Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications
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De Rosa, 2001, 11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity, Nat. Med., 7, 245, 10.1038/84701
De Rosa, 2001, Eleven-color flow cytometry. A powerful tool for elucidation of the complex immune system, Clin. Lab. Med., 21, 697
Marodi, 2001, Cytokine receptor signalling in neonatal macrophages: defective STAT-1 phosphorylation in response to stimulation with IFN-gamma, Clin. Exp. Immunol., 126, 456, 10.1046/j.1365-2249.2001.01693.x
Pala, 2000, Flow cytometric measurement of intracellular cytokines, J. Immunol. Methods, 243, 107, 10.1016/S0022-1759(00)00230-1
Schmitz, 1993, Regulation of T helper cell cytokine expression: functional dichotomy of antigen-presenting cells, Eur. J. Immunol., 23, 191, 10.1002/eji.1830230130
Jung, 1993, Detection of intracellular cytokines by flow cytometry, J. Immunol. Methods, 159, 197, 10.1016/0022-1759(93)90158-4
Openshaw, 1995, Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations, J. Exp. Med., 182, 1357, 10.1084/jem.182.5.1357
Schlessinger, 2000, Cell signaling by receptor tyrosine kinases, Cell, 103, 211, 10.1016/S0092-8674(00)00114-8
McCubrey, 2000, Serine/threonine phosphorylation in cytokine signal transduction, Leukemia, 14, 9, 10.1038/sj.leu.2401657
Adams, 2003, Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?, Biochemistry, 42, 601, 10.1021/bi020617o
Davis, 2000, Signal transduction by the JNK group of MAP kinases, Cell, 103, 239, 10.1016/S0092-8674(00)00116-1
O'Shea, 2002, Cytokine signaling in 2002: new surprises in the Jak/Stat pathway, Cell, 109, S121, 10.1016/S0092-8674(02)00701-8
Kisseleva, 2002, Signaling through the JAK/STAT pathway, recent advances and future challenges, Gene, 285, 1, 10.1016/S0378-1119(02)00398-0
Singer, 2002, Control of T cell function by positive and negative regulators, Science, 296, 1639, 10.1126/science.1071551
Fiering, 1990, Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor, Genes Dev., 4, 1823, 10.1101/gad.4.10.1823
Ferrell, 1998, The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes, Science, 280, 895, 10.1126/science.280.5365.895
Ferrell, 2002, Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability, Curr. Opin. Cell Biol., 14, 140, 10.1016/S0955-0674(02)00314-9
Drevs, 2003, Receptor tyrosine kinases: the main targets for new anticancer therapy, Curr. Drug Targets, 4, 113, 10.2174/1389450033346885
Lohrisch, 2001, HER2/neu as a predictive factor in breast cancer, Clin. Breast Cancer, 2, 129, 10.3816/CBC.2001.n.017
Chow, 2001, Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors, Cytometry, 46, 72, 10.1002/cyto.1067
Krutzik, 2003, Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events, Cytometry, 55A, 61, 10.1002/cyto.a.10072
Petit, 1993, Assessment of fluorochromes for cellular structure and function studies by flow cytometry, Biol. Cell, 78, 1, 10.1016/0248-4900(93)90109-R
Mullins, 1994, Overview of fluorophores, Methods Mol. Biol., 34, 107
Shapiro, 2001, Optical measurements in cytometry: light scattering, extinction, absorption, and fluorescence, Methods Cell Biol., 63, 107, 10.1016/S0091-679X(01)63009-7
Appay, 2002, The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining, J. Immunol. Methods, 268, 9, 10.1016/S0022-1759(02)00195-3
Whelan, 1999, Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent, J. Immunol., 163, 4342, 10.4049/jimmunol.163.8.4342
