Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models

Jun Soo Bang1, Da Hee Oh1, Hyun Rim Choi1, Bongjun Sur2, Sung‐Jig Lim3, Jung Yeon Kim4, Haesik Yang5, Myung Chul Yoo6, Dae‐Hyun Hahm2, Kyoung Soo Kim1
1East-West Bone & Joint Research Institute, East-West Neo Medical Center, Kyung Hee University, 149 Sangil-dong, Gangdong-gu, Seoul, Republic of Korea
2Acupuncture and Meridian Science Research Center, Kyung Hee University, Hoeggidong, Dongdaemoon-gu, Seoul, Republic of Korea
3Department of Pathology, East-West Neo Meidcal Center, Kyung Hee University, 149 Sangil-dong, Gangdong-gu, Seoul, Republic of Korea
4Department of Pathology, Inje University Sanggye Paik Hospital, Sanggye 7 dong 761-7, Nowon-gu, Seoul, Republic of Korea
5Department of Internal Medicine, East-West Neo Medical Center, Kyung Hee University, 149 Sangil-dong, Gangdong-gu, Seoul, Republic of Korea
6Department of Orthopedic Surgery, East-West Neo Medical Center, Kyung Hee University, 149 Sangil-dong, Gangdong-gu, Seoul, Republic of Korea

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