Angiotensin converting enzyme: Implications from molecular biology for its physiological functions

Bernstein, 1989, Mouse angiotensin-converting enzyme is a protein composed of two homologous domains, J. biol. Chem., 264, 11945, 10.1016/S0021-9258(18)80158-2

Bernstein, 1990, A deeply recessed active site in angiotensin converting enzyme is indicated from the binding characteristics of biotin-spacer-inhibitor reagents, Biochem. biophys. Res. Commun., 167, 310, 10.1016/0006-291X(90)91766-L

Bourne, 1989, Membrane peptidases in the pig choroid plexus and on other cell surfaces in contact with the cerebrospinal fluid, Biochem. J., 259, 69, 10.1042/bj2590069

Bull, 1985, Purification of angiotensin-converting enzyme from rabbit lung and human plasma by affinity chromatography, J. biol. Chem., 260, 2963, 10.1016/S0021-9258(18)89460-1

Bunning, 1985, The functional role of zinc in angiotensin converting enzyme: implications for the enzyme mechanism, J. inorg. Biochem., 24, 183, 10.1016/0162-0134(85)85002-9

Cohen, 1985, Synthetic and fermentation-derived angiotensin-converting enzyme inhibitors, A. Rev. Pharmac. Toxic., 25, 307, 10.1146/annurev.pa.25.040185.001515

Cumin, 1989, Evidence for a single active site in the human angiotensin I-converting enzyme from inhibitor binding studies with [3H]RU44 403: role of chloride, Biochem. biophys. Res. Commun., 163, 718, 10.1016/0006-291X(89)92282-1

Cushman, 1977, Design of potent competitive inhibitors of ACE. Carboxyalkanoyl and mercaptoalkanoyl ammo acids, Biochemistry, 16, 5484, 10.1021/bi00644a014

Das, 1975, Pulmonary angiotensinconverting enzyme. Structure and catalytic properties, J. biol. Chem., 250, 6762, 10.1016/S0021-9258(19)40997-6

Das, 1977, Serum angiotensin-converting enzyme. Isolation and relationship to the pulmonary enzyme, J. biol. Chem., 252, 1316, 10.1016/S0021-9258(17)40657-0

Edwards, 1985, Angiotensinconverting enzyme inhibitors: past, present and bright future, Lancet, i, 30, 10.1016/S0140-6736(85)90975-4

Ehlers, 1988, Catalysis of angiotensin I hydrolysis by human angiotensinconverting enzyme: effect of chloride and pH, Biochemistry, 27, 5538, 10.1021/bi00415a023

Ehlers, 1989, Angiotensinconverting enzyme: new concepts concerning its biological role, Biochemistry, 28, 5311, 10.1021/bi00439a001

Ehlers, 1989, Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial ACE, 86, 7741

El-Dorry, 1982, Molecular and catalytic properties of rabbit testicular dipeptidyl carboxypeptidase, J. biol. Chem., 257, 14,128, 10.1016/S0021-9258(19)45353-2

El-Dorry, 1983, Dipeptidyl carboxypeptidase from seminal fluid resembles the pulmonary rather than the testicular isoenzyme, Biochem. biophys. Res. Commun., 115, 1096, 10.1016/S0006-291X(83)80048-5

Erdos, 1985, Structure and functions of human angiotensin I-converting enzyme (kininase II), Biochem. Soc. Trans., 13, 42, 10.1042/bst0130042

Erdos, 1987, The angiotensin I-converting enzyme, Lab. Invest., 56, 345

Ferguson, 1988, Cell surface anchoring of proteins via glycosyl-phosphatidylinositol structures, A. Rev. Biochem., 57, 285, 10.1146/annurev.bi.57.070188.001441

Gavras, 1988, Angiotensin converting enzyme inhibitors. Properties and side effects, Hypertension, 11, 37

Hooper, 1987, Metabolism of neuropeptides by cell-surface peptidases

Hooper, 1985, Neurokinin B is hydrolysed by synaptic membranes and by endopeptidase-24.11 ('enkephalinase') but not by angiotensin converting enzyme, FEBS Lett., 190, 133, 10.1016/0014-5793(85)80443-9

Hooper, 1987, Isolation of two differentially glycosylated forms of peptidyl dipeptidase A (angiotensin converting enzyme) from pig brain: a re-evaluation of their role in neuropeptide metabolism, Biochem. J., 241, 625, 10.1042/bj2410625

Hooper, 1989, Characterization and isolation of the membrane anchor of angiotensin converting enzyme, Biochem. Soc. Trans., 17, 660, 10.1042/bst0170660

