Anti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase

Phytomedicine - Tập 7 Số 1 - Trang 21-24 - 2000
O.P. Gupta1, Seema Sing, Sarang Bani, Neha Sharma, S. Malhotra, B. K. Gupta, Sanjoy Banerjee, Sukhdev S. Handa
1Regional Research Laboratory (CSIR), Jammu Tawi, India

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Alarcon, 1992, Gastric anti-ulcer activity of Silymarin, a lipoxygenase inhibitor in rats, J. Pharm. Pharmacol., 44, 1931

Alarcon, 1992, Gastric anti-ulcer activity of Silymarin, a lipoxygenase inhibitor in rats, J. Pharm. Pharmacol., 44, 9

Antweiler, 1976, Effects of Silymarin on intoxication with ethionine and ethanol, 80

Baumann, 1980, Prostaglandin relation to their oxygen-scavenging properties, Arch. Pharm., 313, 330, 10.1002/ardp.19803130409

Braatz, 1976, Effects of Silybin on phalloidin pretreated mice, 44

Chen, 1990, Flavonoids as superoxide scavengers and antioxidents, Free Rad. Biol. Med., 9, 23

Gupta, 1992, A sensitive and relevant model for evaluating anti-inflammatory activity — papaya latex — induced rat paw inflammation, J. Pharmacol. Toxicol. Methods., 28, 15, 10.1016/1056-8719(92)90060-E

Hiroshi, 1984, Antihepatotoxic actions of flavonolignans from Silybum marianum fruits, Planta Med., 51, 248

Lonchampt, 1989, Protective effect of a purified flavonoid fraction against reactive oxygen radicals, Arzneim. Forsch., 39, 882

Newbould, 1963, Chemotherapy of arthritis induced in rats by mycobacterial adjuvant, Br. J. Pharmacol., 21, 127

Newbould, 1969, The pharmacology of Fenclozic acid 2- (4-Chloro- o -phenyl) theazol-4-y lactic acid: 1.C.1.54, 450, Myales: a new compound with anti-inflammatory, analgesic and antipyretic activity, Br. J. Pharmacol., 35, 487, 10.1111/j.1476-5381.1969.tb08290.x

Rauen, 1971, Die antihepatotoxische Wirkung von Silymarin bei experimentellen Leberschädigungen der Ratte durch Tetrachlorkohlenstoff, D-Galatosamin und Allylalkohol, Arzneim. Forsch., 21, 1194

Safayhi, 1992, Boswellic acids: novel, specific, nonredoxinhibitors of 5-lipoxygenase, J. Pharmacol. Exp. Ther., 261, 1143

Schriewer, 1973, Die antihepatotoxische Wirkung des Silymarins bei der Leberschädigung durch Thioacetamid, Arzneim-Forsch.,, 23, 160

Soroceanu, 1991

Tittel, 1978, Hochleistungsflüssigchromatographie von Silymarin II. Quantitative Bestimmung von Silymarin aus Silybum marianum durch Hochleistungsflüssigchromatographie, J. Chromatogr., 153, 227, 10.1016/S0021-9673(00)89876-3

Williams, 1973, Evaluation of prophylactic efficacy of Silymarin in CCL4-induced hepatoxicity, Res. Commun. Chem. Path Pharmacol., 6, 185

Winter, 1962, Carrageenan-induced edema in hind paw of rat as an assay for anti-inflammatory drugs, Proc. Soc. Biol. Med., 111, 544, 10.3181/00379727-111-27849

Young, 1989, 223