Anesthetics as tEratogens: Nitrous Oxide Is Fetotoxic, Xenon Is Not

American Association for the Advancement of Science (AAAS) - Tập 210 Số 4472 - Trang 899-901 - 1980
Geoffrey A. Lane1, Michael L. Nahrwold1, Alan R. Tait1, M. Taylor-Busch1, Peter J. Cohen1, Adrien R. Beaudoin2
1Department of Anesthesiology, University of Michigan Hospital, Ann Arbor 48109
2Department of Anatomy, University of Michigan Hospital, Ann Arbor 48109

Tóm tắt

Exposure of pregnant rats to the anesthetic nitrous oxide on the ninth day of gestation causes fetal resorption, skeletal anomalies, and macroscopic lesions including encephalocele, anophthalmia, microphthalmia, and gastroschisis. The inert gas xenon, which has anesthetic properties similar to those of nitrous oxide, does not cause teratogenic effects under the same experimental conditions.

Từ khóa


Tài liệu tham khảo

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Thông tin xuất bản

American Association for the Advancement of Science (AAAS)

Tập 210 Số 4472

899-901

Thông tin tác giả