Skinner, 2000, Cutting edge: in situ tetramer staining of antigen-specific T cells in tissues, J. Immunol., 165, 613, 10.4049/jimmunol.165.2.613
Melan, 1999, Overview of cell fixatives and cell membrane permeants, Methods Mol. Biol., 115, 45
Zell, 2001, Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo, Proc. Natl. Acad. Sci. U.S.A., 98, 10805, 10.1073/pnas.191567898
Perez, 2002, Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry, Nat. Biotechnol., 20, 155, 10.1038/nbt0202-155
Tazzari, 2002, Flow cytometric detection of total and serine 473 phosphorylated Akt, J. Cell. Biochem., 86, 704, 10.1002/jcb.10262
Ormerod, 2002, Investigating the relationship between the cell cycle and apoptosis using flow cytometry, J. Immunol. Methods, 265, 73, 10.1016/S0022-1759(02)00071-6
Fleisher, 1999, Detection of intracellular phosphorylated STAT-1 by flow cytometry, Clin. Immunol., 90, 425, 10.1006/clim.1998.4654
Uzel, 2001, Detection of intracellular phosphorylated STAT-4 by flow cytometry, Clin. Immunol., 100, 270, 10.1006/clim.2001.5078
Juan, 1998, Phosphorylation of retinoblastoma protein assayed in individual HL-60 cells during their proliferation and differentiation, Exp. Cell Res., 244, 83, 10.1006/excr.1998.4165
Juan, 1998, Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis, Cytometry, 32, 71, 10.1002/(SICI)1097-0320(19980601)32:2<71::AID-CYTO1>3.0.CO;2-H
Marodi, 1994, Candidacidal mechanisms in the human neonate. Impaired IFN-gamma activation of macrophages in newborn infants, J. Immunol., 153, 5643, 10.4049/jimmunol.153.12.5643
Zell, 2002, Flow cytometric analysis of T cell receptor signal transduction, Sci. STKE, 2002, PL5, 10.1126/stke.2002.128.pl5
Altman, 1996, Phenotypic analysis of antigen-specific T lymphocytes, Science, 274, 94, 10.1126/science.274.5284.94
Constantin, 2002, Major histocompatibility complex (MHC) tetramer technology: an evaluation, Biol. Res. Nurs., 4, 115, 10.1177/1099800402238332
Blattman, 2000, Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection, J. Immunol., 165, 6081, 10.4049/jimmunol.165.11.6081
Klenerman, 2002, Tracking T cells with tetramers: new tales from new tools, Nat. Rev., Immunol., 2, 263, 10.1038/nri777
Dunbar, 2002, Oligomeric MHC molecules and their homologues: state of the art, J. Immunol. Methods, 268, 3, 10.1016/S0022-1759(02)00194-1
Gallimore, 1998, Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes, J. Exp. Med., 187, 1383, 10.1084/jem.187.9.1383
Flynn, 1998, Virus-specific CD8+ T cells in primary and secondary influenza pneumonia, Immunity, 8, 683, 10.1016/S1074-7613(00)80573-7
Belz, 2001, Virus-specific and bystander CD8+ T-cell proliferation in the acute and persistent phases of a gammaherpesvirus infection, J. Virol., 75, 4435, 10.1128/JVI.75.9.4435-4438.2001
Busch, 1998, Coordinate regulation of complex T cell populations responding to bacterial infection, Immunity, 8, 353, 10.1016/S1074-7613(00)80540-3
Masopust, 2001, Preferential localization of effector memory cells in nonlymphoid tissue, Science, 291, 2413, 10.1126/science.1058867
Lechner, 2001, Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers, Rev. Med. Virol., 11, 11, 10.1002/rmv.295
Kelleher, 2000, Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells, Curr. Opin. Immunol., 12, 370, 10.1016/S0952-7915(00)00102-3
Lechner, 2000, CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained, Eur. J. Immunol., 30, 2479, 10.1002/1521-4141(200009)30:9<2479::AID-IMMU2479>3.0.CO;2-B
