, J. Diabetes Res., 2013, 10.1155/2013/254529 Pendyala, 2010, Redox regulation of Nox proteins, Respir. Physiol. Neurobiol., 174, 265, 10.1016/j.resp.2010.09.016 Pokorski, 2003, Ascorbic acid enhances hypoxic ventilatory reactivity in elderly subjects, J. Int. Med. Res., 31, 448, 10.1177/147323000303100514 Pokorski, 2015, Hypoxic ventilatory reactivity in experimental diabetes, Adv. Exp. Med. Biol., 860, 123, 10.1007/978-3-319-18440-1_14 Rauscher, 2001, Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin–induced diabetic rats, J. Biochem. Mol. Toxicol., 15, 41, 10.1002/1099-0461(2001)15:1<41::AID-JBT5>3.0.CO;2-Z Roy, 2004, Effects of iron–chelators on ion–channels and HIF–1 alpha in the carotid body, Respir. Physiol. Neurobiol., 141, 115, 10.1016/j.resp.2004.03.010 Sada, 2016, Hyperglycemia induces cellular hypoxia through production of mitochondrial ROS followed by suppression of aquaporin–1, PLoS One, 11, 10.1371/journal.pone.0158619 Saiki, 2005, The acute effects of insulin on the cardiorespiratory responses to hypoxia in streptozotocin–induced diabetic rats, Acta Physiol. Scand., 183, 107, 10.1111/j.1365-201X.2004.01375.x Sano, 1998, Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin–induced diabetes, Diabetologia, 41, 1355, 10.1007/s001250051076 Sato, 2011, Cellular hypoxia of pancreatic β–cells due to high levels of oxygen consumption for insulin secretion in vitro, J. Biol. Chem., 286, 12524, 10.1074/jbc.M110.194738 Semenza, 2012, The role of hypoxia-inducible factors in oxygen sensing by the carotid body, Adv. Exp. Med. Biol., 758, 1, 10.1007/978-94-007-4584-1_1 Shi, 2006, TLR4 links innate immunity and fatty acid-induced insulin resistance, J. Clin. Invest., 116, 3015, 10.1172/JCI28898 Takeda, 2016, Respiratory toxicity of dimethyl sulfoxide, Adv. Exp. Med. Biol., 885, 89, 10.1007/5584_2015_187 Tang, 2004, Characterizaton of antioxidant and antiglycation properties and isolation of active ingredients from traditional Chinese medicines, Free Radic. Biol. Med., 36, 1575, 10.1016/j.freeradbiomed.2004.03.017 Teppema, 2010, The ventilatory response to hypoxia in mammals: mechanisms, measurement, and analysis, Physiol. Rev., 90, 675, 10.1152/physrev.00012.2009 Wang, 2014, Pleiotropic actions of iron balance in diabetes mellitus, Rev. Endocr. Metab. Disord., 16, 15, 10.1007/s11154-014-9303-y Wang, 2014, Mangiferin and its aglycone norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase, Pharm. Biol., 52, 68, 10.3109/13880209.2013.814691 Weisbrod, 2005, Abnormal ventilatory responses to hypoxia in type 2 diabetes, Diabet. Med., 22, 563, 10.1111/j.1464-5491.2005.01458.x Xu, 1993, Postreceptor events involved in the up-regulation of beta-adrenergic receptor mediated lipolysis by testosterone in rat white adipocytes, Endocrinology, 132, 1651, 10.1210/endo.132.4.8384992 Yamazaki, 2002, Hypercapnic and hypoxic ventilatory responses in long-term streptozotocin-diabetic rats during conscious and pentobarbital-induced anesthetic states, Life Sci., 72, 10.1016/S0024-3205(02)02201-4 Ye, 2007, Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice, Am. J. Physiol. Endocrinol. Metab., 293, E1118, 10.1152/ajpendo.00435.2007 Ye, 2007, Role of insulin in the pathogenesis of free fatty acid-induced insulin resistance in skeletal muscle, Endocr. Metab. Immune Disord. Drug Targets, 7, 65, 10.2174/187153007780059423 Yin, 2009, Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue, Am. J. Physiol. Endocrinol. Metab., 296, E333, 10.1152/ajpendo.90760.2008 Zajac, 2013, Mangiferin and its traversal into the brain, Adv. Exp. Med. Biol., 756, 105, 10.1007/978-94-007-4549-0_14 Ziamajidi, 2017, Effects of garlic extract on TNF-α expression and oxidative stress status in the kidneys of rats with STZ + nicotinamide-induced diabetes, Pharm. Biol., 55, 526, 10.1080/13880209.2016.1255978