Hooper, 1985, The metabolism of neuropeptides, neurokinin A (substance K) is a substrate for endopeptidase-24.11 but not for peptidyl dipeptidase A (angiotensin converting enzyme), Biochem. J., 231, 357, 10.1042/bj2310357

Hooper, 1987, Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane, Biochem. J., 247, 85, 10.1042/bj2470085

Iwata, 1983, Rabbit pulmonary angiotensin-converting enzyme: the NH2-terminal fragment with enzymatic activity and its formation from the native enzyme by NH4OH treatment, Archs Biochem. Biophys., 227, 188, 10.1016/0003-9861(83)90362-4

Johnston, 1988, Angiotensin converting enzyme inhibitors—the balance sheet, Med. J. Aust., 148, 488, 10.5694/j.1326-5377.1988.tb99453.x

Jongeneel, 1989, A unique signature identifies a family of zinc-dependent metallopeptidases, FEBS Lett., 242, 211, 10.1016/0014-5793(89)80471-5

Kenny, 1991, Peptidases involved in the metabolism of bioactive peptides

Kenny, 1987, Cell surface peptidases, 169

Kumar, 1989, Structure of testicular angiotensinconverting enzyme. A segmental mosaic isozyme, J. biol. Chem., 264, 16,754, 10.1016/S0021-9258(19)84769-5

Lanzillo, 1977, Angiotensin I converting enzyme from human plasma, Biochemistry, 16, 5491, 10.1021/bi00644a015

Lanzillo, 1985, Angiotensin-converting enzyme from human tissues. Physicochemical, catalytic, and immunological properties, J. biol. Chem., 260, 14,938, 10.1016/S0021-9258(18)95683-8

Lattion, 1989, The testicular transcript of the angiotensin I-converting enzyme encodes for the ancestral, non-duplicated form of the enzyme, FEBS Lett., 252, 99, 10.1016/0014-5793(89)80897-X

Low, 1989, The glycosyl-phosphatidylinositol anchor of membrane proteins, Biochim. biophys. Acta, 988, 427, 10.1016/0304-4157(89)90014-2

Ondetti, 1988, Structural relationships of angiotensin converting enzyme inhibitors to pharmacologic activity, Circulation, 77, I-74

Ondetti, 1982, Enzymes of the renin-angiotensin system and their inhibitors, A. Rev. Biochem., 51, 283, 10.1146/annurev.bi.51.070182.001435

Pantoliano, 1984, Affinity chromatographic purification of angiotensin converting enzyme, Biochemistry, 23, 1037, 10.1021/bi00300a036

Patchett, 1985, The design and properties of N-carboxyalkyldipeptide inhibitors of angiotensin converting enzyme, Adv. Enzym., 57, 1

Schulleck, 1989, Angiotensin converting enzyme: substrate inhibition, Peptides, 10, 431, 10.1016/0196-9781(89)90054-5

Shai, 1990, Genomic DNA 5′ to the mouse and human angiotensin-converting enzyme genes contains two distinct regions of conserved sequence, Biochem. biophys. Res. Commun., 167, 1128, 10.1016/0006-291X(90)90640-9

Skidgel, 1985, Novel activity of human angiotensin I-converting enzyme: release of the NH2- and COOH-terminal tripeptides from the luteinizing hormone-releasing hormone, 82, 1025

Soubrier, 1988, Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning, 85, 9386

Strittmatter, 1986, Characterization of angiotensin converting enzyme by [3H]captopril binding, Molec. Pharmac., 29, 142

Strittmatter, 1987, Angiotensin converting enzyme immunohistochemistry in rat brain and pituitary gland: correlation of isozyme type with cellular localization, Neuroscience, 21, 407, 10.1016/0306-4522(87)90131-X

Strittmatter, 1985, A rat brain isozyme of angiotensinconverting enzyme. Unique specificity for amidated peptide substrates, J. biol. Chem., 260, 9825, 10.1016/S0021-9258(17)39310-9

Studdy, 1983, Angiotensinconverting enzyme and its clinical significance—a review, J. clin. Path., 36, 938, 10.1136/jcp.36.8.938

Unger, 1990, Converting enzyme inhibitors, 379

Vallee, 1990, Zinc coorclination, function, and structure of zinc enzymes and other proteins, Biochemistry, 29, 5647, 10.1021/bi00476a001

Vallotton, 1987, The renin-angiotensin system, Trends Pharmac. Sci., 8, 69, 10.1016/0165-6147(87)90013-7

Velletri, 1985, Testicular angiotensin I-converting enzyme, Life Sci., 36, 1597, 10.1016/0024-3205(85)90362-5

Williams, 1991, Characterization of neuronal and endothelial forms of angiotensin converting enzyme in pig brain, J. Neurochem., 10.1111/j.1471-4159.1991.tb02115.x