Koehne, 2002, Quantitation, selection, and functional characterization of Epstein–Barr virus-specific and alloreactive T cells detected by intracellular interferon-gamma production and growth of cytotoxic precursors, Blood, 99, 1730, 10.1182/blood.V99.5.1730
Gillespie, 2000, Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors, J. Virol., 74, 8140, 10.1128/JVI.74.17.8140-8150.2000
Beske, 2002, High-throughput cell analysis using multiplexed array technologies, Drug Discovery Today, 7, S131, 10.1016/S1359-6446(02)02388-7
Moore, 2001, Cell-based versus isolated target screening: how lucky do you feel?, J. Biomol. Screening, 6, 69, 10.1177/108705710100600202
Buchdunger, 2000, Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors, J. Pharmacol. Exp. Ther., 295, 139
Buchdunger, 2002, Pharmacology of imatinib (STI571), Eur. J. Cancer, 38, S28, 10.1016/S0959-8049(02)80600-1
Druker, 2001, Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia, N. Engl. J. Med., 344, 1031, 10.1056/NEJM200104053441401
Fjallskog, 2003, Expression of molecular targets for tyrosine kinase receptor antagonists in malignant endocrine pancreatic tumors, Clin. Cancer Res., 9, 1469
Tashiro, 2003, Overexpression of cyclin D1 contributes to malignancy by up-regulation of fibroblast growth factor receptor 1 via the pRB/E2F pathway, Cancer Res., 63, 424
Kmet, 2003, A review of p53 expression and mutation in human benign, low malignant potential, and invasive epithelial ovarian tumors, Cancer, 97, 389, 10.1002/cncr.11064
Page, 2000, Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis, Anticancer Res., 20, 407
Huang, 2001, Signaling pathways in apoptosis as potential targets for cancer therapy, Trends Cell Biol., 11, 343, 10.1016/S0962-8924(01)02063-3
Landberg, 1990, Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: a new view of the cell cycle, Exp. Cell Res., 187, 111, 10.1016/0014-4827(90)90124-S
Zamai, 2002, Intracellular detection of Bcl-2 and p53 proteins by flow cytometry: comparison of monoclonal antibodies and sample preparation protocols, J. Biol. Regul. Homeostatic Agents, 16, 289
Lee, 2002, Multiparametric flow cytometric analysis in a breast cancer cell line (MCF-7), J. Obstet. Gynaecol. Res., 28, 141, 10.1046/j.1341-8076.2002.00005.x
Lecoeur, 2002, Multiparametric flow cytometric analysis of biochemical and functional events associated with apoptosis and oncosis using the 7-aminoactinomycin D assay, J. Immunol. Methods, 265, 81, 10.1016/S0022-1759(02)00072-8
Verdier, 2000, Optimization of cell permeabilization for multiparametric flow cytometric analysis with lectin staining, Cytometry, 41, 55, 10.1002/1097-0320(20000901)41:1<55::AID-CYTO8>3.0.CO;2-A
Lecoeur, 1998, A cytofluorometric method for the simultaneous detection of both intracellular and surface antigens of apoptotic peripheral lymphocytes, J. Immunol. Methods, 217, 11, 10.1016/S0022-1759(98)00060-X
Kohler, 2002, Evaluation of caspase activity in apoptotic cells, J. Immunol. Methods, 265, 97, 10.1016/S0022-1759(02)00073-X
Smolewski, 2002, Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis, J. Immunol. Methods, 265, 111, 10.1016/S0022-1759(02)00074-1
Bordignon, 2002, Flow cytometry assay for intracellular rabies virus detection, J. Virol. Methods, 105, 181, 10.1016/S0166-0934(02)00064-2
Mascola, 2002, Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells, J. Virol., 76, 4810, 10.1128/JVI.76.10.4810-4821.2002
Ruitenberg, 2003, A rapid flow cytometric method for the detection of intracellular cyclooxygenases in human whole blood monocytes and a COX-2 inducible human cell line, J. Immunol. Methods, 274, 93, 10.1016/S0022-1759(02)00507-0